Difference between revisions of "BrainRegionLAC FD HT MPO"

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<pre style="color: green">Median Preoptic Nucleus</pre>
 
<pre style="color: green">Median Preoptic Nucleus</pre>
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_MPO]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_MPO]]
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* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> [[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus]] (LAC.FD.HT.MPO) (see [[OverallMindMaps|Mind Maps]])
 
* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> [[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus]] (LAC.FD.HT.MPO) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': nucleus
 
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]]
+
* '''Quality''': L0
 +
* '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]] (LAC)
 +
* '''Area circuit''': Autonomic Thermoregulation (LAT)
 
* '''Role''': processor.autonomic
 
* '''Role''': processor.autonomic
 
* '''Function''': generates thirst
 
* '''Function''': generates thirst
* '''Notes to function''': Drinking decreases noradrenaline release in median preoptic nucleus
+
* '''Notes to function''':  
 +
** Drinking decreases noradrenaline release in median preoptic nucleus
 
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= Components =
 
= Components =
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_MPD|FAM.FT.AM.MPD]] || Medial Posterior Dorsal Amygdaloid Nucleus || inhibitory-gaba || [http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (AMY -> HYP, abstract)]
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_MPD|FAM.FT.AM.MPD]] || Medial Posterior Dorsal Amygdaloid Nucleus || inhibitory-gaba || uncertain ||[http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (AMY -> HYP, abstract)]
 
|-
 
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HC_CA1D|FMM.FT.HC.CA1D]] || Distal CA1 of Hippocampus || excitatory-glu || [http://www.nature.com/nrn/journal/v5/n7 Feeling (HC -> HT, abstract)]
+
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HC_CA1D|FMM.FT.HC.CA1D]] || Distal CA1 of Hippocampus || excitatory-glu || uncertain ||[http://www.nature.com/nrn/journal/v5/n7 Feeling (HC -> HT, abstract)]
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> MPO)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> MPO)]
 
|-
 
|-
|  || [[BrainRegionLAC_FD_HT_PRM|LAC.FD.HT.PRM]] || Premammillary Nucleus || excitatory-glu || (unknown reference)
+
|  || [[BrainRegionLAC_FD_HT_PRM|LAC.FD.HT.PRM]] || Premammillary Nucleus || excitatory-glu || uncertain ||(unknown reference)
 
|-
 
|-
|  || [[BrainRegionLAC_FD_HT_SCN|LAC.FD.HT.SCN]] || Suprachiasmatic Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)]
+
|  || [[BrainRegionLAC_FD_HT_SCN|LAC.FD.HT.SCN]] || Suprachiasmatic Nucleus || excitatory-glu || uncertain ||[http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)]
 
|-
 
|-
|  || [[BrainRegionLAC_HL_TGS_PE5|LAC.HL.TGS.PE5]] || Peritrigeminal Nucleus || excitatory-glu || (unknown reference)
+
|  || [[BrainRegionLAC_HL_TGS_PE5|LAC.HL.TGS.PE5]] || Peritrigeminal Nucleus || excitatory-glu || uncertain ||(unknown reference)
 
|-
 
|-
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_FD_TH_PV|NDM.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || excitatory-glu || (unknown reference)
+
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_FD_TH_PV|NDM.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference)
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
+
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_TH_PT|FAM.FD.TH.PT]] || Paratenial Nucleus of Thalamus || excitatory-glu || (unknown reference)
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_TH_PT|FAM.FD.TH.PT]] || Paratenial Nucleus of Thalamus || excitatory-glu || uncertain || (unknown reference)
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_AH|LAC.FD.HT.AH]] || Anterior Hypothalamic Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> AH)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_AH|LAC.FD.HT.AH]] || Anterior Hypothalamic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> AH)]
 
|-
 
|-
|  || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA)]
+
|  || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA)]
 
|-
 
|-
|  || [[BrainRegionLAC_FD_HT_SO|LAC.FD.HT.SO]] || Supraoptic Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> SON)]
+
|  || [[BrainRegionLAC_FD_HT_SO|LAC.FD.HT.SO]] || Supraoptic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> SON)]
 
|-
 
|-
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HL_RP_OB|LMC.HL.RP.OB]] || Raphe Obscurus Nucleus || excitatory-glu || (unknown reference)
+
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HL_RP_OB|LMC.HL.RP.OB]] || Raphe Obscurus Nucleus || excitatory-glu || uncertain || (unknown reference)
 
|}
 
|}
  
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(generated)
  
* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference]
+
* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference] (CL.INTRAHYPOTHALAMIC)
  
<img src="http://ahuman.org/svn/ahwiki/images/ext/812cda92ff47d048aeb22ce670a9a9fb.png" alt="unavailable" style="max-width: 100%;">
+
AH=[[BrainRegionLAC_FD_HT_AH|Anterior Hypothalamic Nucleus,LAC.FD.HT.AH]]
 +
ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 +
DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 +
LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 +
MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
 +
PA=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
SCH=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 +
SON=[[BrainRegionLAC_FD_HT_SO|Supraoptic Nucleus,LAC.FD.HT.SO]]
 +
VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/812cda92ff47d048aeb22ce670a9a9fb.png" alt=alt="unavailable" style="max-width: 100%;">
  
* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference]
+
* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES)
  
<img src="http://ahuman.org/svn/ahwiki/images/ext/aaf05c2cb0453d5f112754ade7c03956.jpg" alt="unavailable" style="max-width: 100%;">
+
ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 +
DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 +
LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 +
MPO=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
 +
PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 +
VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]]
 +
VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/aaf05c2cb0453d5f112754ade7c03956.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference]
+
* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference] (CM.ONUF)
  
<img src="http://ahuman.org/svn/ahwiki/images/ext/b3238c9c6efdcfa004931bec8815fc0b.jpeg" alt="unavailable" style="max-width: 100%;">
+
CN=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
DVM=[[BrainRegionLAC_HL_VGN|Vagus Nucleus,LAC.HL.VGN]]
 +
IMG=[[BrainRegionLAC_PN_SYM_IMG|Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG]]
 +
IML=[[BrainRegionLAC_SC_IZ_IML|Intermediolateral Nucleus,LAC.SC.IZ.IML]]
 +
LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 +
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 +
MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
 +
NBM=[[BrainRegionLMC_FT_NBM|Basal Nucleus of Meynert,LMC.FT.NBM]]
 +
ONF=[[BrainRegionLPC_SC_VH_ONF|Onuf's Nucleus,LPC.SC.VH.ONF]]
 +
PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]]
 +
PEL=[[BrainRegionLAC_PN_PSYM_PPG|Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG]]
 +
PU=[[BrainRegionFEC_FT_PU_LT|Dorsal Putamen Lateral,FEC.FT.PU.LT]]
 +
PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
SNC=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]]
 +
SPS=[[BrainRegionLAC_SC_IZ_SPS|Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS]]
 +
VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 +
ZI=[[BrainRegionFEC_FD_STN_CD|Subthalamic Nucleus Caudal,BGA.FD.STN.ZI]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/b3238c9c6efdcfa004931bec8815fc0b.jpeg" alt=alt="unavailable" style="max-width: 100%;">
  
  

Latest revision as of 18:27, 28 April 2019

Median Preoptic Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLAC -> BrainRegionLAC_FD_HT_MPO


This page covers biological details of component Median Preoptic Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> Median Preoptic Nucleus (LAC.FD.HT.MPO) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Autonomous Control Area (LAC)
  • Area circuit: Autonomic Thermoregulation (LAT)
  • Role: processor.autonomic
  • Function: generates thirst
  • Notes to function:
    • Drinking decreases noradrenaline release in median preoptic nucleus

(generated)

Components

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  • no child items defined

Connectivity

(generated)


LAC.FD.HT.MPO.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FT.AM.MPD Medial Posterior Dorsal Amygdaloid Nucleus inhibitory-gaba uncertain Role for serotonin in moral behavior (AMY -> HYP, abstract)
FMM FMM.FT.HC.CA1D Distal CA1 of Hippocampus excitatory-glu uncertain Feeling (HC -> HT, abstract)
LAC LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus excitatory-glu uncertain Eating and sleeping to survive (DMH -> MPO)
LAC.FD.HT.PRM Premammillary Nucleus excitatory-glu uncertain (unknown reference)
LAC.FD.HT.SCN Suprachiasmatic Nucleus excitatory-glu uncertain Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)
LAC.HL.TGS.PE5 Peritrigeminal Nucleus excitatory-glu uncertain (unknown reference)
NDM NDM.FD.TH.PV Paraventricular Nucleus of Thalamus excitatory-glu uncertain (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FAM FAM.FD.TH.PT Paratenial Nucleus of Thalamus excitatory-glu uncertain (unknown reference)
LAC LAC.FD.HT.AH Anterior Hypothalamic Nucleus excitatory-glu uncertain Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> AH)
LAC.FD.HT.PV Paraventricular Nucleus excitatory-glu uncertain Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA)
LAC.FD.HT.SO Supraoptic Nucleus excitatory-glu uncertain Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> SON)
LMC LMC.HL.RP.OB Raphe Obscurus Nucleus excitatory-glu uncertain (unknown reference)

Thirdparty Circuits

(generated)

AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
PA=Paraventricular Nucleus,LAC.FD.HT.PV
SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
SON=Supraoptic Nucleus,LAC.FD.HT.SO
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
DVM=Vagus Nucleus,LAC.HL.VGN
IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG
IML=Intermediolateral Nucleus,LAC.SC.IZ.IML
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
NBM=Basal Nucleus of Meynert,LMC.FT.NBM
ONF=Onuf's Nucleus,LPC.SC.VH.ONF
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG
PU=Dorsal Putamen Lateral,FEC.FT.PU.LT
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS
VTA=Ventral Tegmental Area,LMC.MM.VTA
ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI


References

(generated)