Difference between revisions of "BrainRegionNMA NC SMC F6"

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<pre style="color: green">Pre-Supplementary Motor Area</pre>
 
<pre style="color: green">Pre-Supplementary Motor Area</pre>
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaNMA]] -> [[BrainRegionNMA_NC_SMC_F6]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaNMA]] -> [[BrainRegionNMA_NC_SMC_F6]]
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Region is part of aHuman target integrated biological model.
 
Region is part of aHuman target integrated biological model.
  
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* '''Top-down path to region''': Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> [[BrainCenterNMA_NC_SMC|Supplementary Motor Cortex]] (NMA.NC.SMC) (NMA.NC.SMC) -> [[BrainRegionNMA_NC_SMC_F6|Pre-Supplementary Motor Area]] (NMA.NC.SMC.F6) (NMA.NC.SMC.F6) (see [[OverallMindMaps|Mind Maps]])
+
* '''Top-down path to region''': Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> [[BrainCenterNMA_NC_SMC|Supplementary Motor Cortex]] (NMA.NC.SMC) -> [[BrainRegionNMA_NC_SMC_F6|Pre-Supplementary Motor Area]] (NMA.NC.SMC.F6) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': cortex
 
* '''Type''': cortex
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* '''Brain area''': [[BrainAreaNMA|Neocortical Brain - Motor Aggregation Area]]
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* '''Quality''': L0
 +
* '''Brain area''': [[BrainAreaNMA|Neocortical Brain - Motor Aggregation Area]] (NMA)
 +
* '''Area circuit''': Complex Motor (SEQ)
 
* '''Brodmann ID''': 06
 
* '''Brodmann ID''': 06
−
* '''Role''': processor
+
* '''Role''': cortex.generic
 
* '''Function''': High level motor functions; Numerical and verbal mental-operation tasks
 
* '''Function''': High level motor functions; Numerical and verbal mental-operation tasks
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* '''Notes to function''': from TH/VLpc, MD from caudate, CR; F5/24c/46; no connections with F1
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* '''Notes to function''':  
 +
** from TH/VLpc, MD from caudate, CR
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**  F5/24c/46
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**  no connections with F1
 
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= Components =
 
= Components =
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
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| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
−
| [[BrainAreaNMA|NMA]] || [[BrainRegionNMA_FD_TH_VL|NMA.FD.TH.VL]] || Ventral Lateral Nucleus || excitatory-glu || [http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html Basal Ganglia Activity (VLo -> SMC, abstract)]
+
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_DLPFCR|NDM.NC.AL.DLPFCR]] || Rostral Mid-Dorsolateral Prefrontal Cortex || feedforward-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (46 -> F6, abstract)]
 +
|-
 +
| [[BrainAreaNMA|NMA]] || [[BrainRegionNMA_FD_TH_VA|NMA.FD.TH.VA]] || Ventral Anterior Nucleus || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (BTH -> F6)]
 +
|-
 +
|  || [[BrainRegionNMA_FD_TH_VL|NMA.FD.TH.VL]] || Ventral Lateral Nucleus || excitatory-glu || uncertain ||[http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html Basal Ganglia Activity (VLo -> SMC, abstract)]
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
−
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
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| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
−
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FD_STN_MED|FEC.FD.STN.MED]] || Subthalamic Nucleus Medial || excitatory-glu || (unknown reference)
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| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FD_STN_MED|FEC.FD.STN.MED]] || Subthalamic Nucleus Medial || excitatory-glu || uncertain || [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Serotonin regulation of subthalamic neurons (CTX -> STN, abstract)]
 
|-
 
|-
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| [[BrainAreaNMA|NMA]] || [[BrainRegionNMA_NC_PMC_F5|NMA.NC.PMC.F5]] || Ventral Rostral Premotor Cortex || feedforward-glu || [http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (F6 -> F5)]
+
|  || [[BrainRegionFEC_FT_PU_MED|FEC.FT.PU.MED]] || Dorsal Putamen Medial || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (F6 -> BG, abstract)]
 +
|-
 +
| [[BrainAreaNMA|NMA]] || [[BrainRegionNMA_NC_PMC_F4|NMA.NC.PMC.F4]] || Ventral Caudal Premotor Cortex || feedforward-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (F6 -> F4)]
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|-
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|  || [[BrainRegionNMA_NC_PMC_F5|NMA.NC.PMC.F5]] || Ventral Rostral Premotor Cortex || feedforward-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0893608098000471 Primate Control of Grasping (F6 -> F5)]
 
|}
 
|}
  
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* [http://ars.els-cdn.com/content/image/1-s2.0-S0893608098000471-gr6.gif Primate Control of Grasping] - see [http://www.sciencedirect.com/science/article/pii/S0893608098000471 Reference]
+
* [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/graphic/revneuro-2014-0004_fig1.jpg Serotonin regulation of subthalamic neurons] - see [http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml Reference] (CM.SUBTHALAMUS)
 +
 
 +
CTX=Anterior Lobe,NC.LOBE.ANT
 +
GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
PPN=[[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]]
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SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]])
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/7c0828e642ed771ff576b3f3a6362c50.jpg" alt=alt="unavailable" style="max-width: 100%;">
 +
 
 +
* [http://ars.els-cdn.com/content/image/1-s2.0-S0893608098000471-gr6.gif Primate Control of Grasping] - see [http://www.sciencedirect.com/science/article/pii/S0893608098000471 Reference] (CM.GRASPING-CONTROL)
  
−
<img src="http://ars.els-cdn.com/content/image/1-s2.0-S0893608098000471-gr6.gif" alt="unavailable">
+
46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]])
 +
AIP=[[BrainRegionNSA_NC_IPS_AIP|Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP]]
 +
BG=[[BrainCenterFEC_FT_BG|Basal Ganglia,FEC.FT.BG]]
 +
BTH=[[BrainRegionNMA_FD_TH_VA|Ventral Anterior Nucleus,NMA.FD.TH.VA]]
 +
F1=[[BrainRegionNMA_NC_MC|Motor Cortex,NMA.NC.MC]]
 +
F2=[[BrainRegionNMA_NC_PMC_F2|Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2]]
 +
F4=[[BrainRegionNMA_NC_PMC_F4|Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4]]
 +
F5=[[BrainRegionNMA_NC_PMC_F5|Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5]]
 +
F6=[[BrainRegionNMA_NC_SMC_F6|Pre-Supplementary Motor Area,NMA.NC.SMC.F6]]
 +
IT=[[BrainCenterNSA_NC_IT|Inferotemporal Area,NSA.NC.IT]]
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PIP=Posterior Eye Field,NPE.NC.IPS.PEF (see [[BrainCenterNSA_NC_IPS|Intraparietal Sulcus]])
 +
S1=[[BrainRegionNCP_NC_PG_S1|Primary Somatosensory Cortex,NCP.NC.PG.S1]]
 +
S2=[[BrainRegionNCP_NC_PG_S1|Primary Somatosensory Cortex,NCP.NC.PG.S1]]
 +
VC=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]]
 +
VIP=[[BrainRegionNSA_NC_IPS_VIP|Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/a2a7d1647f97dffbf0bc8e8d275ab006.gif" alt=alt="unavailable" style="max-width: 100%;">
  
  
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* http://www.degruyter.com/view/j/revneuro.2014.25.issue-4/revneuro-2014-0004/revneuro-2014-0004.xml
 
* http://www.sciencedirect.com/science/article/pii/S0893608098000471
 
* http://www.sciencedirect.com/science/article/pii/S0893608098000471

Latest revision as of 18:33, 28 April 2019

Pre-Supplementary Motor Area

@@Home -> BiologicalLifeResearch -> BrainAreaNMA -> BrainRegionNMA_NC_SMC_F6

This page covers biological details of component Pre-Supplementary Motor Area. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Supplementary Motor Cortex (NMA.NC.SMC) -> Pre-Supplementary Motor Area (NMA.NC.SMC.F6) (see Mind Maps)
  • Type: cortex
  • Quality: L0
  • Brain area: Neocortical Brain - Motor Aggregation Area (NMA)
  • Area circuit: Complex Motor (SEQ)
  • Brodmann ID: 06
  • Role: cortex.generic
  • Function: High level motor functions; Numerical and verbal mental-operation tasks
  • Notes to function:
    • from TH/VLpc, MD from caudate, CR
    • F5/24c/46
    • no connections with F1

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Components

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  • no child items defined

Connectivity

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NMA.NC.SMC.F6.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
NDM NDM.NC.AL.DLPFCR Rostral Mid-Dorsolateral Prefrontal Cortex feedforward-glu uncertain Primate Control of Grasping (46 -> F6, abstract)
NMA NMA.FD.TH.VA Ventral Anterior Nucleus excitatory-glu uncertain Primate Control of Grasping (BTH -> F6)
NMA.FD.TH.VL Ventral Lateral Nucleus excitatory-glu uncertain Basal Ganglia Activity (VLo -> SMC, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FEC FEC.FD.STN.MED Subthalamic Nucleus Medial excitatory-glu uncertain Serotonin regulation of subthalamic neurons (CTX -> STN, abstract)
FEC.FT.PU.MED Dorsal Putamen Medial excitatory-glu uncertain Primate Control of Grasping (F6 -> BG, abstract)
NMA NMA.NC.PMC.F4 Ventral Caudal Premotor Cortex feedforward-glu uncertain Primate Control of Grasping (F6 -> F4)
NMA.NC.PMC.F5 Ventral Rostral Premotor Cortex feedforward-glu uncertain Primate Control of Grasping (F6 -> F5)

Thirdparty Circuits

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CTX=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia)
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)


46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
AIP=Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP
BG=Basal Ganglia,FEC.FT.BG
BTH=Ventral Anterior Nucleus,NMA.FD.TH.VA
F1=Motor Cortex,NMA.NC.MC
F2=Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2
F4=Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4
F5=Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5
F6=Pre-Supplementary Motor Area,NMA.NC.SMC.F6
IT=Inferotemporal Area,NSA.NC.IT
PIP=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus)
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Primary Somatosensory Cortex,NCP.NC.PG.S1
VC=Occipital Lobe,NC.LOBE.OCC
VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP


References

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