BrainRegionNPE NC SMC SEF
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Supplementary Eye Field
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This page covers biological details of component Supplementary Eye Field. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Supplementary Motor Cortex (NMA.NC.SMC) -> Supplementary Eye Field (NPE.NC.SMC.SEF) (see Mind Maps)
- Type: cortex
- Brain area: Neocortical Brain - Unimodal Execution Area
- Brodmann ID: 06
- Role: cortex.generic
- Function: high level aspects of saccade control
- Notes to function: Complex spatial transformations, learned transformations, and executive cognitive functions; dorsorostral of F7
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| NDM | NDM.NC.AL.DLPFCR | Rostral Mid-Dorsolateral Prefrontal Cortex | feedforward-glu | 3 Visual Cortex Paths (LPC -> pre-SMA, abstract) |
| NPE | NPE.NC.SPL.PG | Caudal Precuneus | feedforward-glu | Movement Planning (PPC -> SMC, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| LRC | LRC.MM.RP.RIP | Raphe Interpositus Nucleus | excitatory-glu | Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract) |
| NPE | NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | feedforward-glu | Summary of eye movement control (SEF -> FEF, abstract) |
Thirdparty Circuits
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- Horizontal saccades and smooth pursuit movements - see Reference (CP.VISION-SACCADES)
Bechterew=Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FEFSEF=Anterior Lobe,NC.LOBE.ANT LGB=Lateral Geniculate Nucleus,NSA.FD.LGN PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) PrimaryVisual=Primary Visual Cortex,NSA.NC.OCC.V1 RIP=Raphe Interpositus Nucleus,LRC.MM.RP.RIP SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) Vestibular=Superior Vestibular Nucleus,LPC.HT.SVBN VisualAssociation=Caudal Precuneus,NPE.NC.SPL.PG
- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Summary of eye movement control - see Reference (CP.EYE-FIELDS)
DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) PEF=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF riMLF=Cajal Nucleus,LRC.MM.CJ
- Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)
AMYG=Amygdala,FAM.FT.AM CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL Thalamus=Thalamus,FD.TH VTA=Ventral Tegmental Area,LMC.MM.VTA
References
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