BrainCenterNC ACG

Anterior Cingulate Area

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This page covers biological details of component group Anterior Cingulate Area. Component group is part of aHuman target integrated biological model.

• Top-down path to center: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Anterior Cingulate Area (NC.ACG) (see Mind Maps)
• Function:
• Notes to function: consists of anterior cingulate cortex and middle cingulate cortex

(generated)

Components

(generated)

Component items:

• Anterior Cingulate Cortex (NC.AL.ACG): Error Correction
  • Ventral Anterior Cingulate Area (NDM.NC.AL.VACG): Seat of Free Will
  • Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG): Rational Thought Processes
  • Subgenual Cingulate Cortex (NCP.NC.AL.SGCG): Influences changes in appetite and sleep
• Medial Cingulate Cortex (NC.AL.MCG): Error Correction
  • Ventral Medial Cingulate Area (NDM.NC.AL.VMCG): Response Selection
  • Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG): Rational Thought Processes
  • Pregenual Cingulate Cortex (NDM.NC.AL.PGCG): Sensation of Emotion

Connectivity

(generated)

Internal Regions Connections:

Source Region	Target Region	Reference
Subgenual Cingulate Cortex (NCP.NC.AL.SGCG)	Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG)	Regulation of Social Brain (SGC -> DACC)
	Ventral Anterior Cingulate Area (NDM.NC.AL.VACG)	Regulation of Social Brain (SGC -> VACC)
Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG)	Ventral Anterior Cingulate Area (NDM.NC.AL.VACG)	Principal Connections of Hippocampus (DorsalCingulate -> VentralCingulate)

External Connections:

External Inbound Center Connections:

Source Center	Sample Link	Reference
Amygdala (FAM.FT.AM)	FAM.FT.AM.AB -> NDM.NC.AL.DACG	Amygdalar disruption of prefrontal cortex (AM -> ACG, abstract)
Cognitive Thalamus (FD.TH.CR)	NMA.FD.TH.MDL -> NDM.NC.AL.DACG	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
Motor Thalamus (FD.TH.MR)	FMM.FD.TH.LD -> NDM.NC.AL.DACG	Thalamocortical relationships (LD -> pLD, abstract)
Sensory Thalamus (FD.TH.SR)	NCP.FD.TH.LI -> NDM.NC.AL.DACG	Afferent pain pathways (Thalamus -> ACC, abstract)
Ventral Tegmental Area (LMC.MM.VTA)	LMC.MM.VTA -> NDM.NC.AL.DACG	(unknown reference)
Lateral Prefrontal Cortex (NC.AL.LPFC)	NDM.NC.AL.IPG -> NCP.NC.AL.SGCG	Regulation of Social Brain (IFG -> SGC)
Orbitomedial Prefrontal Cortex (NC.AL.OMPFC)	NDM.NC.AL.ROFCR -> NDM.NC.AL.DACG	Role for serotonin in moral behavior (OMPFC -> ACG, abstract)
Insular Cortex (NC.INS)	NCP.NC.INS.PPC -> NDM.NC.AL.DACG	Amygdalar disruption of prefrontal cortex (INS -> ACG, abstract)
Inferior Parietal Lobule (NC.IPL)	NPE.NC.IPL.MST -> NDM.NC.AL.DACG	Global visual system (ParietalCortex -> FrontalCortex, abstract)
Superior Parietal Lobule (NC.SPL)	NPE.NC.SPL.PF -> NDM.NC.AL.DACG	Global visual system (ParietalCortex -> FrontalCortex, abstract)
Transverse Temporal Gyrus (NSA.NC.TTG)	NSA.NC.TTG.A2 -> NDM.NC.AL.DACG	Directed Effort Network (ACA -> dACC)

External Outbound Center Connections:

Target Center	Sample Link	Reference
Amygdala (FAM.FT.AM)	NDM.NC.AL.DACG -> FAM.FT.AM.BP	Role for serotonin in moral behavior (ACG -> AMY, abstract)
Central Extended Amygdala (FAM.FT.CEAM)	NCP.NC.AL.SGCG -> FAM.FT.BNST	(unknown reference)
Hypothalamus (FD.HT)	NCP.NC.AL.SGCG -> LAC.FD.HT.AH	(unknown reference)
Subthalamus Area (FEC.FD.STA)	NDM.NC.AL.DACG -> FEC.FD.STN.CD	Functional subdivisions of the subthalamic nucleus (ACG -> STN, abstract)
Basal Ganglia (FEC.FT.BG)	NDM.NC.AL.DACG -> FEC.FT.CN.HD	Global visual system (FrontalCortex -> BGA, abstract)
Pontine Reticular Formation (HT.RF)	NCP.NC.AL.SGCG -> LPC.HT.PRF.PB	Motor neurons control (CTX -> PRF, abstract)
Red Nucleus (LLC.MM.RD)	NDM.NC.AL.VACG -> LLC.MM.RD	Cerebellum functional divisions (CTX -> RD, abstract)
Locus Coeruleus (LMC.HT.LC)	NDM.NC.AL.VACG -> LMC.HT.LC	(unknown reference)
Periaqueductal Gray Matter (LMC.MM.PAG)	NCP.NC.AL.SGCG -> LMC.MM.PAG	(unknown reference)
Lateral Prefrontal Cortex (NC.AL.LPFC)	NDM.NC.AL.VACG -> NDM.NC.AL.DLPFCR	Role for serotonin in moral behavior (ACG -> LPFC, abstract)
Medial Parietal Lobule (NC.MPL)	NDM.NC.AL.DACG -> NCP.NC.MPL.PSCG	Global visual system (FrontalCortex -> ParietalCortex, abstract)
Premotor Cortex (NC.PMC)	NDM.NC.AL.DACG -> NMA.NC.PMC.F7	(unknown reference)