BrainRegionLRC MM CJ
Cajal Nucleus
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This page covers biological details of component Cajal Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Midbrain Mesencephalon -> Reflexes Nuclei of Midbrain Mesencephalon (MM.REF) -> Visual Reflexes Nuclei of Midbrain Mesencephalon (MM.REF.VIS) -> Supraoculomotor Area (VBA.MM.SOA) -> Cajal Nucleus (LRC.MM.CJ) (see Mind Maps)
- Type: nucleus
- Brain area: Lower Brain - Motor Reflex Area
- Role: subcortical.motor.flexor
- Function: Integration of head and eye movements, controls downward vertical gaze
- Notes to function: Projects to CN3, CN4 nuclei, rotation of body about its long axis, Project to vestibular nuclei
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| LPC | LPC.HL.VCOCH | Ventral Cochlear Nucleus | excitatory-glu | (unknown reference) |
| LRC | LRC.MM.SC.DEEP | Deep Superior Colliculus | excitatory-glu | Summary of eye movement control (SC -> riMLF, abstract) |
| NPE | NPE.NC.IPS.LIP | Lateral Intraparietal Sulcus | excitatory-glu | Vision Components (VAC -> SOA, abstract) |
| NPE.NC.OCC.V3D | Dorsal Associative Visual Cortex | excitatory-glu | Eye blink reflex and pupillary light reflex (VAC -> SupraOculomotor, abstract) | |
| NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | excitatory-glu | Summary of eye movement control (FEF -> riMLF, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| LPC | LPC.MM.OCN | Oculomotor Nucleus | excitatory-glu | Eye blink reflex and pupillary light reflex (SupraOculomotor -> Oculomotor, abstract) |
| LPC.MM.TRH | Trochlear Nucleus | excitatory-glu | (unknown reference) |
Thirdparty Circuits
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map: Abducens=Abducens Nucleus,LPC.HT.ABD, Ciliary=Ciliary Ganglion,LAC.PN.PSYM.CLG, EWN=Edinger-Westphal Nucleus,LAC.MM.EWN, EYE=Eye,TARGET.TSA.EYE, Facial=Facial Motor Nucleus,LPC.HT.FCM, Oculomotor=Oculomotor Nucleus,LPC.MM.OCN, Pretectum=Pretectum,MM.PT (Anterior Pretectum Nucleus (LRC.MM.PT.PTA), Nucleus of Optic Tract (LRC.MM.PT.NOT), Pretectal Olivary Nucleus (LRC.MM.PT.PON), Principal Pretectal Nucleus (LRC.MM.PT.PR), Sublentiform Nucleus (LRC.MM.PT.SL)), PrincipalTrigeminal=Principal Trigeminal Nucleus,LPC.HT.PN.PTR, RF=Pontine Reticular Formation,HT.RF, SpinalTrigeminal=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR, SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (Cajal Nucleus (LRC.MM.CJ), Rostral Interstitial Nucleus of MLF (LRC.MM.RIMLF), Darkschewitsch Nucleus (LRC.MM.DSCH)), VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (Dorsal Associative Visual Cortex (NPE.NC.OCC.V3D), Ventral Associative Visual Cortex (NPE.NC.OCC.V3V))
- Saccades and smooth movements (unknown reference)
map: CN=Caudate Nucleus,FEC.FT.CN (Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL)), CR=Cerebellum,LLC.HT.CR (Cerebellar Flocconodular Lobe (LRC.HT.CR.FN), Cerebellar Lateral Lobe (LLC.HT.CR.CC), Cerebellar Paravermis (LLC.HT.CR.PV), Cerebellar Vermis (LRC.HT.CR.VM)), DLPN=Oral Pontine Reticular Nucleus,LRC.HT.PRF.RPO, Extrastriate=Associative Visual Cortex,NPE.NC.OCC.V3 (Dorsal Associative Visual Cortex (NPE.NC.OCC.V3D), Ventral Associative Visual Cortex (NPE.NC.OCC.V3V)), FEF=Frontal Eye Field,NMA.NC.PMC.FEF (Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF)), PPC=Posterior Eye Field,NPE.NC.IPS.PEF (Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP)), PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (Oral Pontine Reticular Nucleus (LRC.HT.PRF.RPO), Caudal Pontine Reticular Nucleus (LRC.HT.PRF.CRF), Parvocellular Reticular Nucleus (LRC.HT.PRF.PVR)), SC=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SN=Substantia Nigra,FEC.FT.SN (Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT), Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED), Substantia Nigra Pars Reticulata Dorsolateral (FEC.FT.SNR.DL), Substantia Nigra Pars Reticulata Rostromedial (FEC.FT.SNR.RM), Substantia Nigra Pars Reticulata Ventrolateral (FEC.FT.SNR.VL), Substantia Nigra Pars Reticulata Medial (FEC.FT.SNR.MED)), Striate=Primary Visual Cortex,NSA.NC.OCC.V1, TEF=Inferotemporal Area,NSA.NC.IT, VGC=Cajal Nucleus,LRC.MM.CJ, Vestibular=Lateral Vestibular Nucleus,LPC.HT.LVBN
map: DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), FEF=Frontal Eye Field,NMA.NC.PMC.FEF (Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF)), PEF=Posterior Eye Field,NPE.NC.IPS.PEF (Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP)), PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (Oral Pontine Reticular Nucleus (LRC.HT.PRF.RPO), Caudal Pontine Reticular Nucleus (LRC.HT.PRF.CRF), Parvocellular Reticular Nucleus (LRC.HT.PRF.PVR)), SC=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SEF=Supplementary Eye Field,NPE.NC.SMC.SEF, riMLF=Cajal Nucleus,LRC.MM.CJ
References
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