BrainRegionNCP NC INS AIC
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Anterior Insular Cortex
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This page covers biological details of component Anterior Insular Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Insular Cortex (NC.INS) -> Anterior Insular Cortex (NCP.NC.INS.AIC) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Neocortical Brain - Conscious Personality Area
- Brodmann ID: 14
- Role: cortex.generic
- Function: Risky and moral decision making, articulation
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FT.EPF | Endopiriform Nucleus | excitatory-glu | Gustatory sensory system of rat and macaque (EnP -> Iav, abstract) |
| NCP | NCP.FD.TH.MDC | Central Mediodorsal Nucleus of Thalamus | excitatory-glu | Amygdalar disruption of prefrontal cortex (TH -> INS, abstract) |
| NCP.NC.INS.PIC | Posterior Insular Cortex | feedforward-glu | Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract) | |
| NCP.NC.TPC | Temporopolar Cortex | feedforward-glu | Directed Effort Network (tPole -> Insula, abstract) | |
| NSA | NSA.NC.PH.PIR | Piriform Cortex | feedforward-glu | Gustatory sensory system of rat and macaque (PiR -> Iav, abstract) |
| NSA.NC.PH.PRP | Prepyriform Cortex | feedforward-glu | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FMM | FMM.NC.PH.PER | Perirhinal Cortex | feedforward-glu | Gustatory sensory system of rat and macaque (Iav -> PrC, abstract) |
| NDM | NDM.NC.AL.IPG | Inferior Prefrontal Gyrus | feedforward-glu | Directed Effort Network (Insula -> fPole, abstract) |
| NDM.NC.AL.VACG | Ventral Anterior Cingulate Area | feedforward-glu | Amygdalar disruption of prefrontal cortex (INS -> ACG, abstract) |
Thirdparty Circuits
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- Directed Effort Network - see Reference (CT.DIRECTED-EFFORT-NETWORK)
AC22=Wernicke's area A4,NSA.NC.STG.A4 ACA=Auditory Association Area,NSA.NC.TTG.A2 AM=Amygdala,FAM.FT.AM DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) Insula=Insular Cortex,NC.INS OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PPC=Inferior Parietal Lobule,NC.IPL dACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG fPole=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG tPole=Temporopolar Cortex,NCP.NC.TPC vACC=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG
- Gustatory sensory system of rat and macaque - see Reference (CP.GUSTATORY-OLFACTORY)
EnP=Endopiriform Nucleus,FAM.FT.EPF Gud=Insular Cortex,NC.INS Gug=Insular Cortex,NC.INS HF=Hippocampal Formation,FMM.FT.HF IadIap=Insular Cortex,NC.INS Iav=Insular Cortex,NC.INS NST=Solitary Nucleus,LPC.HL.SOL PB=Parabrachial Nucleus,LPC.HT.PRF.PB PiR=Piriform Cortex,NSA.NC.PH.PIR PrC=Perirhinal Cortex,FMM.NC.PH.PER VPMpc=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
- Amygdalar disruption of prefrontal cortex - see Reference (CF.AM-DISRUPTION)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AM=Amygdala,FAM.FT.AM HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV INS=Insular Cortex,NC.INS LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PAG=Periaqueductal Gray Matter,LMC.MM.PAG PB=Parabrachial Nucleus,LPC.HT.PRF.PB PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE SOL=Solitary Nucleus,LPC.HL.SOL TH=Thalamus,FD.TH
References
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