BrainRegionLMC MM RP SUC

Superior Central Raphe Nucleus

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This page covers biological details of component Superior Central Raphe Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) -> Mesencephalic Reticular Formation, Midline Column (MM.RF.MID) -> Superior Central Raphe Nucleus (LMC.MM.RP.SUC) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Lower Brain - Modulatory Contol Area (LMC)
• Area circuit: Serotonin - Feelings of Well-Being and Happiness (5HT)
• Role: processor.autonomic
• Function: Block or temporarily suspend mnemonic processes in the hippocampus; Hallucinations
• Notes to function:
  • Directs HC to disregard insignificant events
  • inhibitory nucleus
  • B6,B8
  • Insomnia
  • inhibitory nucleus

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
FAM	FAM.FD.LHB.MED	Lateral Habenula Medial Part	excitatory-glu	uncertain	Habenula Connections (LHb -> MR, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
FAM	FAM.FT.SEP.LT	Lateral Septal Nucleus	modulatory-5ht	uncertain	(unknown reference)
FEC	FEC.FD.STN.ICD	Subthalamic Nucleus Internal Caudal	modulatory-5ht	uncertain	(unknown reference)
FMM	FMM.FD.MB.MMB	Medial Mammillary Nucleus	modulatory-5ht	uncertain	(unknown reference)
LAC	LAC.FD.HT.PN	Posterior Hypothalamic Nucleus	modulatory-5ht	uncertain	(unknown reference)
	LAC.FD.HT.SUM	Supramammillary Nucleus	modulatory-5ht	uncertain	(unknown reference)

Thirdparty Circuits

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• Habenula Connections - see Reference (CF.HB-CONNECTIONS)

CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
IP=Interpeduncular Nucleus,FEC.HT.TG.IPD
LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
LHb=Lateral Habenula,FAM.FD.LHB (see Habenula)
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
MHb=Medial Habenula,FAM.FD.MHB
MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC
PB=Endocrine Glands,TARGET.TEA.ENDOCRINE
S=Septal Nuclei,FAM.FT.SEP
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
VTA=Ventral Tegmental Area,LMC.MM.VTA

References

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• http://www.scholarpedia.org/article/Habenula