Difference between revisions of "BrainRegionFAM FD MHB"
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* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFAM_FD_HB|Habenula]] (FAM.FD.HB) -> [[BrainRegionFAM_FD_MHB|Medial Habenula]] (FAM.FD.MHB) (see [[OverallMindMaps|Mind Maps]]) | * '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFAM_FD_HB|Habenula]] (FAM.FD.HB) -> [[BrainRegionFAM_FD_MHB|Medial Habenula]] (FAM.FD.MHB) (see [[OverallMindMaps|Mind Maps]]) | ||
* '''Type''': nucleus | * '''Type''': nucleus | ||
| − | * '''Brain area''': [[BrainAreaFAM|Forebrain - Affective Motivations Area]] | + | * '''Quality''': L0 |
| + | * '''Brain area''': [[BrainAreaFAM|Forebrain - Affective Motivations Area]] (FAM) | ||
| + | * '''Area circuit''': Reward Emotions Control (FAMXREC) | ||
* '''Role''': processor.affective | * '''Role''': processor.affective | ||
* '''Function''': Encoding negative feedback, indirect | * '''Function''': Encoding negative feedback, indirect | ||
| − | * '''Notes to function''': affects VTA, dorsal raphe but via interpeduncular nucleus | + | * '''Notes to function''': |
| + | ** affects VTA, dorsal raphe but via interpeduncular nucleus | ||
(generated) | (generated) | ||
= Components = | = Components = | ||
| Line 28: | Line 31: | ||
{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_SEP_BAC|FAM.FT.SEP.BAC]] || Bed Nucleus of Anterior Commissure || excitatory-glu || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Septum -> M, abstract)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_SEP_BAC|FAM.FT.SEP.BAC]] || Bed Nucleus of Anterior Commissure || excitatory-glu || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Septum -> M, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFAM_FT_SEP_DBB|FAM.FT.SEP.DBB]] || Diagonal Band of Broca || inhibitory-gaba || [http://www.scholarpedia.org/article/Habenula Habenula Connections (DBB -> MHb)] | + | | || [[BrainRegionFAM_FT_SEP_DBB|FAM.FT.SEP.DBB]] || Diagonal Band of Broca || inhibitory-gaba || uncertain ||[http://www.scholarpedia.org/article/Habenula Habenula Connections (DBB -> MHb)] |
|- | |- | ||
| − | | || [[BrainRegionFAM_FT_SEP_MED|FAM.FT.SEP.MED]] || Medial Septal Nucleus || modulatory-ach || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (MS -> MHb)] | + | | || [[BrainRegionFAM_FT_SEP_MED|FAM.FT.SEP.MED]] || Medial Septal Nucleus || modulatory-ach || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (MS -> MHb)] |
|- | |- | ||
| − | | || [[BrainRegionFAM_FT_SEP_SF|FAM.FT.SEP.SF]] || Septofimbrial Nucleus || inhibitory-gaba || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Septum -> M, abstract)] | + | | || [[BrainRegionFAM_FT_SEP_SF|FAM.FT.SEP.SF]] || Septofimbrial Nucleus || inhibitory-gaba || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Septum -> M, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFAM_FT_SEP_TR|FAM.FT.SEP.TR]] || Triangular Septal Nucleus || inhibitory-gaba || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Septum -> M, abstract)] | + | | || [[BrainRegionFAM_FT_SEP_TR|FAM.FT.SEP.TR]] || Triangular Septal Nucleus || inhibitory-gaba || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (Septum -> M, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || inhibitory-gaba || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> M, abstract)] | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || inhibitory-gaba || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> M, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || modulatory-ne || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB)] | + | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || modulatory-ne || uncertain ||[http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB)] |
|} | |} | ||
| Line 48: | Line 51: | ||
{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (M -> L, abstract)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (M -> L, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || excitatory-glu || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (M -> IPN)] | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || excitatory-glu || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (M -> IPN)] |
|- | |- | ||
| − | | [[BrainAreaTEA|TEA]] || [[BrainRegionTARGET_TEA_ENDOCRINE|TARGET.TEA.ENDOCRINE]] || Endocrine Glands || endocrine-pineal-gland || [http://www.scholarpedia.org/article/Habenula Habenula Connections (MHb -> PB)] | + | | [[BrainAreaTEA|TEA]] || [[BrainRegionTARGET_TEA_ENDOCRINE|TARGET.TEA.ENDOCRINE]] || Endocrine Glands || endocrine-pineal-gland || (none) || [http://www.scholarpedia.org/article/Habenula Habenula Connections (MHb -> PB)] |
|} | |} | ||
Latest revision as of 18:25, 28 April 2019
Medial Habenula
@@Home -> BiologicalLifeResearch -> BrainAreaFAM -> BrainRegionFAM_FD_MHB
This page covers biological details of component Medial Habenula. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Habenula (FAM.FD.HB) -> Medial Habenula (FAM.FD.MHB) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Affective Motivations Area (FAM)
- Area circuit: Reward Emotions Control (FAMXREC)
- Role: processor.affective
- Function: Encoding negative feedback, indirect
- Notes to function:
- affects VTA, dorsal raphe but via interpeduncular nucleus
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FT.SEP.BAC | Bed Nucleus of Anterior Commissure | excitatory-glu | uncertain | Connectivity map of the habenula (Septum -> M, abstract) |
| FAM.FT.SEP.DBB | Diagonal Band of Broca | inhibitory-gaba | uncertain | Habenula Connections (DBB -> MHb) | |
| FAM.FT.SEP.MED | Medial Septal Nucleus | modulatory-ach | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (MS -> MHb) | |
| FAM.FT.SEP.SF | Septofimbrial Nucleus | inhibitory-gaba | uncertain | Connectivity map of the habenula (Septum -> M, abstract) | |
| FAM.FT.SEP.TR | Triangular Septal Nucleus | inhibitory-gaba | uncertain | Connectivity map of the habenula (Septum -> M, abstract) | |
| FEC | FEC.FT.ACC.SH | Nucleus Accumbens Shell | inhibitory-gaba | uncertain | Connectivity map of the habenula (NAc -> M, abstract) |
| LMC | LMC.HT.LC | Locus Coeruleus | modulatory-ne | uncertain | Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.FD.LHB.MED | Lateral Habenula Medial Part | excitatory-glu | uncertain | Connectivity map of the habenula (M -> L, abstract) |
| FEC | FEC.HT.TG.IPD | Interpeduncular Nucleus | excitatory-glu | uncertain | Connectivity map of the habenula (M -> IPN) |
| TEA | TARGET.TEA.ENDOCRINE | Endocrine Glands | endocrine-pineal-gland | (none) | Habenula Connections (MHb -> PB) |
Thirdparty Circuits
(generated)
- Habenula Connections - see Reference (CF.HB-CONNECTIONS)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) IP=Interpeduncular Nucleus,FEC.HT.TG.IPD LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO MHb=Medial Habenula,FAM.FD.MHB MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC PB=Endocrine Glands,TARGET.TEA.ENDOCRINE S=Septal Nuclei,FAM.FT.SEP SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT VTA=Ventral Tegmental Area,LMC.MM.VTA
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
- Exploring role of habenula in emotional behaviors - see Reference (CF.ZEBRAFISH)
LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) MHb=Medial Habenula,FAM.FD.MHB
- Contribution of nAChR subunits to nicotine withdrawal symptoms - see Reference (CF.HB-NICOTINE)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LC=Locus Coeruleus,LMC.HT.LC LHB=Lateral Habenula,FAM.FD.LHB (see Habenula) MHB=Medial Habenula,FAM.FD.MHB
- Both LHb and MHb control the dopaminergic and serotonergic systems - see Reference (CF.HB-DA5HT)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO LS=Lateral Septal Nucleus,FAM.FT.SEP.LT MHb=Medial Habenula,FAM.FD.MHB MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) MS=Medial Septal Nucleus,FAM.FT.SEP.MED PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei) RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Connectivity of dorsal diencephalic conduction system - see Reference (CF.HB-ASYMM)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) MHb=Medial Habenula,FAM.FD.MHB
References
(generated)
- http://www.scholarpedia.org/article/Habenula
- http://jn.physiology.org/content/107/10/2633
- http://dgr.brain.riken.jp/AsymmetryE.html
- http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html
- http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
- http://rstb.royalsocietypublishing.org/content/364/1519/1005
