BrainRegionLLC HT CR DN
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Dentate Nucleus
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This page covers biological details of component Dentate Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Hindbrain Metencephalon -> Cerebellar Complex (LLC.HT.CRC) -> Deep Cerebellar Nuclei (LLC.HT.CR.DCN) -> Dentate Nucleus (LLC.HT.CR.DN) (see Mind Maps)
- Type: nucleus
- Brain area: Lower Brain - Locomotion Control Area
- Role: processor.automatic
- Function: planning, initiation and control of voluntary movements
- Notes to function: dorsal - movement of skeletal muscle, ventral - conscious thought and visuospatial function
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Components
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Component items:
- Amiculum of Dentate Nucleus
- Hilum of Dentate Nucleus
- Neodentate Part of Dentate Nucleus
- Paleodentate of Dentate Nucleus
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| LLC | LLC.HT.CR.CC | Cerebellar Lateral Lobe | inhibitory-gaba | Cerebellum functional divisions (CRP -> DN) |
| LLC.HT.PN.RSP | Rostral Pontine Nucleus | excitatory-glu | Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| LLC | LLC.HT.CR.GN | Globose Nucleus | excitatory-glu | (unknown reference) |
| LLC.MM.RD | Red Nucleus | excitatory-glu | Motor neurons control (LT -> RD) | |
| NCP | NCP.FD.TH.RIL | Rostral Intralaminar Nuclear Group of Thalamus | excitatory-glu | (unknown reference) |
| NDM | NDM.NC.AL.DLPFCL | Lateral Mid-Dorsolateral Prefrontal Cortex | excitatory-glu | (unknown reference) |
| NMA | NMA.FD.TH.VL | Ventral Lateral Nucleus | excitatory-glu | Thalamocortical relationships (s1VL -> VL) |
Thirdparty Circuits
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- Motor neurons control - see Reference (CM.CR-MN)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) CTX=Anterior Lobe,NC.LOBE.ANT EAMN=Anterior/Ventral Horn,SC.VH EGMN=Anterior/Ventral Horn,SC.VH FAMN=Anterior/Ventral Horn,SC.VH FG=Fastigual Nucleus,LRC.HT.CR.FG IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex) LT=Dentate Nucleus,LLC.HT.CR.DN MRF=Medullary Reticular Formation,HL.RF PRF=Pontine Reticular Formation,HT.RF RD=Red Nucleus,LLC.MM.RD VB=Vestibular Nuclei,LPC.HT.VBN
- Thalamocortical relationships - see Reference (CL.THALAMUS-PROJECTIONS)
A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MGN=Medial Geniculate Body,NSA.FD.TH.MGB P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus) VA=Ventral Anterior Nucleus,NMA.FD.TH.VA VL=Ventral Lateral Nucleus,NMA.FD.TH.VL VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia) pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) pLGN=Primary Visual Cortex,NSA.NC.OCC.V1 pLP=Superior Parietal Lobule,NC.SPL pMD=Prefrontal Cortex,NC.AL.PFC pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1 pP=Insular Cortex,NC.INS pVA=Supplementary Motor Cortex,NMA.NC.SMC pVL=Motor Cortex,NMA.NC.MC pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1 pVPM=Precentral Cortex,NCP.NC.PO.PCC s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) s1MD=Septal Nuclei,FAM.FT.SEP s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV s1VL=Dentate Nucleus,LLC.HT.CR.DN s2A=Mammillary Body,FD.MB (see Hypothalamus) s2MD=Piriform Cortex,NSA.NC.PH.PIR s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR s2VL=Basal Ganglia,FEC.FT.BG s3MD=Prefrontal Cortex,NC.AL.PFC sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) sLD=Superior Parietal Lobule,NC.SPL sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) sVA=Basal Ganglia,FEC.FT.BG sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn) sVPM=Solitary Nucleus,LPC.HL.SOL
- Cerebellum functional divisions - see Reference (CM.CR-DECUSSATION)
CCV=Central Cervical Nucleus,LPC.SC.IZ.CCV CRP=Cerebellar Lateral Lobe,LLC.HT.CR.CC CRS=Cerebellar Paravermis,LLC.HT.CR.PV CRV=Cerebellar Vermis,LRC.HT.CR.VM CTX=Anterior Lobe,NC.LOBE.ANT DN=Dentate Nucleus,LLC.HT.CR.DN FG=Fastigual Nucleus,LRC.HT.CR.FG IO=Inferior Olivary Nucleus,LLC.HL.IO IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex) LT=Dentate Nucleus,LLC.HT.CR.DN PNN=Basilar Pontine Nuclei,LLC.HT.BPN RD=Red Nucleus,LLC.MM.RD RF=Pontine Reticular Formation,HT.RF SCM=Anterior/Ventral Horn,SC.VH SCS=Proprius Nucleus,LPC.SC.PH.NP SCSD=Clarke Nucleus,LPC.SC.PH.CL VB=Vestibular Nuclei,LPC.HT.VBN VBG=Vestibular Ganglion,LPC.PN.SG.VB VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
References
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