BrainRegionFMM NC PH PRS
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Presubiculum
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This page covers biological details of component Presubiculum. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> Retrosubicular Area (FMM.NC.PHA.RS) -> Presubiculum (FMM.NC.PH.PRS) (see Mind Maps)
- Type: cortex
- Brain area: Forebrain - Memory Management Area
- Brodmann ID: 27
- Role: cortex.orienting
- Function: Path integration, head direction
- Notes to structure: close to Subicular Complex
- Notes to function: Major projects to ET, from TH.LD
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | excitatory-glu | Detailed amygdalohippocampal projections (Bpc -> PrS) |
| FMM | FMM.FD.TH.AV | Anteroventral Nucleus | excitatory-glu | (unknown reference) |
| FMM.FT.HF.SUBD | Distal Subiculum | excitatory-glu | Attractor Network in Hippocampus (SUB -> PRESUB, abstract) | |
| NCP | NCP.NC.INS.PPC | Peripaleocortical Claustral | feedforward-glu | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FMM | FMM.FD.MB.LMB | Lateral Mammillary Nucleus | excitatory-glu | Mammillary bodies: two memory systems in one (PRS -> LMB) |
| FMM.FD.MB.MMB | Medial Mammillary Nucleus | excitatory-glu | Attractor Network in Hippocampus (PRESUB -> MBIN) | |
| FMM.FD.TH.LD | Lateral Dorsal Nucleus of Thalamus | excitatory-glu | Contributions of Diencephalon to Recognition Memory (Presub -> LD) | |
| FMM.NC.PH.MEC | Medial Entorhinal Cortex | feedforward-glu | Attractor Network in Hippocampus (PRESUB -> EC, abstract) | |
| NPE | NPE.FD.TH.MPV | Medial Pulvinar | excitatory-glu | Contributions of Diencephalon to Recognition Memory (Presub -> mPULV) |
Thirdparty Circuits
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- Contributions of Diencephalon to Recognition Memory - see Reference (CT.RECOGNITION-MEMORY)
AD=Anterodorsal Nucleus,FMM.FD.TH.AD AM=Anteromedial Nucleus,NCP.FD.TH.AM AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) AV=Anteroventral Nucleus,FMM.FD.TH.AV CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB MDmc=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MID=Midline Nuclear Group of Thalamus,FD.TH.MTH (see Cognitive Thalamus) MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) Parasub=Parasubiculum,FMM.NC.PH.PAS Perirhinal=Perirhinal Cortex,FMM.NC.PH.PER PostCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Presub=Presubiculum,FMM.NC.PH.PRS Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) SubPrePara=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) mPULV=Medial Pulvinar,NPE.FD.TH.MPV
- Mammillary bodies: two memory systems in one - see Reference (CT.MB-MEMORY)
ADTH=Anterodorsal Nucleus,FMM.FD.TH.AD AMTH=Anteromedial Nucleus,NCP.FD.TH.AM AVTH=Anteroventral Nucleus,FMM.FD.TH.AV DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) PAS=Parasubiculum,FMM.NC.PH.PAS POS=Postsubiculum,FMM.NC.PH.POS PRS=Presubiculum,FMM.NC.PH.PRS SEP=Septal Nuclei,FAM.FT.SEP SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) SupraMM=Supramammillary Nucleus,LAC.FD.HT.SUM TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see Hypothalamus) VTN=Ventral Tegmental Area,LMC.MM.VTA
- Attractor Network in Hippocampus - see Reference (CT.ATTRACTOR-NETWORK)
AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) MBIN=Medial Mammillary Nucleus,FMM.FD.MB.MMB MBOUT=Lateral Mammillary Nucleus,FMM.FD.MB.LMB NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PERI=Perirhinal Cortex,FMM.NC.PH.PER PRESUB=Presubiculum,FMM.NC.PH.PRS SEP=Septal Nuclei,FAM.FT.SEP SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
- Flow of impulses in hippocampal region - see Reference (CT.CA2)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA2=Dorsolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA2 CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG ENT=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) PRES=Presubiculum,FMM.NC.PH.PRS SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
- Detailed amygdalohippocampal projections - see Reference (CF.AM-HC-DET)
ABmg=Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB Bmg=Magnocellular Basal Amygdaloid Nucleus,FAM.FT.AM.BM Bpc=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP CA1D=Distal CA1 of Hippocampus,FMM.FT.HC.CA1D CA1P=Proximal CA1 of Hippocampus,FMM.FT.HC.CA1P L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala) PaS=Parasubiculum,FMM.NC.PH.PAS PrS=Presubiculum,FMM.NC.PH.PRS
References
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