BrainAreaLLC

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Locomotion Control Area

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Local Circuits

(generated)

ID Name Regions
LGP Gait and Posture Control LLC.MM.CNF, LLC.MM.SCNF
LLC Cerebrocerebellar Locomotion LLC.HP.CR.CC, LLC.HP.CR.DN, LLC.HP.PN.RP, LLC.HP.PRF.PDT
LLL Spinocerebellar Learning LLC.FD.TH.SF, LLC.HM.ARC, LLC.HM.IO, LLC.HM.RF.MLRN, LLC.HM.RF.PLRN, LLC.HP.PN.PBB
LLP Vestibulocerebellar Locomotion LLC.HM.RF.SLRN, LLC.HP.CR.FN, LLC.HP.CR.VC, LLC.SC.IZ.CCV
LLS Spinocerebellar Locomotion LLC.HP.CR.EN, LLC.HP.CR.GN, LLC.HP.CR.SC, LLC.MM.RD

Gait and Posture Control

unavailable

Component ID Component Name Type Service Function Comments
LLC.MM.CNF Cuneiform Nucleus nucleus LLE Passive coping strategy to novel, painful or threatening stimuli modulatory nucleus; medial part of midbrain RF
LLC.MM.SCNF Subcuneiform Nucleus nucleus LLE Initiation of gait, feedback control of saccade accuracy contributes to generation of estimate of target or
eye position coded in craniotopic coordinates

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Subcortical
LPC LLC.MM.CNF LPC.SC.PH.CL Clarke Nucleus nucleus-nucleus (unknown reference)
LRC LLC.MM.SCNF LRC.HM.NPH Prepositus Nucleus nucleus-nucleus (unknown reference)
LRC.HP.PRF.GCR Gigantocellular Reticular Nucleus nucleus-nucleus (unknown reference)
LRC.MM.RP.RIP Raphe Interpositus Nucleus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
LAC LLC.MM.CNF LAC.HM.VGN Vagus Nucleus nucleus-nucleus (unknown reference)
LMC LLC.MM.SCNF LMC.HM.RP.MG Raphe Magnus Nucleus nucleus-nucleus (unknown reference)
LMC.HP.RP.PRN Pontine Raphe Nucleus nucleus-nucleus (unknown reference)
LRC LLC.MM.CNF LRC.HP.PN.KFN Kolliker-Fuse Nucleus nucleus-nucleus (unknown reference)
LRC.HP.PRF.GCR Gigantocellular Reticular Nucleus nucleus-nucleus (unknown reference)

Cerebrocerebellar Locomotion

unavailable

Component ID Component Name Type Service Function Comments
LLC.HP.CR.CC Cerebrocerebellum cortex LLC planning movement that is about to occur, evaluating sensory information for
action, handles intentions
lateral zone of anterior and posterior lobes;
dentate nucleus; receives input exclusively from
cerebral cortex (especially parietal lobe) via
pontine nuclei (forming cortico-ponto-cerebellar
pathways), and sends output mainly to ventrolateral
thalamus and to red nucleus; add skill to movements
LLC.HP.CR.DN Dentate Nucleus nucleus LLC planning, initiation and control of voluntary movements dorsal - movement of skeletal muscle, ventral -
conscious thought and visuospatial function
LLC.HP.PN.RP Rostral Pontine Nucleus nucleus LLI Part of learning, motivation, spatial memory pathway Relay from mammillary body to CR
LLC.HP.PRF.PDT Pontine Reticulotegmental Nucleus nucleus LLI Mediate saccadic eye movements Inactivation leads to deficit of expression, but
not learning

Internal Region Connections:

Source Region Target Region Type Reference
LLC.HP.CR.CC LLC.HP.CR.DN allocortex-nucleus-gaba (unknown reference)
LLC.HP.PN.RP LLC.HP.CR.DN nucleus-nucleus (unknown reference)
LLC.HP.PRF.PDT LLC.HP.CR.CC nucleus-allocortex (unknown reference)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NDM LLC.HP.PRF.PDT NDM.NC.AL.VACG Ventral Anterior Cingulate Area neocortex-nucleus Vocal Control (Premotor24 -> RF, abstract)
NMA LLC.HP.PRF.PDT NMA.NC.MC Motor Cortex neocortex-nucleus Global visual system (FrontalCortex -> RF, abstract)
NMA.NC.SMC.F3 Supplementary Motor Area neocortex-nucleus Vocal Control (M2 -> RF, abstract)
NPE LLC.HP.PRF.PDT NPE.NC.BRA.PO Broca's Area Pars Opercularis neocortex-nucleus Vocal Control (Broca -> RF, abstract)
Subcortical
FMM LLC.HP.PN.RP FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus Prefrontal Cortex (PFC) in emotional behavior (HT -> PN, abstract)
LLC.HP.PRF.PDT FMM.FD.MB.LMB Lateral Mammillary Nucleus nucleus-nucleus Mammillary Body (LMB -> RTG)
FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus Mammillary Body (MMB -> RTG)
LAC LLC.HP.PN.RP LAC.FD.HT.RCH Retrochiasmatic Nucleus nucleus-nucleus Prefrontal Cortex (PFC) in emotional behavior (HT -> PN, abstract)
LRC LLC.HP.CR.CC LRC.HP.PRF.RPO Oral Pontine Reticular Nucleus nucleus-allocortex Saccades and smooth movements (DLPN -> CR, abstract)
LLC.HP.PRF.PDT LRC.MM.SC.DEEP Deep Superior Colliculus nucleus-nucleus Geniculate and Extyrageniculate Paths (SC -> RF, abstract)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Cortical
NDM LLC.HP.CR.DN NDM.NC.AL.DLPFCL Lateral Mid-Dorsolateral Prefrontal Cortex nucleus-neocortex (unknown reference)
NMA LLC.HP.CR.DN NMA.FD.TH.VL Ventral Lateral Nucleus nucleus-nucleus (unknown reference)
Subcortical
FEC LLC.HP.CR.DN FEC.FD.TH.RIL Rostral Intralaminar Nuclear Group of Thalamus nucleus-nucleus (unknown reference)
LLC LLC.HP.CR.DN LLC.HP.CR.GN Globose Nucleus nucleus-nucleus (unknown reference)

Spinocerebellar Learning

unavailable

Component ID Component Name Type Service Function Comments
LLC.FD.TH.SF Subfascicular Nucleus of Thalamus nucleus LUS Relays from PAG to Rhape nuclei, Inferior olive nucleus
LLC.HM.ARC Arcuate Nucleus of Medulla nucleus LLI Relay cardiorepriratory proprioception to cerebellum Receives fibers from spinothalamic tract and sends
to CR; controlling respiratory frequency;
chemosensitivity and cardiorespiratory activity
LLC.HM.IO Inferior Olivary Nucleus nucleus LLI Proprioception Relay from Spinal Cord to Cerebellum
LLC.HM.RF.MLRN Lateral Reticular Nucleus, Magnocellular nucleus LLI spinal cord projections to cerebellum, cervical from RD; medial, magnocellular portion, immediately
adjacent to lateral - to vermis; rest of
magnocellular subnucleus sends its projections to
hemisphere regions of cerebellum
LLC.HM.RF.PLRN Lateral Reticular Nucleus, Parvocellular nucleus LLI spinal cord projections to cerebellum, thoracolumbar from RD; lateral, parvocellular portion of LRN send
most their projections to vermis of cerebellum
LLC.HP.PN.PBB Pontobulbar Body nucleus LLI Relay neck proprioception to cerebellum Walking, speaking, breathing, part of
corticopontocerebellar pathway

Internal Region Connections:

Source Region Target Region Type Reference
LLC.FD.TH.SF LLC.HM.IO nucleus-nucleus-gaba (unknown reference)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NMA LLC.HP.PN.PBB NMA.NC.MC Motor Cortex neocortex-nucleus Prefrontal Cortex (PFC) in motor behavior (MC -> PN, abstract)
Subcortical
LLC LLC.HM.IO LLC.MM.RD Red Nucleus nucleus-nucleus (unknown reference)
LLC.SC.IZ.CCV Central Cervical Nucleus nucleus-nucleus (unknown reference)
LLC.HM.RF.MLRN LLC.MM.RD Red Nucleus nucleus-nucleus (unknown reference)
LLC.HM.RF.PLRN LLC.MM.RD Red Nucleus nucleus-nucleus (unknown reference)
LMC LLC.FD.TH.SF LMC.MM.PAG Periaqueductal Gray Matter nucleus-nucleus-ENK (unknown reference)
LPC LLC.HM.ARC LPC.SC.PH.CL Clarke Nucleus nucleus-nucleus (unknown reference)
LLC.HM.IO LPC.SC.PH.NP Proprius Nucleus nucleus-nucleus (unknown reference)
LLC.HM.RF.PLRN LPC.SC.IZ.IMM Intermediomedial Nucleus nucleus-nucleus (unknown reference)
LLC.HP.PN.PBB LPC.SC.PH.CL Clarke Nucleus nucleus-nucleus (unknown reference)
LRC LLC.HM.IO LRC.MM.DSCH Darkschewitsch Nucleus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
LLC LLC.HM.ARC LLC.HP.CR.SC Spinocerebellum nucleus-allocortex (unknown reference)
LLC.HM.IO LLC.HP.CR.GN Globose Nucleus nucleus-nucleus (unknown reference)
LLC.HP.CR.SC Spinocerebellum nucleus-allocortex (unknown reference)
LLC.HM.RF.MLRN LLC.HP.CR.SC Spinocerebellum nucleus-allocortex (unknown reference)
LLC.HM.RF.PLRN LLC.HP.CR.SC Spinocerebellum nucleus-allocortex (unknown reference)
LLC.HP.PN.PBB LLC.HP.CR.SC Spinocerebellum nucleus-allocortex Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)
LMC LLC.FD.TH.SF LMC.MM.RP.DRN Dorsal Raphe Nucleus nucleus-nucleus-gaba (unknown reference)

Vestibulocerebellar Locomotion

unavailable

Component ID Component Name Type Service Function Comments
LLC.HM.RF.SLRN Lateral Reticular Nucleus, Subtrigeminal nucleus LLI vestibular input from lateral vestibular nucleus to
vestibulocerebellum
LLC.HP.CR.FN Fastigual Nucleus nucleus LLC rostral - interprets body motion and places it on spatial planes to estimate
movement of body through space; caudal - saccadic eye movements
LLC.HP.CR.VC Vestibulocerebellum cortex LLC balance and spatial orientation, gait projects to vestibular nuclei only; equilibrium;
tunes balance (stance and gait) and VOR
LLC.SC.IZ.CCV Central Cervical Nucleus nucleus LLI Coordinate voluntary movements, maintain balance, and learn motor skills Receive neck and vestibular input and project to CR
and vestibular nuclei

Internal Region Connections:

Source Region Target Region Type Reference
LLC.HM.RF.SLRN LLC.HP.CR.VC nucleus-allocortex (unknown reference)
LLC.HP.CR.VC LLC.HP.CR.FN allocortex-nucleus-gaba (unknown reference)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Subcortical
LPC LLC.HM.RF.SLRN LPC.HP.LVBN Lateral Vestibular Nuclei nucleus-nucleus (unknown reference)
LLC.HP.CR.VC LPC.HP.IVBN Inferior Vestibular Nuclei nucleus-allocortex (unknown reference)
LPC.HP.MVBN Medial Vestibular Nucleus nucleus-allocortex (unknown reference)
LLC.SC.IZ.CCV LPC.PN.SG.UDRG Upper Dorsal Root Ganglion ganglion-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Cortical
NSA LLC.SC.IZ.CCV NSA.FD.TH.VPL Ventral Posterolateral Nucleus nucleus-nucleus Thalamocortical relationships (s1P -> P, abstract)
Subcortical
FEC LLC.SC.IZ.CCV FEC.FD.TH.RIL Rostral Intralaminar Nuclear Group of Thalamus nucleus-nucleus (unknown reference)
LLC LLC.SC.IZ.CCV LLC.HM.IO Inferior Olivary Nucleus nucleus-nucleus (unknown reference)
LPC LLC.HP.CR.FN LPC.HP.LVBN Lateral Vestibular Nuclei nucleus-nucleus (unknown reference)
LLC.SC.IZ.CCV LPC.HP.IVBN Inferior Vestibular Nuclei nucleus-nucleus (unknown reference)
LRC LLC.HP.CR.FN LRC.HP.PRF.CRF Caudal Pontine Reticular Nucleus nucleus-nucleus (unknown reference)
LRC.MM.PT.PR Principal Pretectal Nucleus nucleus-nucleus (unknown reference)
LRC.MM.SC.INT Intermediate Superior Colliculus nucleus-nucleus (unknown reference)

Spinocerebellar Locomotion

unavailable

Component ID Component Name Type Service Function Comments
LLC.HP.CR.EN Emboliform Nucleus nucleus LLC Modulate motor functions of Red Nucleus Trigeminocerebellar tract
LLC.HP.CR.GN Globose Nucleus nucleus LLC Modulate motor functions of Red Nucleus
LLC.HP.CR.SC Spinocerebellum cortex LLC fine-tune body and limb movements medial zone of anterior and posterior lobes;
fastigial and interpositus nuclei; tunes and
adjusts ongoing movements and muscle tone
LLC.MM.RD Red Nucleus nucleus LLE Motor coordination Crawling of babies is controlled by RN

Internal Region Connections:

Source Region Target Region Type Reference
LLC.HP.CR.EN LLC.HP.CR.GN nucleus-nucleus (unknown reference)
LLC.MM.RD nucleus-nucleus (unknown reference)
LLC.HP.CR.GN LLC.MM.RD nucleus-nucleus (unknown reference)
LLC.HP.CR.SC LLC.HP.CR.EN allocortex-nucleus-gaba (unknown reference)
LLC.HP.CR.GN allocortex-nucleus-gaba (unknown reference)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NDM LLC.MM.RD NDM.NC.AL.VACG Ventral Anterior Cingulate Area neocortex-nucleus (unknown reference)
Subcortical
FEC LLC.MM.RD FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral nucleus-nucleus-DA (unknown reference)
LLC LLC.HP.CR.GN LLC.HM.IO Inferior Olivary Nucleus nucleus-nucleus (unknown reference)
LLC.HP.CR.DN Dentate Nucleus nucleus-nucleus (unknown reference)
LLC.HP.CR.SC LLC.HM.ARC Arcuate Nucleus of Medulla nucleus-allocortex (unknown reference)
LLC.HM.IO Inferior Olivary Nucleus nucleus-allocortex (unknown reference)
LLC.HM.RF.MLRN Lateral Reticular Nucleus, Magnocellular nucleus-allocortex (unknown reference)
LLC.HM.RF.PLRN Lateral Reticular Nucleus, Parvocellular nucleus-allocortex (unknown reference)
LLC.HP.PN.PBB Pontobulbar Body nucleus-allocortex Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)
LMC LLC.HP.CR.SC LMC.HM.RP.OB Raphe Obscurus Nucleus nucleus-allocortex-5HT (unknown reference)
LMC.HP.RP.PRN Pontine Raphe Nucleus nucleus-allocortex-5HT (unknown reference)
LPC LLC.HP.CR.SC LPC.HM.ACU Accessory Cuneate Nucleus nucleus-allocortex (unknown reference)
LPC.HM.CU Cuneate Nucleus nucleus-allocortex (unknown reference)
LPC.SC.IZ.CBS Centrobasalis Nucleus nucleus-allocortex (unknown reference)
LPC.SC.IZ.IMM Intermediomedial Nucleus nucleus-allocortex (unknown reference)
LPC.SC.PH.CL Clarke Nucleus nucleus-allocortex (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FEC LLC.HP.CR.EN FEC.FD.TH.CM Centromedian Nucleus of Thalamus nucleus-nucleus (unknown reference)
LLC LLC.MM.RD LLC.HM.IO Inferior Olivary Nucleus nucleus-nucleus (unknown reference)
LLC.HM.RF.MLRN Lateral Reticular Nucleus, Magnocellular nucleus-nucleus (unknown reference)
LLC.HM.RF.PLRN Lateral Reticular Nucleus, Parvocellular nucleus-nucleus (unknown reference)
LPC LLC.MM.RD LPC.SC.VH.PL Posterolateral Nucleus nucleus-nucleus (unknown reference)
LPC.SC.VH.PM Posteromedial Nucleus nucleus-nucleus (unknown reference)
LRC LLC.HP.CR.GN LRC.MM.DSCH Darkschewitsch Nucleus nucleus-nucleus (unknown reference)
LRC.MM.SC.DEEP Deep Superior Colliculus nucleus-nucleus (unknown reference)

Thirdparty Circuits

(generated)

unavailable

unavailable

unavailable


References

(generated)