BrainCenterHT RF

Pontine Reticular Formation

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This page covers biological details of component group Pontine Reticular Formation. Component group is part of aHuman target integrated biological model.

• Top-down path to center: Hindbrain Metencephalon -> Pontine Reticular Formation (HT.RF) (see Mind Maps)
• Function:

(generated)

Components

(generated)

Component items:

• Pontine Reticular Formation, Midline Column (HT.RF.MID)
  • Raphe Nuclei of Pons (HT.RF.MID.RP)
    • Pontine Raphe Nucleus (LMC.HP.RP.PRN): Regulation of sleep cycle
• Pontine Reticular Formation, Medial Column (HT.RF.MED)
  • Paramedian Pontine Reticular Formation (HT.PRF.PPRF)
    • Oral Pontine Reticular Nucleus (LRC.HT.PRF.RPO): Mediation of changing to and from REM sleep
    • Caudal Pontine Reticular Nucleus (LRC.HT.PRF.CRF): Mediate head movements
    • Parvocellular Reticular Nucleus (LRC.HT.PRF.PVR): Flow of respiratory current out of organism
• Pontine Reticular Formation, Lateral Column (HT.RF.LAT)
  • Pontine Reticulotegmental Nucleus (LLC.HT.PRF.PDT): Mediate saccadic eye movements
  • Parabrachial Nucleus (LPC.HT.PRF.PB): Source of short-latency nociceptive input; sense of physiological condition of body well-being or interoception

Connectivity

(generated)

Internal Regions Connections:

• no connections

External Connections:

External Inbound Center Connections:

Source Center	Sample Link	Reference
Central Extended Amygdala (FAM.FT.CEAM)	FAM.FT.IPAC.MED -> LPC.HT.PRF.PB	(unknown reference)
Hypothalamus (FD.HT)	FMM.FD.MB.LMB -> LLC.HT.PRF.PDT	Mammillary Body (LMB -> RTG)
Basal Ganglia (FEC.FT.BG)	FEC.FT.SNC.MED -> LRC.HT.PRF.PVR	(unknown reference)
Myelencephalic Sensory Nuclei (HL.SN)	LPC.HL.TGS.STR -> LLC.HT.PRF.PDT	Eye blink reflex and pupillary light reflex (SpinalTrigeminal -> RF, abstract)
Cerebellar Complex (LLC.HT.CRC)	LLC.HT.CR.FN -> LRC.HT.PRF.CRF	(unknown reference)
Vestibular Nuclei (LPC.HT.VBN)	LPC.HT.IVBN -> LRC.HT.PRF.CRF	Vestibulo-ocular reflex (VOR) (VestibularNuclei -> PPRF, abstract)
Reflexes Nuclei of Midbrain Mesencephalon (MM.REF)	LRC.MM.SC.DEEP -> LLC.HT.PRF.PDT	Geniculate and Extyrageniculate Paths (SC -> RF, abstract)
Mesencephalic Reticular Formation (MM.RF)	LLC.MM.SCNF -> LMC.HP.RP.PRN	(unknown reference)
Anterior Cingulate Area (NC.ACG)	NDM.NC.AL.VACG -> LLC.HT.PRF.PDT	Motor neurons control (CTX -> PRF, abstract)
Lateral Prefrontal Cortex (NC.AL.LPFC)	NPE.NC.BRA.PO -> LLC.HT.PRF.PDT	Motor neurons control (CTX -> PRF, abstract)
Premotor Cortex (NC.PMC)	NMA.NC.PMC.AFEF -> LRC.HT.PRF.RPO	Motor neurons control (CTX -> PRF, abstract)
Motor Cortex (NMA.NC.MC)	NMA.NC.MC -> LLC.HT.PRF.PDT	Motor neurons control (CTX -> PRF, abstract)
Supplementary Motor Cortex (NMA.NC.SMC)	NMA.NC.SMC.F3 -> LLC.HT.PRF.PDT	Motor neurons control (CTX -> PRF, abstract)
Inferotemporal Area (NSA.NC.IT)	NSA.NC.IT.TE -> LRC.HT.PRF.RPO	Saccades and smooth movements (TEF -> DLPN, abstract)

External Outbound Center Connections:

Target Center	Sample Link	Reference
Amygdala (FAM.FT.AM)	LPC.HT.PRF.PB -> FAM.FT.AM.CEL	Amygdalar disruption of prefrontal cortex (PB -> AM, abstract)
Hypothalamus (FD.HT)	LPC.HT.PRF.PB -> LAC.FD.HT.DM	Food-entrainable circadian oscillator (PBN -> DMH)
Sensory Thalamus (FD.TH.SR)	LPC.HT.PRF.PB -> NSA.FD.TH.VPI	(unknown reference)
Basal Ganglia (FEC.FT.BG)	LPC.HT.PRF.PB -> FEC.FT.ACC.SH	Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)
Myelencephalic Motor Nuclei (HL.MN)	LRC.HT.PRF.CRF -> LPC.HL.AMB	Vocal Control (RF -> NucleusAmbiguus, abstract)
Myelencephalic Parasympathetic Nuclei (HL.PSN)	LPC.HT.PRF.PB -> LAC.HL.VGN	Physiology and pathophysiology of lower urinary tract (PBN -> DVM)
Metencephalic Motor Nuclei (HT.MN)	LRC.HT.PRF.CRF -> LPC.HT.FCM	Vocal Control (RF -> MotorVII, abstract)
Pontine Tegmental Nuclei (HT.TG)	LRC.HT.PRF.RPO -> FAM.HT.TG.NI	(unknown reference)
Cerebellar Complex (LLC.HT.CRC)	LLC.HT.PRF.PDT -> LLC.HT.CR.CC	(unknown reference)
Abducens Nucleus (LPC.HT.ABD)	LRC.HT.PRF.RPO -> LPC.HT.ABD	Vestibulo-ocular reflex (VOR) (PPRF -> Abducens, abstract)
Vestibular Nuclei (LPC.HT.VBN)	LRC.HT.PRF.RPO -> LPC.HT.IVBN	(unknown reference)
Perhipheral Nuclei of Midbrain Mesencephalon (MM.PER)	LRC.HT.PRF.RPO -> LPC.MM.OCN	Global visual system (RF -> OPN, abstract)
Insular Cortex (NC.INS)	LPC.HT.PRF.PB -> NCP.NC.INS.PIC	Gustatory sensory system of rat and macaque (PB -> Gud, abstract)
Anterior/Ventral Horn (SC.VH)	LRC.HT.PRF.RPO -> LPC.SC.VH.SAN	Motor neurons control (PRF -> EGMN, abstract)