Difference between revisions of "BrainRegionFEC FT ACC CORE"
From aHuman Wiki
(Automated page entry using MWPush.pl) |
(Automated page entry using MWPush.pl) |
||
| (10 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
| − | |||
<pre style="color: green">Nucleus Accumbens Core</pre> | <pre style="color: green">Nucleus Accumbens Core</pre> | ||
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_ACC_CORE]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_ACC_CORE]] | ||
| Line 9: | Line 8: | ||
* '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> [[BrainRegionFEC_FT_ACC_CORE|Nucleus Accumbens Core]] (FEC.FT.ACC.CORE) (see [[OverallMindMaps|Mind Maps]]) | * '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> [[BrainRegionFEC_FT_ACC_CORE|Nucleus Accumbens Core]] (FEC.FT.ACC.CORE) (see [[OverallMindMaps|Mind Maps]]) | ||
* '''Type''': nucleus | * '''Type''': nucleus | ||
| − | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] | + | * '''Quality''': L0 |
| − | * '''Role''': | + | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] (FEC) |
| + | * '''Area circuit''': Motor Motivational Salience (FECLM) | ||
| + | * '''Role''': basal.ganglia.striatum | ||
* '''Function''': cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future | * '''Function''': cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future | ||
(generated) | (generated) | ||
| Line 28: | Line 29: | ||
{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_TH_PT|FAM.FD.TH.PT]] || Paratenial Nucleus of Thalamus || excitatory-glu || (unknown reference) | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_TH_PT|FAM.FD.TH.PT]] || Paratenial Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> NACC, abstract)] | + | | || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || uncertain ||[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> NACC, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_TH_RH|FMM.FD.TH.RH]] || Rhomboidal Nucleus of Thalamus || excitatory-glu || (unknown reference) | + | | [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_TH_RH|FMM.FD.TH.RH]] || Rhomboidal Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionFMM_FT_HC_CA1D|FMM.FT.HC.CA1D]] || Distal CA1 of Hippocampus || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (CA1 -> NACC, abstract)] | + | | || [[BrainRegionFMM_FT_HC_CA1D|FMM.FT.HC.CA1D]] || Distal CA1 of Hippocampus || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (CA1 -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_FT_HF_SUBD|FMM.FT.HF.SUBD]] || Distal Subiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)] | + | | || [[BrainRegionFMM_FT_HF_SUBD|FMM.FT.HF.SUBD]] || Distal Subiculum || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_FT_HF_SUBP|FMM.FT.HF.SUBP]] || Proximal Subiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)] | + | | || [[BrainRegionFMM_FT_HF_SUBP|FMM.FT.HF.SUBP]] || Proximal Subiculum || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (EC -> NACC, abstract)] | + | | || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (EC -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_NC_PH_PAS|FMM.NC.PH.PAS]] || Parasubiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (PAS -> NACC, abstract)] | + | | || [[BrainRegionFMM_NC_PH_PAS|FMM.NC.PH.PAS]] || Parasubiculum || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (PAS -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_NC_PH_PER|FMM.NC.PH.PER]] || Perirhinal Cortex || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (PRR -> NACC, abstract)] | + | | || [[BrainRegionFMM_NC_PH_PER|FMM.NC.PH.PER]] || Perirhinal Cortex || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (PRR -> NACC, abstract)] |
|- | |- | ||
| − | | [[ | + | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_FD_TH_PV|NDM.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
| − | | | + | | || [[BrainRegionNDM_NC_AL_FPC|NDM.NC.AL.FPC]] || Lateral Frontopolar Cortex || excitatory-glu || uncertain ||[http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (OMPFC -> NACC, abstract)] |
|} | |} | ||
| Line 56: | Line 57: | ||
{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || inhibitory-gaba || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> L, abstract)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || inhibitory-gaba || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> L, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || inhibitory-gaba || (unknown reference) | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || inhibitory-gaba || uncertain || (unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_SNR_MED|FEC.FT.SNR.MED]] || Substantia Nigra Pars Reticulata Medial || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> SNr, abstract)] | + | | || [[BrainRegionFEC_FT_SNR_MED|FEC.FT.SNR.MED]] || Substantia Nigra Pars Reticulata Medial || inhibitory-gaba || uncertain || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> SNr, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_VP_DL|FEC.FT.VP.DL]] || Ventral Pallidum Dorsolateral || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)] | + | | || [[BrainRegionFEC_FT_VP_DL|FEC.FT.VP.DL]] || Ventral Pallidum Dorsolateral || inhibitory-gaba || uncertain || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || inhibitory-gaba || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (NACC -> VTA, abstract)] | + | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || inhibitory-gaba || uncertain || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (NACC -> VTA, abstract)] |
|} | |} | ||
| Line 72: | Line 73: | ||
(generated) | (generated) | ||
| − | * [http://www.nature.com/nrn/journal/v5/n3/images/nrn1345-i1.jpg Saccadic Vision] - see [http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Reference] | + | * [http://www.nature.com/nrn/journal/v5/n3/images/nrn1345-i1.jpg Saccadic Vision] - see [http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Reference] (CP.SACCADIC-VISION) |
| − | <img src="http:// | + | BG=[[BrainCenterFEC_FT_BG|Basal Ganglia,FEC.FT.BG]] |
| + | CN=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | CR=Cerebellum,LLC.HT.CR (see [[BrainCenterLLC_HT_CRC|Cerebellar Complex]]) | ||
| + | FrontalCortex=Anterior Lobe,NC.LOBE.ANT | ||
| + | GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | LGN=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]] | ||
| + | LIP=[[BrainRegionNPE_NC_IPS_LIP|Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP]] | ||
| + | RF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]] | ||
| + | Retina=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]] | ||
| + | SCi=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
| + | SCs=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
| + | SNpr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]] | ||
| + | STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]]) | ||
| + | Thalamus=Thalamus,FD.TH | ||
| + | VisualCortex=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/e149203d6ac92f76e1ccabaef41666a6.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
| − | * [http:// | + | * [http://www.nature.com/nrendo/journal/v6/n8/images/nrendo.2010.93-f1.jpg Bowels control brain: gut hormones and obesity] - see [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Reference] (CP.BOWELS) |
| − | <img src="http:// | + | AMY=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]] |
| + | ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]] | ||
| + | DS=Dorsal Striatum,FEC.FT.DST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
| + | ME=[[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands,TARGET.TEA.ENDOCRINE]] | ||
| + | NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]] | ||
| + | OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
| + | PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]] | ||
| + | PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]] | ||
| + | VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]] | ||
| + | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/1550acf4cfac7352ce9d8ba11a39c4e6.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
| − | * [http://neurowiki2012.wikispaces.com/file/view/Reward_circuit.jpg/315908202/Reward_circuit.jpg Reward circuit of human brain] - see [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reference] | + | * [http://neurowiki2012.wikispaces.com/file/view/Reward_circuit.jpg/315908202/Reward_circuit.jpg Reward circuit of human brain] - see [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reference] (CF.REWARD-CIRCUIT) |
| − | <img src="http:// | + | AM=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]] |
| + | HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
| + | NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | PFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
| + | VPAL=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/284310755a3e65beb74826e15beade5d.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
| − | * [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] | + | * [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN) |
| − | <img src="http:// | + | CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
| + | EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]] | ||
| + | Hippo=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
| + | IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
| + | L=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]]) | ||
| + | LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
| + | M=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
| + | NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]] | ||
| + | Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]]) | ||
| + | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | Septum=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]] | ||
| + | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
| − | * [http://www.impulsecontroldisorders.org/images/8-Urges9proof.jpg Craving] - see [http://www.impulsecontroldisorders.org/html/cravings.html Reference] | + | * [http://www.impulsecontroldisorders.org/images/8-Urges9proof.jpg Craving] - see [http://www.impulsecontroldisorders.org/html/cravings.html Reference] (CF.CRAVING) |
| − | <img src="http:// | + | NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
| + | OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
| + | SNr=[[BrainRegionFEC_FT_SNR_MED|Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED]] | ||
| + | VPAL=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/03180da352394bdd7711e289118a3d96.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
| Line 97: | Line 149: | ||
* http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html | * http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html | ||
| − | * http://www. | + | * http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html |
* http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity | * http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity | ||
* http://jn.physiology.org/content/107/10/2633 | * http://jn.physiology.org/content/107/10/2633 | ||
* http://www.impulsecontroldisorders.org/html/cravings.html | * http://www.impulsecontroldisorders.org/html/cravings.html | ||
Latest revision as of 18:26, 28 April 2019
Nucleus Accumbens Core
@@Home -> BiologicalLifeResearch -> BrainAreaFEC -> BrainRegionFEC_FT_ACC_CORE
This page covers biological details of component Nucleus Accumbens Core. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Core (FEC.FT.ACC.CORE) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Motor Motivational Salience (FECLM)
- Role: basal.ganglia.striatum
- Function: cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | excitatory-glu | uncertain | (unknown reference) |
| FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | excitatory-glu | uncertain | Amygdala and its network (BLN -> NACC, abstract) | |
| FMM | FMM.FD.TH.RH | Rhomboidal Nucleus of Thalamus | excitatory-glu | uncertain | (unknown reference) |
| FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | uncertain | Nucleus Accumbens (CA1 -> NACC, abstract) | |
| FMM.FT.HF.SUBD | Distal Subiculum | excitatory-glu | uncertain | Nucleus Accumbens (SUB -> NACC, abstract) | |
| FMM.FT.HF.SUBP | Proximal Subiculum | excitatory-glu | uncertain | Nucleus Accumbens (SUB -> NACC, abstract) | |
| FMM.NC.PH.LEC | Lateral Entorhinal Cortex | excitatory-glu | uncertain | Nucleus Accumbens (EC -> NACC, abstract) | |
| FMM.NC.PH.PAS | Parasubiculum | excitatory-glu | uncertain | Nucleus Accumbens (PAS -> NACC, abstract) | |
| FMM.NC.PH.PER | Perirhinal Cortex | excitatory-glu | uncertain | Nucleus Accumbens (PRR -> NACC, abstract) | |
| NDM | NDM.FD.TH.PV | Paraventricular Nucleus of Thalamus | excitatory-glu | uncertain | (unknown reference) |
| NDM.NC.AL.FPC | Lateral Frontopolar Cortex | excitatory-glu | uncertain | Affective basal ganglia circuit (OMPFC -> NACC, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.FD.LHB.LT | Lateral Habenula Lateral Part | inhibitory-gaba | uncertain | Connectivity map of the habenula (NAc -> L, abstract) |
| FEC | FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | inhibitory-gaba | uncertain | (unknown reference) |
| FEC.FT.SNR.MED | Substantia Nigra Pars Reticulata Medial | inhibitory-gaba | uncertain | Craving (NACC -> SNr, abstract) | |
| FEC.FT.VP.DL | Ventral Pallidum Dorsolateral | inhibitory-gaba | uncertain | Craving (NACC -> VPAL, abstract) | |
| LMC | LMC.MM.VTA | Ventral Tegmental Area | inhibitory-gaba | uncertain | Reward circuit of human brain (NACC -> VTA, abstract) |
Thirdparty Circuits
(generated)
- Saccadic Vision - see Reference (CP.SACCADIC-VISION)
BG=Basal Ganglia,FEC.FT.BG CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FrontalCortex=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) Thalamus=Thalamus,FD.TH VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Bowels control brain: gut hormones and obesity - see Reference (CP.BOWELS)
AMY=Amygdala,FAM.FT.AM ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia) LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ME=Endocrine Glands,TARGET.TEA.ENDOCRINE NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) NTS=Solitary Nucleus,LPC.HL.SOL OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM VTA=Ventral Tegmental Area,LMC.MM.VTA
- Reward circuit of human brain - see Reference (CF.REWARD-CIRCUIT)
AM=Amygdala,FAM.FT.AM HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
References
(generated)
- http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
- http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity
- http://jn.physiology.org/content/107/10/2633
- http://www.impulsecontroldisorders.org/html/cravings.html
