Difference between revisions of "BrainRegionLMC MM RP DRN"
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<pre style="color: green">Dorsal Raphe Nucleus</pre> | <pre style="color: green">Dorsal Raphe Nucleus</pre> | ||
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_MM_RP_DRN]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_MM_RP_DRN]] | ||
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* '''Top-down path to region''': Midbrain Mesencephalon -> [[BrainCenterMM_RF|Mesencephalic Reticular Formation]] (MM.RF) -> Mesencephalic Reticular Formation, Midline Column (MM.RF.MID) -> [[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus]] (LMC.MM.RP.DRN) (see [[OverallMindMaps|Mind Maps]]) | * '''Top-down path to region''': Midbrain Mesencephalon -> [[BrainCenterMM_RF|Mesencephalic Reticular Formation]] (MM.RF) -> Mesencephalic Reticular Formation, Midline Column (MM.RF.MID) -> [[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus]] (LMC.MM.RP.DRN) (see [[OverallMindMaps|Mind Maps]]) | ||
* '''Type''': nucleus | * '''Type''': nucleus | ||
− | * '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]] | + | * '''Quality''': L0 |
− | * '''Role''': | + | * '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]] (LMC) |
+ | * '''Area circuit''': Serotonin - Feelings of Well-Being and Happiness (5HT) | ||
+ | * '''Role''': processor.autonomic | ||
* '''Function''': Regulation of sleep and mood | * '''Function''': Regulation of sleep and mood | ||
− | * '''Notes to function''': Major source of 5HT | + | * '''Notes to function''': |
+ | ** Major source of 5HT | ||
+ | ** inhibitory nucleus | ||
(generated) | (generated) | ||
= Components = | = Components = | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN)] |
|- | |- | ||
− | | [[BrainAreaFEC|FEC]] || [[ | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> DRN)] |
|- | |- | ||
− | | || [[ | + | | || [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> DRN)] |
|- | |- | ||
− | | [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_FD_TH_SF|LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || inhibitory-gaba || (unknown reference) | + | | [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_FD_TH_SF|LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || inhibitory-gaba || uncertain ||(unknown reference) |
|- | |- | ||
− | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HP_RP_LI|LMC.HP.RP.LI]] || Raphe Nucleus Linearis || modulatory-5ht || (unknown reference) | + | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HP_RP_LI|LMC.HP.RP.LI]] || Raphe Nucleus Linearis || modulatory-5ht || uncertain ||(unknown reference) |
|} | |} | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[ | + | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_FD_TH_PV|NDM.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || modulatory-5ht || uncertain || (unknown reference) |
|} | |} | ||
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(generated) | (generated) | ||
− | * [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] | + | * [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] (CF.HB-DA5HT) |
− | <img src="http:// | + | DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]] |
+ | DRN=[[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus,LMC.MM.RP.DRN]] | ||
+ | GPb=Dorsal Pallidum,FEC.FT.DP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
+ | LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | LHbL=[[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part,FAM.FD.LHB.LT]] | ||
+ | LHbM=[[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part,FAM.FD.LHB.MED]] | ||
+ | LPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]] | ||
+ | LS=[[BrainRegionFAM_FT_SEP_LT|Lateral Septal Nucleus,FAM.FT.SEP.LT]] | ||
+ | MHb=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
+ | MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]]) | ||
+ | MS=[[BrainRegionFAM_FT_SEP_MED|Medial Septal Nucleus,FAM.FT.SEP.MED]] | ||
+ | PS=Posterior Septal Group,FAM.FT.SEP.PG (see [[BrainCenterFAM_FT_SEP|Septal Nuclei]]) | ||
+ | RMTg=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]] | ||
+ | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | VP=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/97cf0802ee48a418ff7f70f80ce204e1.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference] | + | * [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference] (CF.HB-CONNECTIONS) |
− | <img src="http:// | + | CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
+ | DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]] | ||
+ | DR=[[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus,LMC.MM.RP.DRN]] | ||
+ | GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | IP=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
+ | LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see [[BrainCenterFD_HT|Hypothalamus]]) | ||
+ | LHb=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]]) | ||
+ | LPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]] | ||
+ | MHb=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
+ | MR=[[BrainRegionLMC_MM_RP_SUC|Superior Central Raphe Nucleus,LMC.MM.RP.SUC]] | ||
+ | PB=[[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands,TARGET.TEA.ENDOCRINE]] | ||
+ | S=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]] | ||
+ | SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]] | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/fa0c61d9adf99556d6de6701a35123b8.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
Latest revision as of 18:29, 28 April 2019
Dorsal Raphe Nucleus
@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_MM_RP_DRN
This page covers biological details of component Dorsal Raphe Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) -> Mesencephalic Reticular Formation, Midline Column (MM.RF.MID) -> Dorsal Raphe Nucleus (LMC.MM.RP.DRN) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Modulatory Contol Area (LMC)
- Area circuit: Serotonin - Feelings of Well-Being and Happiness (5HT)
- Role: processor.autonomic
- Function: Regulation of sleep and mood
- Notes to function:
- Major source of 5HT
- inhibitory nucleus
(generated)
Components
(generated)
Component items:
- Serotonergic cell group B7
Connectivity
(generated)
Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Role | Reference |
FAM | FAM.FD.LHB.MED | Lateral Habenula Medial Part | excitatory-glu | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN) |
FEC | FEC.HT.TG.IPD | Interpeduncular Nucleus | modulatory-ach | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> DRN) |
FEC.HT.TG.RMTG | Rostromedial Tegmental Nucleus | inhibitory-gaba | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> DRN) | |
LLC | LLC.FD.TH.SF | Subfascicular Nucleus of Thalamus | inhibitory-gaba | uncertain | (unknown reference) |
LMC | LMC.HP.RP.LI | Raphe Nucleus Linearis | modulatory-5ht | uncertain | (unknown reference) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Role | Reference |
NDM | NDM.FD.TH.PV | Paraventricular Nucleus of Thalamus | modulatory-5ht | uncertain | (unknown reference) |
Thirdparty Circuits
(generated)
- Both LHb and MHb control the dopaminergic and serotonergic systems - see Reference (CF.HB-DA5HT)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO LS=Lateral Septal Nucleus,FAM.FT.SEP.LT MHb=Medial Habenula,FAM.FD.MHB MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) MS=Medial Septal Nucleus,FAM.FT.SEP.MED PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei) RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Habenula Connections - see Reference (CF.HB-CONNECTIONS)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) IP=Interpeduncular Nucleus,FEC.HT.TG.IPD LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO MHb=Medial Habenula,FAM.FD.MHB MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC PB=Endocrine Glands,TARGET.TEA.ENDOCRINE S=Septal Nuclei,FAM.FT.SEP SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT VTA=Ventral Tegmental Area,LMC.MM.VTA
References
(generated)