Difference between revisions of "BrainRegionLAC FD HT VLPO"

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* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference]
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* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference] (CL.TBM-PO)
  
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map:
 
 
  LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 
  LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 
  LDTg=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]]
 
  LDTg=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]]
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* [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference]
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* [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] (CF.HB-DA5HT)
  
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  DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]]
 
  DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]]
 
  DRN=[[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus,LMC.MM.RP.DRN]]
 
  DRN=[[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus,LMC.MM.RP.DRN]]
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* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference]
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* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference] (CF.HB-CONNECTIONS)
  
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  CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 
  CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 
  DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]]
 
  DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]]
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* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference]
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* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES)
  
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  ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 
  ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 
  DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 
  DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]

Revision as of 03:19, 29 November 2018

Ventrolateral Preoptic Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLAC -> BrainRegionLAC_FD_HT_VLPO

This page covers biological details of component Ventrolateral Preoptic Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> Ventrolateral Preoptic Nucleus (LAC.FD.HT.VLPO) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Autonomous Control Area
  • Role: processor.autonomic
  • Function: mediates non-REM sleep onset
  • Notes to function: lesions in VLPO result in insomnia

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Components

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  • no child items defined

Connectivity

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LAC.FD.HT.VLPO.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.AM.MEA Medial Anterior Amygdaloid Nucleus excitatory-glu Role for serotonin in moral behavior (AMY -> HYP, abstract)
FAM.FT.SEP.LT Lateral Septal Nucleus inhibitory-gaba Cingulate Gyrus (SEP -> HT, abstract)
FEC FEC.HT.TG.RMTG Rostromedial Tegmental Nucleus inhibitory-gaba (unknown reference)
LAC LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus excitatory-glu Eating and sleeping to survive (DMH -> VLPO)
LAC.FD.HT.SCN Suprachiasmatic Nucleus excitatory-glu (unknown reference)
LAC.FD.HT.TBM Tuberomammillary Nucleus excitatory-glu Simplified NREM sleep-promoting pathway (TMN -> VLPO)
LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus excitatory-glu (unknown reference)
LMC LMC.HT.LC Locus Coeruleus modulatory-ne Simplified NREM sleep-promoting pathway (LC -> VLPO)
NSA NSA.NC.PH.PRP Prepyriform Cortex excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FD.LHB.LT Lateral Habenula Lateral Part excitatory-glu Habenula Connections (LPO -> LHb, abstract)
FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LPO -> LHbM)
LAC LAC.FD.HT.SUM Supramammillary Nucleus excitatory-glu (unknown reference)
LMC LMC.HT.TG.LDT Laterodorsal Tegmental Nucleus excitatory-glu Simplified NREM sleep-promoting pathway (VLPO -> LDTg)

Thirdparty Circuits

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LC=Locus Coeruleus,LMC.HT.LC
LDTg=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
TMN=Tuberomammillary Nucleus,LAC.FD.HT.TBM
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO


DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT
LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
LS=Lateral Septal Nucleus,FAM.FT.SEP.LT
MHb=Medial Habenula,FAM.FD.MHB
MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
MS=Medial Septal Nucleus,FAM.FT.SEP.MED
PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei)
RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
IP=Interpeduncular Nucleus,FEC.HT.TG.IPD
LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
LHb=Lateral Habenula,FAM.FD.LHB (see Habenula)
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
MHb=Medial Habenula,FAM.FD.MHB
MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC
PB=Endocrine Glands,TARGET.TEA.ENDOCRINE
S=Septal Nuclei,FAM.FT.SEP
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
VTA=Ventral Tegmental Area,LMC.MM.VTA


ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM


References

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