BrainRegionFEC FT ACC SH

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Nucleus Accumbens Shell

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This page covers biological details of component Nucleus Accumbens Shell. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Shell (FEC.FT.ACC.SH) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Forebrain - Execution Control Area
  • Role: basal.ganglia.striatum
  • Function: cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects

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Components

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  • no child items defined

Connectivity

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FEC.FT.ACC.SH.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FEC FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral modulatory-da Connectivity map of the habenula (SNc -> CPu, abstract)
FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial modulatory-da Connectivity map of the habenula (SNc -> CPu, abstract)
LAC LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus excitatory-glu Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)
LMC LMC.MM.VTA Ventral Tegmental Area modulatory-da Craving (VTA -> NACC, abstract)
LPC LPC.HL.SOL Solitary Nucleus excitatory-glu Bowels control brain: gut hormones and obesity (NTS -> NAc, abstract)
LPC.HT.PRF.PB Parabrachial Nucleus excitatory-glu Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)
NCP NCP.NC.MPL.PSCG Posterior Cingulate Cortex excitatory-glu (unknown reference)
NDM NDM.NC.AL.VACG Ventral Anterior Cingulate Area excitatory-glu Global visual system (FrontalCortex -> BGA, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FD.MHB Medial Habenula inhibitory-gaba Connectivity map of the habenula (NAc -> M, abstract)
FEC FEC.FT.IPAC.LT Lateral Interstitial Anterior Commissural Nucleus inhibitory-gaba (unknown reference)
FEC.FT.VP.VM Ventral Pallidum Ventromedial inhibitory-gaba Craving (NACC -> VPAL, abstract)
LAC LAC.FD.HT.LTN Lateral Hypothalamic Nucleus inhibitory-gaba (unknown reference)
LMC LMC.FT.NBM Basal Nucleus of Meynert inhibitory-gaba Affective basal ganglia circuit (NACC -> nBM, abstract)

Thirdparty Circuits

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AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
EP=Endopiriform Nucleus,FAM.FT.EPF
Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
L=Lateral Habenula,FAM.FD.LHB (see Habenula)
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
M=Medial Habenula,FAM.FD.MHB
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
Septum=Septal Nuclei,FAM.FT.SEP
VTA=Ventral Tegmental Area,LMC.MM.VTA


NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
nBM=Basal Nucleus of Meynert,LMC.FT.NBM


References

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