BrainRegionNMA NC SMC F3

Supplementary Motor Area

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This page covers biological details of component Supplementary Motor Area. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Supplementary Motor Cortex (NMA.NC.SMC) -> Supplementary Motor Area (NMA.NC.SMC.F3) (see Mind Maps)
• Type: cortex
• Brain area: Neocortical Brain - Motor Aggregation Area
• Brodmann ID: 06
• Role: cortex.generic
• Function: Movement execution; Numerical and verbal mental-operation tasks
• Notes to function: from TH/VLo from from putamen; F1/F2/F4/24d - strong; F6/F7/F5/24c - modest; no input from the prefrontal lobe

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NMA	NMA.FD.TH.VA	Ventral Anterior Nucleus	excitatory-glu	Thalamocortical relationships (VA -> pVA, abstract)
	NMA.NC.PMC.F4	Ventral Caudal Premotor Cortex	feedforward-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.PU.MED	Dorsal Putamen Medial	excitatory-glu	Global visual system (FrontalCortex -> BGA, abstract)
LLC	LLC.HT.PRF.RTMG	Pontine Reticulotegmental Nucleus	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
LRC	LRC.HL.PRF.GCR	Gigantocellular Reticular Nucleus	excitatory-glu	Motor neurons control (CTX -> MRF, abstract)
	LRC.HT.PRF.CRF	Caudal Pontine Reticular Nucleus	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
NMA	NMA.NC.PMC.F2	Dorsal Caudal Premotor Cortex	feedforward-glu	3 Visual Cortex Paths (pre-SMA -> dPM, abstract)
	NMA.NC.PMC.F5	Ventral Rostral Premotor Cortex	feedforward-glu	3 Visual Cortex Paths (pre-SMA -> vPM, abstract)

Thirdparty Circuits

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• Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)

ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
BGA=Basal Ganglia,FEC.FT.BG
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OPN=Oculomotor Nucleus,LPC.MM.OCN
ParietalCortex=Parietal Lobe,NC.LOBE.PAR
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
VisualCortex=Occipital Lobe,NC.LOBE.OCC

• 3 Visual Cortex Paths - see Reference (CP.BASE-VISUAL-CORTEX-FLOWS)

IPL=Inferior Parietal Lobule,NC.IPL
IPS=Intraparietal Sulcus,NSA.NC.IPS
IT=Inferotemporal Area,NSA.NC.IT
LPC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
MI=Motor Cortex,NMA.NC.MC
OCC=Occipital Lobe,NC.LOBE.OCC
SPL=Superior Parietal Lobule,NC.SPL
dPM=Dorsal Premotor Cortex,MCA.NC.DPMC (see Premotor Cortex)
pre-SMA=Supplementary Motor Cortex,NMA.NC.SMC
vPM=Ventral Premotor Cortex,MCA.NC.VPMC (see Premotor Cortex)

• Motor neurons control - see Reference (CM.CR-MN)

CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
CTX=Anterior Lobe,NC.LOBE.ANT
EAMN=Anterior/Ventral Horn,SC.VH
EGMN=Anterior/Ventral Horn,SC.VH
FAMN=Anterior/Ventral Horn,SC.VH
FG=Fastigual Nucleus,LRC.HT.CR.FG
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
MRF=Medullary Reticular Formation,HL.RF
PRF=Pontine Reticular Formation,HT.RF
RD=Red Nucleus,LLC.MM.RD
VB=Vestibular Nuclei,LPC.HT.VBN

References

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• http://www.sciencedirect.com/science/article/pii/S0959438808001566
• article:Biological/2008-dorsal-stream.pdf
• http://openagrosrl.com/www/page/292/