BrainCenterFD HT

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Hypothalamus

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This page covers biological details of component group Hypothalamus. Component group is part of aHuman target integrated biological model.

  • Top-down path to center: Forebrain Diencephalon -> Hypothalamus (FD.HT) (see Mind Maps)
  • Function:

(generated)

Components

(generated)


Component items:

Connectivity

(generated)


Internal Regions Connections:

unavailable


Source Region Target Region Reference
Anterior Hypothalamic Nucleus (LAC.FD.HT.AH) Dorsomedial Hypothalamic Nucleus (LAC.FD.HT.DM) Intrahypothalamic connections important for neural control of food intake and energy balance (AH -> DMN)
Premammillary Nucleus (LAC.FD.HT.PRM) (unknown reference)
Ventromedial Hypothalamic Nucleus (LAC.FD.HT.VM) Intrahypothalamic connections important for neural control of food intake and energy balance (AH -> VMN)
Arcuate Nucleus of Hypothalamus (LAC.FD.HT.AR) Dorsomedial Hypothalamic Nucleus (LAC.FD.HT.DM) Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> DMN)
Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN) Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)
Paraventricular Nucleus (LAC.FD.HT.PV) Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> PA)
Ventromedial Hypothalamic Nucleus (LAC.FD.HT.VM) Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH)
Dorsomedial Hypothalamic Nucleus (LAC.FD.HT.DM) Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN) Eating and sleeping to survive (DMH -> LHA)
Preoptic Nucleus (LAC.FD.HT.PO) Eating and sleeping to survive (DMH -> VLPO)
Paraventricular Nucleus (LAC.FD.HT.PV) Eating and sleeping to survive (DMH -> PVH)
Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN) Paraventricular Nucleus (LAC.FD.HT.PV) Schematic of hypothalamic circuitry underlying satiety (LHA -> PVN)
Preoptic Nucleus (LAC.FD.HT.PO) Anterior Hypothalamic Nucleus (LAC.FD.HT.AH) Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> AH)
Paraventricular Nucleus (LAC.FD.HT.PV) Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA)
Supraoptic Nucleus (LAC.FD.HT.SO) Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> SON)
Supramammillary Nucleus (LAC.FD.HT.SUM) (unknown reference)
Premammillary Nucleus (LAC.FD.HT.PRM) Preoptic Nucleus (LAC.FD.HT.PO) (unknown reference)
Ventromedial Hypothalamic Nucleus (LAC.FD.HT.VM) (unknown reference)
Suprachiasmatic Nucleus (LAC.FD.HT.SCN) Dorsomedial Hypothalamic Nucleus (LAC.FD.HT.DM) Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> DMN)
Preoptic Nucleus (LAC.FD.HT.PO) Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)
Paraventricular Nucleus (LAC.FD.HT.PV) Food-entrainable circadian oscillator (SCN -> PVH)
Supramammillary Nucleus (LAC.FD.HT.SUM) Lateral Mammillary Nucleus (FMM.FD.MB.LMB) Mammillary bodies: two memory systems in one (SupraMM -> LMB)
Tuberomammillary Nucleus (LAC.FD.HT.TBM) Medial Mammillary Nucleus (FMM.FD.MB.MMB) Mammillary bodies: two memory systems in one (TuberoMM -> MMB, abstract)
Preoptic Nucleus (LAC.FD.HT.PO) Simplified NREM sleep-promoting pathway (TMN -> VLPO)
Ventromedial Hypothalamic Nucleus (LAC.FD.HT.VM) Dorsomedial Hypothalamic Nucleus (LAC.FD.HT.DM) Intrahypothalamic connections important for neural control of food intake and energy balance (VMN -> DMN)
Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN) Glucose-sensing neural network (VMH -> LHA)
Preoptic Nucleus (LAC.FD.HT.PO) (unknown reference)
Paraventricular Nucleus (LAC.FD.HT.PV) Glucose-sensing neural network (VMH -> PVH)

External Connections:

unavailable

External Inbound Center Connections:

Source Center Sample Link Reference
Amygdala (FAM.FT.AM) FAM.FT.AM.BP -> LAC.FD.HT.DM Role for serotonin in moral behavior (AMY -> HYP, abstract)
Septal Nuclei (FAM.FT.SEP) FAM.FT.SEP.MED -> FMM.FD.MB.LMB Cingulate Gyrus (SEP -> HT, abstract)
Cognitive Thalamus (FD.TH.CR) LPC.FD.TH.PV -> LAC.FD.HT.PO (unknown reference)
Basal Ganglia (FEC.FT.BG) FEC.FT.ACC.SH -> LAC.FD.HT.LTN (unknown reference)
Hippocampal Formation (FMM.FT.HF) FMM.FT.HF.SUBP -> FMM.FD.MB.MMB Principal Connections of Hippocampus (HC -> MB, abstract)
Retrosubicular Area (FMM.NC.PHA.RS) FMM.NC.PH.POS -> FMM.FD.MB.LMB Head Direction Cell Circuit (PSUB -> LMB)
Myelencephalic Motor Nuclei (HL.MN) LRC.HL.INM -> LAC.FD.HT.PN (unknown reference)
Myelencephalic Sensory Nuclei (HL.SN) LPC.HL.SOL -> LAC.FD.HT.AR (unknown reference)
Pontine Reticular Formation (HT.RF) LPC.HT.PRF.PB -> LAC.FD.HT.DM Food-entrainable circadian oscillator (PBN -> DMH)
Pontine Tegmental Nuclei (HT.TG) LMC.HT.TG.DTG -> FMM.FD.MB.LMB (unknown reference)
Locus Coeruleus (LMC.HT.LC) LMC.HT.LC -> LAC.FD.HT.PO Simplified NREM sleep-promoting pathway (LC -> VLPO)
Ventral Tegmental Area (LMC.MM.VTA) LMC.MM.VTA -> FMM.FD.MB.MMB Mammillary bodies: two memory systems in one (VTN -> MMB)
Retina (LPC.FD.RT) LPC.FD.RT -> LAC.FD.HT.SCN Effect of light on pupil diameter (RET -> SCN)
Mesencephalic Reticular Formation (MM.RF) LMC.MM.RF.SUC -> FMM.FD.MB.MMB (unknown reference)
Anterior Cingulate Area (NC.ACG) NCP.NC.AL.SGCG -> LAC.FD.HT.AH (unknown reference)
Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) NDM.NC.AL.FPC -> LAC.FD.HT.RCH Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract)
Rhinal Cortex (NC.PHA.RH) FMM.NC.PH.MEC -> FMM.FD.MB.MMB Mammillary bodies: two memory systems in one (MedialEC -> MMB, abstract)

External Outbound Center Connections:

Target Center Sample Link Reference
Central canal (AVA.SC.CC) LAC.FD.HT.PV -> LAC.SC.CC.DCN (unknown reference)
Lateral Horn/Funiculus (BMA.SC.LH) LAC.FD.HT.PV -> LAC.SC.LH.LSN (unknown reference)
Habenula (FAM.FD.HB) LAC.FD.HT.LTN -> FAM.FD.LHB.LT Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)
Central Extended Amygdala (FAM.FT.CEAM) LAC.FD.HT.VM -> FAM.FT.BNST (unknown reference)
Septal Nuclei (FAM.FT.SEP) LAC.FD.HT.PN -> FAM.FT.SEP.LT (unknown reference)
Cognitive Thalamus (FD.TH.CR) FMM.FD.MB.LMB -> FMM.FD.TH.AD Head Direction Cell Circuit (LMB -> AD)
Subthalamus Area (FEC.FD.STA) LAC.FD.HT.VM -> FEC.FD.STN.CD (unknown reference)
Basal Ganglia (FEC.FT.BG) LAC.FD.HT.VM -> FEC.FT.ACC.SH Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)
Hippocampal Formation (FMM.FT.HF) LAC.FD.HT.PN -> FMM.FT.HC.CA3P (unknown reference)
Olfactory Nuclei (FT.OLF) LAC.FD.HT.TBM -> LPC.FT.MOB (unknown reference)
Medullary Reticular Formation (HL.RF) LAC.FD.HT.LTN -> LMC.HL.RP.MG (unknown reference)
Myelencephalic Sensory Nuclei (HL.SN) LAC.FD.HT.VM -> LPC.HL.SOL Bowels control brain: gut hormones and obesity (VMN -> NTS)
Pontine Reticular Formation (HT.RF) FMM.FD.MB.LMB -> LLC.HT.PRF.PDT Mammillary Body (LMB -> RTG)
Metencephalic Sensory Nuclei (HT.SN) FMM.FD.MB.MMB -> LLC.HT.PN.RSP Prefrontal Cortex (PFC) in emotional behavior (HT -> PN, abstract)
Pontine Tegmental Nuclei (HT.TG) FMM.FD.MB.LMB -> LMC.HT.TG.LDT Hippocampal Formation (LMam -> DTN)
Locus Coeruleus (LMC.HT.LC) LAC.FD.HT.DM -> LMC.HT.LC Effect of light on pupil diameter (DMH -> LC)
Periaqueductal Gray Matter (LMC.MM.PAG) LAC.FD.HT.VM -> LMC.MM.PAG Spine induction on short primary dendrites in the ventrolateral VMH (VMH -> PAG)
Reflexes Nuclei of Midbrain Mesencephalon (MM.REF) LAC.FD.HT.SCN -> LRC.MM.PT.NOT (unknown reference)
Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) LAC.FD.HT.LTN -> NDM.NC.AL.ROFCS Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract)
Intermediate Zone (SC.IZ) LAC.FD.HT.PN -> LAC.SC.IZ.CSC Sympathetic and parasympathetic eye pathways (PHT -> CC)
Anterior/Ventral Horn (SC.VH) LAC.FD.HT.PV -> LPC.SC.VH.ONF (unknown reference)
Endocrine Glands (TARGET.TEA.ENDOCRINE) LAC.FD.HT.AR -> TARGET.TEA.ENDOCRINE (unknown reference)