BrainRegionFAM FD LHB MED
Lateral Habenula Medial Part
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This page covers biological details of component Lateral Habenula Medial Part. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Habenula (FAM.FD.HB) -> Lateral Habenula (FAM.FD.LHB) -> Lateral Habenula Medial Part (FAM.FD.LHB.MED) (see Mind Maps)
- Type: nucleus
- Brain area: Forebrain - Affective Motivations Area
- Role: processor.affective.avoidance
- Function: Encoding negative feedback, direct, Septal
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FD.MHB | Medial Habenula | excitatory-glu | Connectivity map of the habenula (M -> L, abstract) |
| FAM.FT.SEP.DBB | Diagonal Band of Broca | inhibitory-gaba | Both LHb and MHb control the dopaminergic and serotonergic systems (DBB -> LHbM) | |
| FAM.FT.SEP.LT | Lateral Septal Nucleus | inhibitory-gaba | Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM) | |
| FEC | FEC.FT.VP.VM | Ventral Pallidum Ventromedial | inhibitory-gaba | Both LHb and MHb control the dopaminergic and serotonergic systems (VP -> LHbM, abstract) |
| LAC | LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | excitatory-glu | Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM) |
| LAC.FD.HT.VLPO | Ventrolateral Preoptic Nucleus | excitatory-glu | Both LHb and MHb control the dopaminergic and serotonergic systems (LPO -> LHbM) | |
| LMC | LMC.HT.LC | Locus Coeruleus | modulatory-ne | Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract) |
Outbound Region Connections:
Thirdparty Circuits
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map: DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB, DTG=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG, EPN=Endopiriform Nucleus,FAM.FT.EPF, GPi=Globus Pallidus Internal,FEC.FT.GPI (Globus Pallidus Internal Lateral (FEC.FT.GPI.LT), Globus Pallidus Internal Medial (FEC.FT.GPI.MED), Globus Pallidus Internal Dorsal (FEC.FT.GPI.DS), Globus Pallidus Internal Rostromedial (FEC.FT.GPI.RM), Globus Pallidus Internal Dorsolateral (FEC.FT.GPI.DL)), LHT=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT, LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED, NI=Incertus Nucleus,FAM.HT.TG.NI, RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG, Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (Raphe Pallidus Nucleus (LMC.HL.RP.PL), Raphe Obscurus Nucleus (LMC.HL.RP.OB), Raphe Magnus Nucleus (LMC.HL.RP.MG)), SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT), Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED)), VTA=Ventral Tegmental Area,LMC.MM.VTA, VTG=Ventral Tegmental Area,LMC.MM.VTG
map: DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB, DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN, GPb=Dorsal Pallidum,FEC.FT.DP (Globus Pallidus External Lateral (FEC.FT.GPE.LT), Globus Pallidus External Medial (FEC.FT.GPE.MED), Globus Pallidus External Dorsal (FEC.FT.GPE.DS), Globus Pallidus External Rostromedial (FEC.FT.GPE.RM), Globus Pallidus External Dorsolateral (FEC.FT.GPE.DL), Globus Pallidus Internal Lateral (FEC.FT.GPI.LT), Globus Pallidus Internal Medial (FEC.FT.GPI.MED), Globus Pallidus Internal Dorsal (FEC.FT.GPI.DS), Globus Pallidus Internal Rostromedial (FEC.FT.GPI.RM), Globus Pallidus Internal Dorsolateral (FEC.FT.GPI.DL)), IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT, LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED, LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO, LS=Lateral Septal Nucleus,FAM.FT.SEP.LT, MHb=Medial Habenula,FAM.FD.MHB, MRN=Raphe Nuclei of Medulla,LMC.HL.RP (Raphe Pallidus Nucleus (LMC.HL.RP.PL), Raphe Obscurus Nucleus (LMC.HL.RP.OB), Raphe Magnus Nucleus (LMC.HL.RP.MG)), MS=Medial Septal Nucleus,FAM.FT.SEP.MED, PS=Posterior Septal Group,FAM.FT.SEP.PG (Bed Nucleus of Anterior Commissure (FAM.FT.SEP.BAC), Septofimbrial Nucleus (FAM.FT.SEP.SF), Triangular Septal Nucleus (FAM.FT.SEP.TR)), RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG, SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT), Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED)), VP=Ventral Pallidum,FEC.FT.VP (Ventral Pallidum Dorsolateral (FEC.FT.VP.DL), Ventral Pallidum Ventromedial (FEC.FT.VP.VM)), VTA=Ventral Tegmental Area,LMC.MM.VTA
map: CPu=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB, DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN, GPi=Globus Pallidus Internal,FEC.FT.GPI (Globus Pallidus Internal Lateral (FEC.FT.GPI.LT), Globus Pallidus Internal Medial (FEC.FT.GPI.MED), Globus Pallidus Internal Dorsal (FEC.FT.GPI.DS), Globus Pallidus Internal Rostromedial (FEC.FT.GPI.RM), Globus Pallidus Internal Dorsolateral (FEC.FT.GPI.DL)), IP=Interpeduncular Nucleus,FEC.HT.TG.IPD, LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN), Supramammillary Nucleus (LAC.FD.HT.SUM), Tuberomammillary Nucleus (LAC.FD.HT.TBM), Premammillary Nucleus (LAC.FD.HT.PRM)), LHb=Lateral Habenula,FAM.FD.LHB (Lateral Habenula Medial Part (FAM.FD.LHB.MED), Lateral Habenula Lateral Part (FAM.FD.LHB.LT)), LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO, MHb=Medial Habenula,FAM.FD.MHB, MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC, PB=Endocrine Glands,TARGET.TEA.ENDOCRINE, S=Septal Nuclei,FAM.FT.SEP, SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT, VTA=Ventral Tegmental Area,LMC.MM.VTA
References
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