Difference between revisions of "BrainRegionFEC FT ACC CORE"
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_TH_PT|FAM.FD.TH.PT]] || Paratenial Nucleus of Thalamus || excitatory-glu || (unknown reference) | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_TH_PT|FAM.FD.TH.PT]] || Paratenial Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> NACC, abstract)] | + | | || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || uncertain ||[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> NACC, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_TH_RH|FMM.FD.TH.RH]] || Rhomboidal Nucleus of Thalamus || excitatory-glu || (unknown reference) | + | | [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_TH_RH|FMM.FD.TH.RH]] || Rhomboidal Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionFMM_FT_HC_CA1D|FMM.FT.HC.CA1D]] || Distal CA1 of Hippocampus || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (CA1 -> NACC, abstract)] | + | | || [[BrainRegionFMM_FT_HC_CA1D|FMM.FT.HC.CA1D]] || Distal CA1 of Hippocampus || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (CA1 -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_FT_HF_SUBD|FMM.FT.HF.SUBD]] || Distal Subiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)] | + | | || [[BrainRegionFMM_FT_HF_SUBD|FMM.FT.HF.SUBD]] || Distal Subiculum || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_FT_HF_SUBP|FMM.FT.HF.SUBP]] || Proximal Subiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)] | + | | || [[BrainRegionFMM_FT_HF_SUBP|FMM.FT.HF.SUBP]] || Proximal Subiculum || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (SUB -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (EC -> NACC, abstract)] | + | | || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (EC -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_NC_PH_PAS|FMM.NC.PH.PAS]] || Parasubiculum || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (PAS -> NACC, abstract)] | + | | || [[BrainRegionFMM_NC_PH_PAS|FMM.NC.PH.PAS]] || Parasubiculum || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (PAS -> NACC, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFMM_NC_PH_PER|FMM.NC.PH.PER]] || Perirhinal Cortex || excitatory-glu || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (PRR -> NACC, abstract)] | + | | || [[BrainRegionFMM_NC_PH_PER|FMM.NC.PH.PER]] || Perirhinal Cortex || excitatory-glu || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/nucleus-accumbens.jpg Nucleus Accumbens (PRR -> NACC, abstract)] |
|- | |- | ||
| − | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_FD_TH_PV|NDM.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || excitatory-glu || (unknown reference) | + | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_FD_TH_PV|NDM.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionNDM_NC_AL_FPC|NDM.NC.AL.FPC]] || Lateral Frontopolar Cortex || excitatory-glu || [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (OMPFC -> NACC, abstract)] | + | | || [[BrainRegionNDM_NC_AL_FPC|NDM.NC.AL.FPC]] || Lateral Frontopolar Cortex || excitatory-glu || uncertain ||[http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (OMPFC -> NACC, abstract)] |
|} | |} | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || inhibitory-gaba || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> L, abstract)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || inhibitory-gaba || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> L, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || inhibitory-gaba || (unknown reference) | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || inhibitory-gaba || uncertain || (unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_SNR_MED|FEC.FT.SNR.MED]] || Substantia Nigra Pars Reticulata Medial || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> SNr, abstract)] | + | | || [[BrainRegionFEC_FT_SNR_MED|FEC.FT.SNR.MED]] || Substantia Nigra Pars Reticulata Medial || inhibitory-gaba || uncertain || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> SNr, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_VP_DL|FEC.FT.VP.DL]] || Ventral Pallidum Dorsolateral || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)] | + | | || [[BrainRegionFEC_FT_VP_DL|FEC.FT.VP.DL]] || Ventral Pallidum Dorsolateral || inhibitory-gaba || uncertain || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || inhibitory-gaba || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (NACC -> VTA, abstract)] | + | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || inhibitory-gaba || uncertain || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (NACC -> VTA, abstract)] |
|} | |} | ||
Latest revision as of 18:26, 28 April 2019
Nucleus Accumbens Core
@@Home -> BiologicalLifeResearch -> BrainAreaFEC -> BrainRegionFEC_FT_ACC_CORE
This page covers biological details of component Nucleus Accumbens Core. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Core (FEC.FT.ACC.CORE) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Motor Motivational Salience (FECLM)
- Role: basal.ganglia.striatum
- Function: cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | excitatory-glu | uncertain | (unknown reference) |
| FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | excitatory-glu | uncertain | Amygdala and its network (BLN -> NACC, abstract) | |
| FMM | FMM.FD.TH.RH | Rhomboidal Nucleus of Thalamus | excitatory-glu | uncertain | (unknown reference) |
| FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | uncertain | Nucleus Accumbens (CA1 -> NACC, abstract) | |
| FMM.FT.HF.SUBD | Distal Subiculum | excitatory-glu | uncertain | Nucleus Accumbens (SUB -> NACC, abstract) | |
| FMM.FT.HF.SUBP | Proximal Subiculum | excitatory-glu | uncertain | Nucleus Accumbens (SUB -> NACC, abstract) | |
| FMM.NC.PH.LEC | Lateral Entorhinal Cortex | excitatory-glu | uncertain | Nucleus Accumbens (EC -> NACC, abstract) | |
| FMM.NC.PH.PAS | Parasubiculum | excitatory-glu | uncertain | Nucleus Accumbens (PAS -> NACC, abstract) | |
| FMM.NC.PH.PER | Perirhinal Cortex | excitatory-glu | uncertain | Nucleus Accumbens (PRR -> NACC, abstract) | |
| NDM | NDM.FD.TH.PV | Paraventricular Nucleus of Thalamus | excitatory-glu | uncertain | (unknown reference) |
| NDM.NC.AL.FPC | Lateral Frontopolar Cortex | excitatory-glu | uncertain | Affective basal ganglia circuit (OMPFC -> NACC, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.FD.LHB.LT | Lateral Habenula Lateral Part | inhibitory-gaba | uncertain | Connectivity map of the habenula (NAc -> L, abstract) |
| FEC | FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | inhibitory-gaba | uncertain | (unknown reference) |
| FEC.FT.SNR.MED | Substantia Nigra Pars Reticulata Medial | inhibitory-gaba | uncertain | Craving (NACC -> SNr, abstract) | |
| FEC.FT.VP.DL | Ventral Pallidum Dorsolateral | inhibitory-gaba | uncertain | Craving (NACC -> VPAL, abstract) | |
| LMC | LMC.MM.VTA | Ventral Tegmental Area | inhibitory-gaba | uncertain | Reward circuit of human brain (NACC -> VTA, abstract) |
Thirdparty Circuits
(generated)
- Saccadic Vision - see Reference (CP.SACCADIC-VISION)
BG=Basal Ganglia,FEC.FT.BG CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FrontalCortex=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) Thalamus=Thalamus,FD.TH VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Bowels control brain: gut hormones and obesity - see Reference (CP.BOWELS)
AMY=Amygdala,FAM.FT.AM ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia) LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ME=Endocrine Glands,TARGET.TEA.ENDOCRINE NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) NTS=Solitary Nucleus,LPC.HL.SOL OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM VTA=Ventral Tegmental Area,LMC.MM.VTA
- Reward circuit of human brain - see Reference (CF.REWARD-CIRCUIT)
AM=Amygdala,FAM.FT.AM HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
References
(generated)
- http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
- http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity
- http://jn.physiology.org/content/107/10/2633
- http://www.impulsecontroldisorders.org/html/cravings.html
