Difference between revisions of "BrainRegionFEC FT ACC SH"

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<pre style="color: green">Nucleus Accumbens Shell</pre>
 
<pre style="color: green">Nucleus Accumbens Shell</pre>
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_ACC_SH]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_ACC_SH]]
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Region is part of aHuman target integrated biological model.
 
Region is part of aHuman target integrated biological model.
  
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* '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterBGA_FT_BG|Basal Ganglia]] (BGA.FT.BG) -> Striatum (BGA.FT.ST) -> Ventral Striatum (BGA.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Shell (FEC.FT.ACC.SH) (see [[OverallMindMaps|Mind Maps]])
+
* '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> [[BrainRegionFEC_FT_ACC_SH|Nucleus Accumbens Shell]] (FEC.FT.ACC.SH) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': nucleus
 
* '''Type''': nucleus
−
* '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]]
+
* '''Quality''': L0
−
* '''Role''': relay
+
* '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] (FEC)
 +
* '''Area circuit''': Cognitive Motivational Salience (FECAF)
 +
* '''Role''': basal.ganglia.striatum
 
* '''Function''': cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects
 
* '''Function''': cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects
 
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
−
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
−
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || modulatory-da || (unknown reference)
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_LT|FEC.FT.SNC.LT]] || Substantia Nigra Pars Compacta Lateral || modulatory-da || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)]
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || modulatory-da || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (VTA -> NACC, abstract)]
+
| || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || modulatory-da || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)]
 
|-
 
|-
−
| [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_MPL_PSCG|NCP.NC.MPL.PSCG]] || Posterior Cingulate Cortex || excitatory-glu || (unknown reference)
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)]
 
|-
 
|-
−
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_VACG|NDM.NC.AL.VACG]] || Ventral Anterior Cingulate Area || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)]
+
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || modulatory-da || uncertain ||[http://www.impulsecontroldisorders.org/html/cravings.html Craving (VTA -> NACC, abstract)]
 +
|-
 +
| [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (NTS -> NAc, abstract)]
 +
|-
 +
|  || [[BrainRegionLPC_HT_PRF_PB|LPC.HT.PRF.PB]] || Parabrachial Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)]
 +
|-
 +
| [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_MPL_PSCG|NCP.NC.MPL.PSCG]] || Posterior Cingulate Cortex || excitatory-glu || uncertain ||(unknown reference)
 +
|-
 +
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_VACG|NDM.NC.AL.VACG]] || Ventral Anterior Cingulate Area || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)]
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
−
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
+
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
−
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_IPAC_LT|FEC.FT.IPAC.LT]] || Lateral Interstitial Anterior Commissural Nucleus || inhibitory-gaba || (unknown reference)
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_MHB|FAM.FD.MHB]] || Medial Habenula || inhibitory-gaba || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> M, abstract)]
 
|-
 
|-
−
| || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)]
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_IPAC_LT|FEC.FT.IPAC.LT]] || Lateral Interstitial Anterior Commissural Nucleus || inhibitory-gaba || uncertain || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || inhibitory-gaba || (unknown reference)
+
| || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || inhibitory-gaba || uncertain || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)]
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || Basal Nucleus of Meynert || inhibitory-gaba || [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (NACC -> nBM, abstract)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || inhibitory-gaba || uncertain || (unknown reference)
 +
|-
 +
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || Basal Nucleus of Meynert || inhibitory-gaba || uncertain || [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (NACC -> nBM, abstract)]
 
|}
 
|}
  
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(generated)
 
(generated)
  
−
* no circuits defined
+
* [http://neurowiki2012.wikispaces.com/file/view/Reward_circuit.jpg/315908202/Reward_circuit.jpg Reward circuit of human brain] - see [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reference] (CF.REWARD-CIRCUIT)
 +
 
 +
AM=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
 +
HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 +
VPAL=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/284310755a3e65beb74826e15beade5d.jpg" alt=alt="unavailable" style="max-width: 100%;">
 +
 
 +
* [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN)
 +
 
 +
CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]]
 +
Hippo=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]]
 +
L=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]])
 +
LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 +
M=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]]
 +
NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]]
 +
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]])
 +
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
Septum=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]]
 +
VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt=alt="unavailable" style="max-width: 100%;">
 +
 
 +
* [http://www.impulsecontroldisorders.org/images/8-Urges9proof.jpg Craving] - see [http://www.impulsecontroldisorders.org/html/cravings.html Reference] (CF.CRAVING)
 +
 
 +
NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 +
SNr=[[BrainRegionFEC_FT_SNR_MED|Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED]]
 +
VPAL=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/03180da352394bdd7711e289118a3d96.jpg" alt=alt="unavailable" style="max-width: 100%;">
 +
 
 +
* [http://www.expertsmind.com/CMSImages/250_Affective%20basal%20ganglia%20circuit.png Affective basal ganglia circuit] - see [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Reference] (CF.AFFECTIVE-BG)
 +
 
 +
NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 +
nBM=[[BrainRegionLMC_FT_NBM|Basal Nucleus of Meynert,LMC.FT.NBM]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/2b159b54189545739ee84da16d6bf0df.png" alt=alt="unavailable" style="max-width: 100%;">
 +
 
  
 
= References =
 
= References =
 
(generated)
 
(generated)
  
−
* no references defined
+
* http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity
 +
* http://jn.physiology.org/content/107/10/2633
 +
* http://www.impulsecontroldisorders.org/html/cravings.html
 +
* http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx

Latest revision as of 18:26, 28 April 2019

Nucleus Accumbens Shell

@@Home -> BiologicalLifeResearch -> BrainAreaFEC -> BrainRegionFEC_FT_ACC_SH

This page covers biological details of component Nucleus Accumbens Shell. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Shell (FEC.FT.ACC.SH) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Forebrain - Execution Control Area (FEC)
  • Area circuit: Cognitive Motivational Salience (FECAF)
  • Role: basal.ganglia.striatum
  • Function: cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects

(generated)

Components

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  • no child items defined

Connectivity

(generated)


FEC.FT.ACC.SH.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FEC FEC.FT.SNC.LT Substantia Nigra Pars Compacta Lateral modulatory-da uncertain Connectivity map of the habenula (SNc -> CPu, abstract)
FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial modulatory-da uncertain Connectivity map of the habenula (SNc -> CPu, abstract)
LAC LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus excitatory-glu uncertain Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)
LMC LMC.MM.VTA Ventral Tegmental Area modulatory-da uncertain Craving (VTA -> NACC, abstract)
LPC LPC.HL.SOL Solitary Nucleus excitatory-glu uncertain Bowels control brain: gut hormones and obesity (NTS -> NAc, abstract)
LPC.HT.PRF.PB Parabrachial Nucleus excitatory-glu uncertain Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)
NCP NCP.NC.MPL.PSCG Posterior Cingulate Cortex excitatory-glu uncertain (unknown reference)
NDM NDM.NC.AL.VACG Ventral Anterior Cingulate Area excitatory-glu uncertain Global visual system (FrontalCortex -> BGA, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FAM FAM.FD.MHB Medial Habenula inhibitory-gaba uncertain Connectivity map of the habenula (NAc -> M, abstract)
FEC FEC.FT.IPAC.LT Lateral Interstitial Anterior Commissural Nucleus inhibitory-gaba uncertain (unknown reference)
FEC.FT.VP.VM Ventral Pallidum Ventromedial inhibitory-gaba uncertain Craving (NACC -> VPAL, abstract)
LAC LAC.FD.HT.LTN Lateral Hypothalamic Nucleus inhibitory-gaba uncertain (unknown reference)
LMC LMC.FT.NBM Basal Nucleus of Meynert inhibitory-gaba uncertain Affective basal ganglia circuit (NACC -> nBM, abstract)

Thirdparty Circuits

(generated) 

AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
EP=Endopiriform Nucleus,FAM.FT.EPF
Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
L=Lateral Habenula,FAM.FD.LHB (see Habenula)
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
M=Medial Habenula,FAM.FD.MHB
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
Septum=Septal Nuclei,FAM.FT.SEP
VTA=Ventral Tegmental Area,LMC.MM.VTA


NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
nBM=Basal Nucleus of Meynert,LMC.FT.NBM


References

(generated)

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