BrainRegionNCP NC PG S1
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Primary Somatosensory Cortex
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This page covers biological details of component Primary Somatosensory Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Parietal Lobe (NC.LOBE.PAR) -> Postcentral Gyrus (NC.PG) -> Anterior Parietal Cortex (NC.PG.APC) -> Primary Somatosensory Cortex (NCP.NC.PG.S1) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Neocortical Brain - Conscious Personality Area (NCP)
- Area circuit: Neocortical Somatic Aggregation (SOM)
- Brodmann ID: 01,02,03
- Role: cortex.sensory.primary
- Function: Muscle and skin receptors
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| NCP | NCP.FD.TH.VPL | Ventral Posterolateral Nucleus | excitatory-glu | Pain matrix (TH.VPL -> S1) |
| NCP.FD.TH.VPM | Ventral Posteromedial Nucleus | excitatory-glu | Pain matrix (TH.VPM -> S1) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FEC | FEC.FT.PU.LT | Dorsal Putamen Lateral | excitatory-glu | Basal Ganglia Activity (S1 -> PU, abstract) |
| LRC | LRC.HL.TGS.PA5 | Paratrigeminal Nucleus | excitatory-glu | (unknown reference) |
| NCP | NCP.NC.PG.PV | Parietal Ventral Cortex | feedforward-glu | (unknown reference) |
| NCP.NC.PG.S2 | Secondary Somatosensory Cortex | feedforward-glu | Afferent pain pathways (S1 -> S2) | |
| NCP.NC.SPL.SA | Somatosensory Association Cortex | feedforward-glu | Cortico-Cortical Connectivity (S1 -> SA) | |
| NMA | NMA.NC.MC | Motor Cortex | feedforward-glu | Cortico-Cortical Connectivity (S1 -> M1) |
| NMA.NC.PMC.F2 | Dorsal Caudal Premotor Cortex | feedforward-glu | Global visual system (ParietalCortex -> FrontalCortex, abstract) | |
| NMA.NC.PMC.F5 | Ventral Rostral Premotor Cortex | feedforward-glu | Primate Control of Grasping (S2 -> F5) | |
| NPE | NPE.FD.TH.OPV | Oral Pulvinar | excitatory-glu | (unknown reference) |
| NPE.NC.IPL.SMW | Supramarginal Wernike Cortex | feedforward-glu | Cortico-Cortical Connectivity (S1 -> PTHA, abstract) | |
| NPE.NC.SPL.PG | Caudal Precuneus | feedforward-glu | McNaughton Spatial Processing Network (SomSensCortex -> PosteriorParietalCortex) |
Thirdparty Circuits
(generated)
- McNaughton Spatial Processing Network - see Reference (CP.VISUAL-SPATIAL-PROCESSING)
EnthCortex=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HF=Hippocampal Formation,FMM.FT.HF ITCortex=Inferotemporal Area,NSA.NC.IT PCGRSP=Medial Parietal Lobule,NC.MPL ParInsVestCortex=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP PosteriorParietalCortex=Caudal Precuneus,NPE.NC.SPL.PG SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) SomSensCortex=Primary Somatosensory Cortex,NCP.NC.PG.S1 VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Primate Control of Grasping - see Reference (CM.GRASPING-CONTROL)
46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) AIP=Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP BG=Basal Ganglia,FEC.FT.BG BTH=Ventral Anterior Nucleus,NMA.FD.TH.VA F1=Motor Cortex,NMA.NC.MC F2=Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2 F4=Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4 F5=Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5 F6=Pre-Supplementary Motor Area,NMA.NC.SMC.F6 IT=Inferotemporal Area,NSA.NC.IT PIP=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 S2=Primary Somatosensory Cortex,NCP.NC.PG.S1 VC=Occipital Lobe,NC.LOBE.OCC VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP
- Basal Ganglia Activity - see Reference (CM.BASAL-GANGLIA-ACTIVITY)
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) GPo=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) M1=Motor Cortex,NMA.NC.MC PMC=Premotor Cortex,NC.PMC PU=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia) S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 SMC=Supplementary Motor Cortex,NMA.NC.SMC SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia) STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) VLo=Ventral Lateral Nucleus,NMA.FD.TH.VL
- Cortico-Cortical Connectivity - see Reference (CL.CORTICO-CORTICAL-CONNECTIVITY)
A1=Primary Auditory Cortex,NSA.NC.TTG.A1 AA=Wernicke's area A3,NSA.NC.STG.A3 M1=Motor Cortex,NMA.NC.MC MA=Premotor Cortex,NC.PMC PFC=Prefrontal Cortex,NC.AL.PFC PTHA=Inferior Parietal Lobule,NC.IPL S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 SA=Somatosensory Association Cortex,NCP.NC.SPL.SA V1=Primary Visual Cortex,NSA.NC.OCC.V1 VA=Secondary Visual Cortex,NSA.NC.OCC.V2 (see Occipital Lobe)
- Afferent pain pathways - see Reference (CF.PAIN-PATH)
ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AMY=Amygdala,FAM.FT.AM BG=Basal Ganglia,FEC.FT.BG Cerebellum=Cerebellar Complex,LLC.HT.CRC Insula=Insular Cortex,NC.INS PAG=Periaqueductal Gray Matter,LMC.MM.PAG PB=Parabrachial Nucleus,LPC.HT.PRF.PB PFC=Prefrontal Cortex,NC.AL.PFC S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2 SC=Posterior/Dorsal Horn,BMA.SC.PH Thalamus=Sensory Thalamus,FD.TH.SR
- Somatic Senses - see Reference (CM.SOMATIC-SENSES)
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
- Owl Monkey Somatic Area - see Reference (CM.OWL-MONKEY)
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
- Homunculus S1 and M1 - see Reference (CM.HOMUNCULUS)
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
- Thalamocortical relationships - see Reference (CL.THALAMUS-PROJECTIONS)
A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MGN=Medial Geniculate Body,NSA.FD.TH.MGB P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus) VA=Ventral Anterior Nucleus,NMA.FD.TH.VA VL=Ventral Lateral Nucleus,NMA.FD.TH.VL VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia) pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) pLGN=Primary Visual Cortex,NSA.NC.OCC.V1 pLP=Superior Parietal Lobule,NC.SPL pMD=Prefrontal Cortex,NC.AL.PFC pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1 pP=Insular Cortex,NC.INS pVA=Supplementary Motor Cortex,NMA.NC.SMC pVL=Motor Cortex,NMA.NC.MC pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1 pVPM=Precentral Cortex,NCP.NC.PO.PCC s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) s1MD=Septal Nuclei,FAM.FT.SEP s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV s1VL=Dentate Nucleus,LLC.HT.CR.DN s2A=Mammillary Body,FD.MB (see Hypothalamus) s2MD=Piriform Cortex,NSA.NC.PH.PIR s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR s2VL=Basal Ganglia,FEC.FT.BG s3MD=Prefrontal Cortex,NC.AL.PFC sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) sLD=Superior Parietal Lobule,NC.SPL sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) sVA=Basal Ganglia,FEC.FT.BG sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn) sVPM=Solitary Nucleus,LPC.HL.SOL
- Pain matrix - see Reference (CF.SOMATOSENSORY-THALAMUS)
INS=Posterior Insular Cortex,NCP.NC.INS.PIC S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 TH.VPI=Ventral Posteroinferior Nucleus,NCP.FD.TH.VPI TH.VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL TH.VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
- Pain matrix - see Reference (CF.PAIN-MATRIX)
ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AM=Amygdala,FAM.FT.AM INS=Insular Cortex,NC.INS PAG=Periaqueductal Gray Matter,LMC.MM.PAG PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PPC=Superior Parietal Lobule,NC.SPL S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 SMA=Supplementary Motor Cortex,NMA.NC.SMC TH=Thalamus,FD.TH
References
(generated)
- http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html
- http://www.sciencedirect.com/science/article/pii/S0959438808001566
- http://www.sciencedirect.com/science/article/pii/S0893608098000471
- http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html
- http://www.sciencedirect.com/science/article/pii/S1053810011000080
- http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html
- http://www.biopsychology.com/6e/step0801.html
- http://www.scholarpedia.org/article/User:Tony_J._Prescott/Proposed/Primate_S1_cortex
- http://brainmind.com/BasalGanglia.html
- http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/
- http://users.atw.hu/blp6/BLP6/HTML/C0079780323045827.htm
- http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s10194-006-0307-1-0
