BrainRegionNCP NC INS AIC
Anterior Insular Cortex
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This page covers biological details of component Anterior Insular Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Insular Cortex (NC.INS) -> Anterior Insular Cortex (NCP.NC.INS.AIC) (see Mind Maps)
- Type: cortex
- Brain area: Neocortical Brain - Conscious Personality Area
- Brodmann ID: 14
- Role: cortex.generic
- Function: Risky and moral decision making, articulation
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FT.EPF | Endopiriform Nucleus | excitatory-glu | Gustatory sensory system of rat and macaque (EnP -> Iav, abstract) |
| NCP | NCP.FD.TH.MDC | Central Mediodorsal Nucleus of Thalamus | excitatory-glu | Amygdalar disruption of prefrontal cortex (TH -> INS, abstract) |
| NCP.NC.INS.PIC | Posterior Insular Cortex | feedforward-glu | Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract) | |
| NCP.NC.TPC | Temporopolar Cortex | feedforward-glu | Directed Effort Network (tPole -> Insula, abstract) | |
| NSA | NSA.NC.PH.PIR | Piriform Cortex | feedforward-glu | Gustatory sensory system of rat and macaque (PiR -> Iav, abstract) |
| NSA.NC.PH.PRP | Prepyriform Cortex | feedforward-glu | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FMM | FMM.NC.PH.PER | Perirhinal Cortex | feedforward-glu | Gustatory sensory system of rat and macaque (Iav -> PrC, abstract) |
| NDM | NDM.NC.AL.IPG | Inferior Prefrontal Gyrus | feedforward-glu | Directed Effort Network (Insula -> fPole, abstract) |
| NDM.NC.AL.VACG | Ventral Anterior Cingulate Area | feedforward-glu | Amygdalar disruption of prefrontal cortex (INS -> ACG, abstract) |
Thirdparty Circuits
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map: AC22=Wernicke's area A4,NSA.NC.STG.A4, ACA=Auditory Association Area,NSA.NC.TTG.A2, AM=Amygdala,FAM.FT.AM, DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), HC=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), Insula=Insular Cortex,NC.INS, OPFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PPC=Inferior Parietal Lobule,NC.IPL, dACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG, fPole=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG, tPole=Temporopolar Cortex,NCP.NC.TPC, vACC=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG
map: EnP=Endopiriform Nucleus,FAM.FT.EPF, Gud=Insular Cortex,NC.INS, Gug=Insular Cortex,NC.INS, HF=Hippocampal Formation,FMM.FT.HF, IadIap=Insular Cortex,NC.INS, Iav=Insular Cortex,NC.INS, NST=Solitary Nucleus,LPC.HL.SOL, PB=Parabrachial Nucleus,LPC.HT.PRF.PB, PiR=Piriform Cortex,NSA.NC.PH.PIR, PrC=Perirhinal Cortex,FMM.NC.PH.PER, VPMpc=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
map: ACG=Anterior Cingulate Cortex,NC.AL.ACG (Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG)), AM=Amygdala,FAM.FT.AM, HC=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN), Supramammillary Nucleus (LAC.FD.HT.SUM), Tuberomammillary Nucleus (LAC.FD.HT.TBM), Premammillary Nucleus (LAC.FD.HT.PRM)), HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV, INS=Insular Cortex,NC.INS, LC=Locus Coeruleus,LMC.HT.LC, MPFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PAG=Periaqueductal Gray Matter,LMC.MM.PAG, PB=Parabrachial Nucleus,LPC.HT.PRF.PB, PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE, SOL=Solitary Nucleus,LPC.HL.SOL, TH=Thalamus,FD.TH (Lateral Geniculate Nucleus (NSA.FD.LGN), Medial Geniculate Body (NSA.FD.TH.MGB), Ventral Posteroinferior Nucleus (NCP.FD.TH.VPI), Ventral Posterolateral Nucleus (NCP.FD.TH.VPL), Ventral Posteromedial Nucleus (NCP.FD.TH.VPM), Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV), Limitans Nucleus of Thalamus (NCP.FD.TH.LI), Suprageniculate Nucleus of Thalamus (NSA.FD.TH.SG), Submedial Nucleus of Thalamus (NDM.FD.TH.SM), Ventral Anterior Nucleus (NMA.FD.TH.VA), Ventral Lateral Nucleus (NMA.FD.TH.VL), Lateral Dorsal Nucleus of Thalamus (FMM.FD.TH.LD), Lateral Posterior Nucleus of Thalamus (NPE.FD.TH.LP), Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM), Central Mediodorsal Nucleus of Thalamus (NCP.FD.TH.MDC), Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL), Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD), Rostral Intralaminar Nuclear Group of Thalamus (NCP.FD.TH.RIL), Centromedian Nucleus of Thalamus (FEC.FD.TH.CM), Parafascicular Nucleus of Thalamus (FEC.FD.TH.PF), Paratenial Nucleus of Thalamus (FAM.FD.TH.PT), Paraventricular Nucleus of Thalamus (NDM.FD.TH.PV), Reuniens Nucleus of Thalamus (FMM.FD.TH.RE), Rhomboidal Nucleus of Thalamus (FMM.FD.TH.RH), Subfascicular Nucleus of Thalamus (LLC.FD.TH.SF))
References
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