Difference between revisions of "BrainRegionFEC FT SNC LT"
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* '''Type''': nucleus | * '''Type''': nucleus | ||
* '''Quality''': L0 | * '''Quality''': L0 | ||
| − | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] | + | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] (FEC) |
| + | * '''Area circuit''': Executive/Cognitive Loop (FECEXE) | ||
* '''Role''': basal.ganglia.nigracompacta | * '''Role''': basal.ganglia.nigracompacta | ||
* '''Function''': executive loop | * '''Function''': executive loop | ||
| Line 30: | Line 31: | ||
{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> SNc, abstract)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || uncertain ||[http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> SNc, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_CN_HD|FEC.FT.CN.HD]] || Caudate Nucleus Head || inhibitory-gaba || [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/saccades.jpg Saccades and smooth movements (CN -> SN, abstract)] | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_CN_HD|FEC.FT.CN.HD]] || Caudate Nucleus Head || inhibitory-gaba || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/saccades.jpg Saccades and smooth movements (CN -> SN, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_GPI_DS|FEC.FT.GPI.DS]] || Globus Pallidus Internal Dorsal || inhibitory-gaba || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] | + | | || [[BrainRegionFEC_FT_GPI_DS|FEC.FT.GPI.DS]] || Globus Pallidus Internal Dorsal || inhibitory-gaba || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_SNR_DL|FEC.FT.SNR.DL]] || Substantia Nigra Pars Reticulata Dorsolateral || inhibitory-gaba || [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Oculomotor decision-making (SNr -> SNc)] | + | | || [[BrainRegionFEC_FT_SNR_DL|FEC.FT.SNR.DL]] || Substantia Nigra Pars Reticulata Dorsolateral || inhibitory-gaba || uncertain ||[http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Oculomotor decision-making (SNr -> SNc)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_SNR_RM|FEC.FT.SNR.RM]] || Substantia Nigra Pars Reticulata Rostromedial || inhibitory-gaba || (unknown reference) | + | | || [[BrainRegionFEC_FT_SNR_RM|FEC.FT.SNR.RM]] || Substantia Nigra Pars Reticulata Rostromedial || inhibitory-gaba || uncertain ||(unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> SNc, abstract)] | + | | || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> SNc, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_SC_DEEP|LRC.MM.SC.DEEP]] || Deep Superior Colliculus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (SCi -> SNc, abstract)] | + | | [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_SC_DEEP|LRC.MM.SC.DEEP]] || Deep Superior Colliculus || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (SCi -> SNc, abstract)] |
|} | |} | ||
| Line 50: | Line 51: | ||
{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || modulatory-da || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || modulatory-da || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_PU_LT|FEC.FT.PU.LT]] || Dorsal Putamen Lateral || modulatory-da || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (SNC -> PU)] | + | | || [[BrainRegionFEC_FT_PU_LT|FEC.FT.PU.LT]] || Dorsal Putamen Lateral || modulatory-da || uncertain || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (SNC -> PU)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_PU_MED|FEC.FT.PU.MED]] || Dorsal Putamen Medial || modulatory-da || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] | + | | || [[BrainRegionFEC_FT_PU_MED|FEC.FT.PU.MED]] || Dorsal Putamen Medial || modulatory-da || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_HT_CR_CC|LLC.HT.CR.CC]] || Cerebellar Lateral Lobe || modulatory-da || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)] | + | | [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_HT_CR_CC|LLC.HT.CR.CC]] || Cerebellar Lateral Lobe || modulatory-da || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)] |
|- | |- | ||
| − | | || [[ | + | | || [[BrainRegionLLC_MM_RD_MG|LLC.MM.RD.MG]] || Magnocellular Part of Red Nucleus || modulatory-da || uncertain || (unknown reference) |
|} | |} | ||
Latest revision as of 18:26, 28 April 2019
Substantia Nigra Pars Compacta Lateral
@@Home -> BiologicalLifeResearch -> BrainAreaFEC -> BrainRegionFEC_FT_SNC_LT
This page covers biological details of component Substantia Nigra Pars Compacta Lateral. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Executive/Cognitive Loop (FECEXE)
- Role: basal.ganglia.nigracompacta
- Function: executive loop
- Notes to function:
- DP, dorsal circuits
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FD.LHB.MED | Lateral Habenula Medial Part | excitatory-glu | uncertain | Habenula Connections (LHb -> SNc, abstract) |
| FEC | FEC.FT.CN.HD | Caudate Nucleus Head | inhibitory-gaba | uncertain | Saccades and smooth movements (CN -> SN, abstract) |
| FEC.FT.GPI.DS | Globus Pallidus Internal Dorsal | inhibitory-gaba | uncertain | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
| FEC.FT.SNR.DL | Substantia Nigra Pars Reticulata Dorsolateral | inhibitory-gaba | uncertain | Oculomotor decision-making (SNr -> SNc) | |
| FEC.FT.SNR.RM | Substantia Nigra Pars Reticulata Rostromedial | inhibitory-gaba | uncertain | (unknown reference) | |
| FEC.HT.TG.IPD | Interpeduncular Nucleus | modulatory-ach | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> SNc, abstract) | |
| LRC | LRC.MM.SC.DEEP | Deep Superior Colliculus | excitatory-glu | uncertain | Global visual system (SCi -> SNc, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FEC | FEC.FT.ACC.SH | Nucleus Accumbens Shell | modulatory-da | uncertain | Connectivity map of the habenula (SNc -> CPu, abstract) |
| FEC.FT.PU.LT | Dorsal Putamen Lateral | modulatory-da | uncertain | Physiology and pathophysiology of lower urinary tract (SNC -> PU) | |
| FEC.FT.PU.MED | Dorsal Putamen Medial | modulatory-da | uncertain | Connectivity map of the habenula (SNc -> CPu, abstract) | |
| LLC | LLC.HT.CR.CC | Cerebellar Lateral Lobe | modulatory-da | uncertain | Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract) |
| LLC.MM.RD.MG | Magnocellular Part of Red Nucleus | modulatory-da | uncertain | (unknown reference) |
Thirdparty Circuits
(generated)
- Saccadic Vision - see Reference (CP.SACCADIC-VISION)
BG=Basal Ganglia,FEC.FT.BG CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FrontalCortex=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) Thalamus=Thalamus,FD.TH VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey - see Reference (CM.SN-PPN)
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia) STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
- Prefrontal Cortex (PFC) in motor behavior - see Reference (CM.PFC-MOTOR)
CN.PU=Striatum,FEC.FT.ST (see Basal Ganglia) CR=Cerebellar Complex,LLC.HT.CRC GP=Globus Pallidus,FEC.FT.GP (see Basal Ganglia) LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) MC=Motor Cortex,NMA.NC.MC PMC=Premotor Cortex,NC.PMC PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei) SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia) TH=Ventral Thalamus,FD.TH.VTH (see Motor Thalamus)
- Physiology and pathophysiology of lower urinary tract - see Reference (CM.ONUF)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) DVM=Vagus Nucleus,LAC.HL.VGN IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG IML=Intermediolateral Nucleus,LAC.SC.IZ.IML LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO NBM=Basal Nucleus of Meynert,LMC.FT.NBM ONF=Onuf's Nucleus,LPC.SC.VH.ONF PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG PU=Dorsal Putamen Lateral,FEC.FT.PU.LT PVN=Paraventricular Nucleus,LAC.FD.HT.PV SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS VTA=Ventral Tegmental Area,LMC.MM.VTA ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
- Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)
AMYG=Amygdala,FAM.FT.AM CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL Thalamus=Thalamus,FD.TH VTA=Ventral Tegmental Area,LMC.MM.VTA
- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Normal Functional Anatomy of Basal Ganglia - see Reference (CM.NORMAL-BG-ANATOMY)
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) VA=Ventral Anterior Nucleus,NMA.FD.TH.VA VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
- Habenula Connections - see Reference (CF.HB-CONNECTIONS)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) IP=Interpeduncular Nucleus,FEC.HT.TG.IPD LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO MHb=Medial Habenula,FAM.FD.MHB MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC PB=Endocrine Glands,TARGET.TEA.ENDOCRINE S=Septal Nuclei,FAM.FT.SEP SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT VTA=Ventral Tegmental Area,LMC.MM.VTA
References
(generated)
- http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html
- http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs
- https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
- http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
- http://jn.physiology.org/content/107/10/2633
- http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0
- http://www.sciencedirect.com/science/article/pii/S0959438808001566
- http://www.mdvu.org/library/disease/pd/par_path.asp
- http://www.scholarpedia.org/article/Habenula
