Difference between revisions of "BrainRegionFEC FT SNC LT"
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<pre style="color: green">Substantia Nigra Pars Compacta Lateral</pre> | <pre style="color: green">Substantia Nigra Pars Compacta Lateral</pre> | ||
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_SNC_LT]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_SNC_LT]] | ||
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Region is part of aHuman target integrated biological model. | Region is part of aHuman target integrated biological model. | ||
− | * '''Top-down path to region''': Forebrain Telencephalon -> [[ | + | * '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> [[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral]] (FEC.FT.SNC.LT) (see [[OverallMindMaps|Mind Maps]]) |
* '''Type''': nucleus | * '''Type''': nucleus | ||
− | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] | + | * '''Quality''': L0 |
− | * '''Role''': | + | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] (FEC) |
+ | * '''Area circuit''': Executive/Cognitive Loop (FECEXE) | ||
+ | * '''Role''': basal.ganglia.nigracompacta | ||
* '''Function''': executive loop | * '''Function''': executive loop | ||
− | * '''Notes to function''': DP, dorsal circuits | + | * '''Notes to function''': |
+ | ** DP, dorsal circuits | ||
(generated) | (generated) | ||
= Components = | = Components = | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> SNc, abstract)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || uncertain ||[http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> SNc, abstract)] |
|- | |- | ||
− | | | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_CN_HD|FEC.FT.CN.HD]] || Caudate Nucleus Head || inhibitory-gaba || uncertain ||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/saccades.jpg Saccades and smooth movements (CN -> SN, abstract)] |
|- | |- | ||
− | | | + | | || [[BrainRegionFEC_FT_GPI_DS|FEC.FT.GPI.DS]] || Globus Pallidus Internal Dorsal || inhibitory-gaba || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] |
|- | |- | ||
− | | || [[ | + | | || [[BrainRegionFEC_FT_SNR_DL|FEC.FT.SNR.DL]] || Substantia Nigra Pars Reticulata Dorsolateral || inhibitory-gaba || uncertain ||[http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Oculomotor decision-making (SNr -> SNc)] |
|- | |- | ||
− | | || [[ | + | | || [[BrainRegionFEC_FT_SNR_RM|FEC.FT.SNR.RM]] || Substantia Nigra Pars Reticulata Rostromedial || inhibitory-gaba || uncertain ||(unknown reference) |
|- | |- | ||
− | | || [[ | + | | || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> SNc, abstract)] |
|- | |- | ||
− | | [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_SC_DEEP|LRC.MM.SC.DEEP]] || Deep Superior Colliculus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (SCi -> SNc, abstract)] | + | | [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_SC_DEEP|LRC.MM.SC.DEEP]] || Deep Superior Colliculus || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (SCi -> SNc, abstract)] |
|} | |} | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || modulatory-da || [http:// | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || modulatory-da || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] |
|- | |- | ||
− | | || [[BrainRegionFEC_FT_PU_LT|FEC.FT.PU.LT]] || Dorsal Putamen Lateral || modulatory-da || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (SNC -> PU)] | + | | || [[BrainRegionFEC_FT_PU_LT|FEC.FT.PU.LT]] || Dorsal Putamen Lateral || modulatory-da || uncertain || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (SNC -> PU)] |
|- | |- | ||
− | | || [[BrainRegionFEC_FT_PU_MED|FEC.FT.PU.MED]] || Dorsal Putamen Medial || modulatory-da || [http:// | + | | || [[BrainRegionFEC_FT_PU_MED|FEC.FT.PU.MED]] || Dorsal Putamen Medial || modulatory-da || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] |
|- | |- | ||
− | | [[BrainAreaLLC|LLC]] || [[ | + | | [[BrainAreaLLC|LLC]] || [[BrainRegionLLC_HT_CR_CC|LLC.HT.CR.CC]] || Cerebellar Lateral Lobe || modulatory-da || uncertain || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)] |
|- | |- | ||
− | | || [[ | + | | || [[BrainRegionLLC_MM_RD_MG|LLC.MM.RD.MG]] || Magnocellular Part of Red Nucleus || modulatory-da || uncertain || (unknown reference) |
|} | |} | ||
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(generated) | (generated) | ||
− | * [http://www.nature.com/nrn/journal/v5/n3/images/nrn1345-i1.jpg Saccadic Vision] - see [http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Reference] | + | * [http://www.nature.com/nrn/journal/v5/n3/images/nrn1345-i1.jpg Saccadic Vision] - see [http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Reference] (CP.SACCADIC-VISION) |
− | <img src="http:// | + | BG=[[BrainCenterFEC_FT_BG|Basal Ganglia,FEC.FT.BG]] |
+ | CN=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | CR=Cerebellum,LLC.HT.CR (see [[BrainCenterLLC_HT_CRC|Cerebellar Complex]]) | ||
+ | FrontalCortex=Anterior Lobe,NC.LOBE.ANT | ||
+ | GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | LGN=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]] | ||
+ | LIP=[[BrainRegionNPE_NC_IPS_LIP|Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP]] | ||
+ | RF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]] | ||
+ | Retina=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]] | ||
+ | SCi=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SCs=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SNpr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]] | ||
+ | STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]]) | ||
+ | Thalamus=Thalamus,FD.TH | ||
+ | VisualCortex=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/e149203d6ac92f76e1ccabaef41666a6.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http:// | + | * [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference] (CM.SN-PPN) |
− | <img src="http:// | + | GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
+ | GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | PPN=[[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]] | ||
+ | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]]) | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/ae877872fea7af03677243fd8481c11d.png" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/motor_top.jpg Prefrontal Cortex (PFC) in motor behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] | + | * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/motor_top.jpg Prefrontal Cortex (PFC) in motor behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CM.PFC-MOTOR) |
− | <img src="http:// | + | CN.PU=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
+ | CR=[[BrainCenterLLC_HT_CRC|Cerebellar Complex,LLC.HT.CRC]] | ||
+ | GP=Globus Pallidus,FEC.FT.GP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]]) | ||
+ | MC=[[BrainRegionNMA_NC_MC|Motor Cortex,NMA.NC.MC]] | ||
+ | PMC=[[BrainCenterNC_PMC|Premotor Cortex,NC.PMC]] | ||
+ | PN=Pontine Nuclear Complex,HT.PN (see [[BrainCenterHT_SN|Metencephalic Sensory Nuclei]]) | ||
+ | SN=Substantia Nigra,FEC.FT.SN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | TH=Ventral Thalamus,FD.TH.VTH (see [[BrainCenterFD_TH_MR|Motor Thalamus]]) | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/474417556f95e6d518821367eef6716a.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference] | + | * [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference] (CM.ONUF) |
− | <img src="http:// | + | CN=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
+ | DVM=[[BrainRegionLAC_HL_VGN|Vagus Nucleus,LAC.HL.VGN]] | ||
+ | IMG=[[BrainRegionLAC_PN_SYM_IMG|Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG]] | ||
+ | IML=[[BrainRegionLAC_SC_IZ_IML|Intermediolateral Nucleus,LAC.SC.IZ.IML]] | ||
+ | LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]] | ||
+ | MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
+ | MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]] | ||
+ | NBM=[[BrainRegionLMC_FT_NBM|Basal Nucleus of Meynert,LMC.FT.NBM]] | ||
+ | ONF=[[BrainRegionLPC_SC_VH_ONF|Onuf's Nucleus,LPC.SC.VH.ONF]] | ||
+ | PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]] | ||
+ | PEL=[[BrainRegionLAC_PN_PSYM_PPG|Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG]] | ||
+ | PU=[[BrainRegionFEC_FT_PU_LT|Dorsal Putamen Lateral,FEC.FT.PU.LT]] | ||
+ | PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]] | ||
+ | SNC=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]] | ||
+ | SPS=[[BrainRegionLAC_SC_IZ_SPS|Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS]] | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | ZI=[[BrainRegionFEC_FD_STN_CD|Subthalamic Nucleus Caudal,BGA.FD.STN.ZI]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/b3238c9c6efdcfa004931bec8815fc0b.jpeg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http:// | + | * [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN) |
− | <img src="http:// | + | CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
+ | EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]] | ||
+ | Hippo=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
+ | L=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]]) | ||
+ | LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | M=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
+ | NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]] | ||
+ | Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]]) | ||
+ | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | Septum=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]] | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://img.springerimages.com/Images/Springer/PUB=Springer-Verlag-Berlin-Heidelberg/JOU=00359/VOL=2005.191/ISU=3/ART=2004_565/MediaObjects/WATER_s00359-004-0565-9fhc1.jpg Oculomotor decision-making] - see [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Reference] | + | * [http://img.springerimages.com/Images/Springer/PUB=Springer-Verlag-Berlin-Heidelberg/JOU=00359/VOL=2005.191/ISU=3/ART=2004_565/MediaObjects/WATER_s00359-004-0565-9fhc1.jpg Oculomotor decision-making] - see [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Reference] (CP.OCULOMOTOR-DECISION-MAKING) |
− | <img src="http:// | + | AMYG=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]] |
+ | CGa=Anterior Cingulate Cortex,NC.AL.ACG (see [[BrainCenterNC_ACG|Anterior Cingulate Area]]) | ||
+ | CGp=[[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]] | ||
+ | Caudate=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see [[BrainCenterNC_PMC|Premotor Cortex]]) | ||
+ | LIP=[[BrainRegionNPE_NC_IPS_LIP|Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP]] | ||
+ | NAC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
+ | PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]]) | ||
+ | SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SEF=[[BrainRegionNPE_NC_SMC_SEF|Supplementary Eye Field,NPE.NC.SMC.SEF]] | ||
+ | SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]] | ||
+ | SNr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]] | ||
+ | Thalamus=Thalamus,FD.TH | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/1d4f1e638e95cbcc831ce811b7c2518a.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http:// | + | * [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference] (CP.GLOBAL-VISUAL-SYSTEM) |
− | <img src="http:// | + | ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]]) |
+ | BGA=[[BrainCenterFEC_FT_BG|Basal Ganglia,FEC.FT.BG]] | ||
+ | FrontalCortex=Anterior Lobe,NC.LOBE.ANT | ||
+ | LGN=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]] | ||
+ | OPN=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]] | ||
+ | ParietalCortex=Parietal Lobe,NC.LOBE.PAR | ||
+ | Pulvinar=Pulvinar,FD.PV (see [[BrainCenterFD_TH_SR|Sensory Thalamus]]) | ||
+ | RF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]] | ||
+ | Retina=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]] | ||
+ | SCi=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SCs=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]] | ||
+ | SNr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]] | ||
+ | SpinalCord=Lamina IX,SC.VH.L9 (see [[BrainCenterSC_VH|Anterior/Ventral Horn]]) | ||
+ | Striatum=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | VisualCortex=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/7192d7e1c7041f25a6eddc32c4f67e91.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://www. | + | * [http://www.mdvu.org/images/par_path2.jpg Normal Functional Anatomy of Basal Ganglia] - see [http://www.mdvu.org/library/disease/pd/par_path.asp Reference] (CM.NORMAL-BG-ANATOMY) |
− | <img src="http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg" alt="unavailable"> | + | GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
+ | GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]] | ||
+ | SNr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]] | ||
+ | STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]]) | ||
+ | VA=[[BrainRegionNMA_FD_TH_VA|Ventral Anterior Nucleus,NMA.FD.TH.VA]] | ||
+ | VL=[[BrainRegionNMA_FD_TH_VL|Ventral Lateral Nucleus,NMA.FD.TH.VL]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/895abdcf81284500560c506cdd20f352.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference] (CF.HB-CONNECTIONS) | ||
+ | |||
+ | CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]] | ||
+ | DR=[[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus,LMC.MM.RP.DRN]] | ||
+ | GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | IP=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
+ | LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see [[BrainCenterFD_HT|Hypothalamus]]) | ||
+ | LHb=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]]) | ||
+ | LPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]] | ||
+ | MHb=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
+ | MR=[[BrainRegionLMC_MM_RP_SUC|Superior Central Raphe Nucleus,LMC.MM.RP.SUC]] | ||
+ | PB=[[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands,TARGET.TEA.ENDOCRINE]] | ||
+ | S=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]] | ||
+ | SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]] | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/fa0c61d9adf99556d6de6701a35123b8.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
Line 102: | Line 220: | ||
* http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html | * http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html | ||
− | * http://www. | + | * http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs |
* https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 | * https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 | ||
* http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders | * http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders | ||
− | * http:// | + | * http://jn.physiology.org/content/107/10/2633 |
* http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 | * http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 | ||
+ | * http://www.sciencedirect.com/science/article/pii/S0959438808001566 | ||
* http://www.mdvu.org/library/disease/pd/par_path.asp | * http://www.mdvu.org/library/disease/pd/par_path.asp | ||
* http://www.scholarpedia.org/article/Habenula | * http://www.scholarpedia.org/article/Habenula |
Latest revision as of 18:26, 28 April 2019
Substantia Nigra Pars Compacta Lateral
@@Home -> BiologicalLifeResearch -> BrainAreaFEC -> BrainRegionFEC_FT_SNC_LT
This page covers biological details of component Substantia Nigra Pars Compacta Lateral. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Executive/Cognitive Loop (FECEXE)
- Role: basal.ganglia.nigracompacta
- Function: executive loop
- Notes to function:
- DP, dorsal circuits
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Role | Reference |
FAM | FAM.FD.LHB.MED | Lateral Habenula Medial Part | excitatory-glu | uncertain | Habenula Connections (LHb -> SNc, abstract) |
FEC | FEC.FT.CN.HD | Caudate Nucleus Head | inhibitory-gaba | uncertain | Saccades and smooth movements (CN -> SN, abstract) |
FEC.FT.GPI.DS | Globus Pallidus Internal Dorsal | inhibitory-gaba | uncertain | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
FEC.FT.SNR.DL | Substantia Nigra Pars Reticulata Dorsolateral | inhibitory-gaba | uncertain | Oculomotor decision-making (SNr -> SNc) | |
FEC.FT.SNR.RM | Substantia Nigra Pars Reticulata Rostromedial | inhibitory-gaba | uncertain | (unknown reference) | |
FEC.HT.TG.IPD | Interpeduncular Nucleus | modulatory-ach | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> SNc, abstract) | |
LRC | LRC.MM.SC.DEEP | Deep Superior Colliculus | excitatory-glu | uncertain | Global visual system (SCi -> SNc, abstract) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Role | Reference |
FEC | FEC.FT.ACC.SH | Nucleus Accumbens Shell | modulatory-da | uncertain | Connectivity map of the habenula (SNc -> CPu, abstract) |
FEC.FT.PU.LT | Dorsal Putamen Lateral | modulatory-da | uncertain | Physiology and pathophysiology of lower urinary tract (SNC -> PU) | |
FEC.FT.PU.MED | Dorsal Putamen Medial | modulatory-da | uncertain | Connectivity map of the habenula (SNc -> CPu, abstract) | |
LLC | LLC.HT.CR.CC | Cerebellar Lateral Lobe | modulatory-da | uncertain | Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract) |
LLC.MM.RD.MG | Magnocellular Part of Red Nucleus | modulatory-da | uncertain | (unknown reference) |
Thirdparty Circuits
(generated)
- Saccadic Vision - see Reference (CP.SACCADIC-VISION)
BG=Basal Ganglia,FEC.FT.BG CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FrontalCortex=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) Thalamus=Thalamus,FD.TH VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey - see Reference (CM.SN-PPN)
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia) STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
- Prefrontal Cortex (PFC) in motor behavior - see Reference (CM.PFC-MOTOR)
CN.PU=Striatum,FEC.FT.ST (see Basal Ganglia) CR=Cerebellar Complex,LLC.HT.CRC GP=Globus Pallidus,FEC.FT.GP (see Basal Ganglia) LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) MC=Motor Cortex,NMA.NC.MC PMC=Premotor Cortex,NC.PMC PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei) SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia) TH=Ventral Thalamus,FD.TH.VTH (see Motor Thalamus)
- Physiology and pathophysiology of lower urinary tract - see Reference (CM.ONUF)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) DVM=Vagus Nucleus,LAC.HL.VGN IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG IML=Intermediolateral Nucleus,LAC.SC.IZ.IML LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO NBM=Basal Nucleus of Meynert,LMC.FT.NBM ONF=Onuf's Nucleus,LPC.SC.VH.ONF PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG PU=Dorsal Putamen Lateral,FEC.FT.PU.LT PVN=Paraventricular Nucleus,LAC.FD.HT.PV SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS VTA=Ventral Tegmental Area,LMC.MM.VTA ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
- Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)
AMYG=Amygdala,FAM.FT.AM CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL Thalamus=Thalamus,FD.TH VTA=Ventral Tegmental Area,LMC.MM.VTA
- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Normal Functional Anatomy of Basal Ganglia - see Reference (CM.NORMAL-BG-ANATOMY)
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) VA=Ventral Anterior Nucleus,NMA.FD.TH.VA VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
- Habenula Connections - see Reference (CF.HB-CONNECTIONS)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) IP=Interpeduncular Nucleus,FEC.HT.TG.IPD LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO MHb=Medial Habenula,FAM.FD.MHB MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC PB=Endocrine Glands,TARGET.TEA.ENDOCRINE S=Septal Nuclei,FAM.FT.SEP SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT VTA=Ventral Tegmental Area,LMC.MM.VTA
References
(generated)
- http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html
- http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs
- https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
- http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
- http://jn.physiology.org/content/107/10/2633
- http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0
- http://www.sciencedirect.com/science/article/pii/S0959438808001566
- http://www.mdvu.org/library/disease/pd/par_path.asp
- http://www.scholarpedia.org/article/Habenula