Revision as of 16:59, 27 November 2018

Oculomotor Nucleus

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This page covers biological details of component Oculomotor Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Midbrain Mesencephalon -> Perhipheral Nuclei of Midbrain Mesencephalon (MM.PER) -> Oculomotor Nucleus (LPC.MM.OCN) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Peripheral Control Area
• Role: flexor.nucleus
• Function: Change Eye Direction
• Notes to function: Muscle nucleus

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Components

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Component items:

• Anterior Median Oculomotor Nucleus
• Central Oculomotor Nucleus
• Caudal Central Oculomotor Nucleus
• Dorsal Oculomotor Nucleus
• Intermediate Oculomotor Nucleus
• Medial Oculomotor Nucleus
• Ventral Oculomotor Nucleus

Connectivity

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Inbound Region Connections:

Outbound Region Connections:

Thirdparty Circuits

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• Eye blink reflex and pupillary light reflex - see Reference

map: Abducens=Abducens Nucleus,LPC.HT.ABD, Ciliary=Ciliary Ganglion,LAC.PN.PSYM.CLG, EWN=Edinger-Westphal Nucleus,LAC.MM.EWN, EYE=Eye,TARGET.TSA.EYE, Facial=Facial Motor Nucleus,LPC.HT.FCM, Oculomotor=Oculomotor Nucleus,LPC.MM.OCN, Pretectum=Pretectum,MM.PT (Anterior Pretectum Nucleus (LRC.MM.PT.PTA), Nucleus of Optic Tract (LRC.MM.PT.NOT), Pretectal Olivary Nucleus (LRC.MM.PT.PON), Principal Pretectal Nucleus (LRC.MM.PT.PR), Sublentiform Nucleus (LRC.MM.PT.SL)), PrincipalTrigeminal=Principal Trigeminal Nucleus,LPC.HT.PN.PTR, RF=Pontine Reticular Formation,HT.RF, SpinalTrigeminal=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR, SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (Cajal Nucleus (LRC.MM.CJ), Rostral Interstitial Nucleus of MLF (LRC.MM.RIMLF), Darkschewitsch Nucleus (LRC.MM.DSCH)), VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (Dorsal Associative Visual Cortex (NPE.NC.OCC.V3D), Ventral Associative Visual Cortex (NPE.NC.OCC.V3V))

• Extraocular eye muscles - see Reference

map: ABD=Abducens Nucleus,LPC.HT.ABD, EYE=Eye,TARGET.TSA.EYE, OCN=Oculomotor Nucleus,LPC.MM.OCN, TRC=Trochlear Nucleus,LPC.MM.TRH

• Vision Components - see Reference

map: CG=Ciliary Ganglion,LAC.PN.PSYM.CLG, EWN=Edinger-Westphal Nucleus,LAC.MM.EWN, EYE=Eye,TARGET.TSA.EYE, LGN=Lateral Geniculate Nucleus,NSA.FD.LGN, OCN=Oculomotor Nucleus,LPC.MM.OCN, RT=Retinal Ganglion,LPC.PN.SG.RT, SOA=Supraoculomotor Area,VBA.MM.SOA (Cajal Nucleus (LRC.MM.CJ), Rostral Interstitial Nucleus of MLF (LRC.MM.RIMLF), Darkschewitsch Nucleus (LRC.MM.DSCH)), STN=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR, VAC=Posterior Eye Field,NPE.NC.IPS.PEF (Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP)), VC=Occipital Lobe,NC.LOBE.OCC

• Vestibulo-ocular reflex (VOR) - see Reference

map: Abducens=Abducens Nucleus,LPC.HT.ABD, FEF=Frontal Eye Field,NMA.NC.PMC.FEF (Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF)), Oculomotor=Oculomotor Nucleus,LPC.MM.OCN, PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (Oral Pontine Reticular Nucleus (LRC.HT.PRF.RPO), Caudal Pontine Reticular Nucleus (LRC.HT.PRF.CRF), Parvocellular Reticular Nucleus (LRC.HT.PRF.PVR)), VestibularGanglion=Vestibular Ganglion,LPC.PN.SG.VB, VestibularNuclei=Inferior Vestibular Nuclei,LPC.HT.IVBN

• Retina and superior colliculus targets - see Reference

map: Abducens=Abducens Nucleus,LPC.HT.ABD, LGB=Lateral Geniculate Nucleus,NSA.FD.LGN, OCC=Occipital Lobe,NC.LOBE.OCC, Oculomotor=Oculomotor Nucleus,LPC.MM.OCN, Pulvinar=Pulvinar,FD.PV (Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV)), Retina=Retinal Nucleus,LPC.FD.RT, SC=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), Trochlear=Trochlear Nucleus,LPC.MM.TRH

• Global visual system - see Reference

map: ATH=Anterior Nucleus of Thalamus,FD.TH.AN (Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD)), BGA=Basal Ganglia,FEC.FT.BG, FrontalCortex=Anterior Lobe,NC.LOBE.ANT (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC), Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG), Ventral Medial Cingulate Area (NDM.NC.AL.VMCG), Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG), Pregenual Cingulate Cortex (NDM.NC.AL.PGCG), Motor Cortex (NMA.NC.MC), Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF), Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7), Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5), Supplementary Eye Field (NPE.NC.SMC.SEF), Pre-Supplementary Motor Area (NMA.NC.SMC.F6), Supplementary Motor Area (NMA.NC.SMC.F3)), LGN=Lateral Geniculate Nucleus,NSA.FD.LGN, OPN=Oculomotor Nucleus,LPC.MM.OCN, ParietalCortex=Parietal Lobe,NC.LOBE.PAR (Medial Superior Temporal Area (NPE.NC.IPL.MST), Supramarginal Wernike Cortex (NPE.NC.IPL.SMW), Retrosplenial Cortex (NCP.NC.MPL.RSC), Posterior Cingulate Cortex (NCP.NC.MPL.PSCG), Subgenual Cingulate Cortex (NCP.NC.MPL.SGCG), Precentral Cortex (NCP.NC.PO.PCC), Primary Somatosensory Cortex (NCP.NC.PG.S1), Secondary Somatosensory Cortex (NCP.NC.PG.S2), Parietal Ventral Cortex (NCP.NC.PG.PV), Somatosensory Association Cortex (NCP.NC.SPL.SA), Rostral Precuneus (NPE.NC.SPL.PF), Caudal Precuneus (NPE.NC.SPL.PG), Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP), Ventral Intraparietal Sulcus (NSA.NC.IPS.VIP), Anterior Intraparietal Sulcus (NSA.NC.IPS.AIP)), Pulvinar=Pulvinar,FD.PV (Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV)), RF=Pontine Reticular Formation,HT.RF, Retina=Retinal Nucleus,LPC.FD.RT, SCi=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SCs=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT, SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL, SpinalCord=Lamina IX,SC.VH.L9 (Ventrolateral Nucleus (LPC.SC.VH.VL), Posterolateral Nucleus (LPC.SC.VH.PL), Retroposterolateral Nucleus (LPC.SC.VH.RPL), Spinal Accessory Nucleus (LPC.SC.VH.SAN), Phrenic Nucleus (LPC.SC.VH.PHR), Onuf's Nucleus (LPC.SC.VH.ONF)), Striatum=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), VisualCortex=Occipital Lobe,NC.LOBE.OCC

References

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• http://neuroscience.uth.tmc.edu/s3/chapter07.html
• http://what-when-how.com/neuroscience/the-cranial-nerves-organization-of-the-central-nervous-system-part-4
• http://www.neuroanatomy.wisc.edu/virtualbrain/BrainStem/13VNAN.html
• http://unifiedtao-en.blogspot.ru/2011/03/what-we-see-of-tao.html
• http://www.sciencedirect.com/science/article/pii/S0959438808001566