Revision as of 03:16, 29 November 2018

Substantia Nigra Pars Compacta Lateral

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This page covers biological details of component Substantia Nigra Pars Compacta Lateral. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Execution Control Area
Role: basal.ganglia.nigracompacta
Function: executive loop
Notes to function: DP, dorsal circuits

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Components

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no child items defined

Connectivity

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FEC.FT.SNC.LT.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FD.LHB.MED	Lateral Habenula Medial Part	excitatory-glu	Habenula Connections (LHb -> SNc, abstract)
FEC	FEC.FT.CN.HD	Caudate Nucleus Head	inhibitory-gaba	Saccades and smooth movements (CN -> SN, abstract)
	FEC.FT.GPI.DS	Globus Pallidus Internal Dorsal	inhibitory-gaba	Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)
	FEC.FT.SNR.DL	Substantia Nigra Pars Reticulata Dorsolateral	inhibitory-gaba	Oculomotor decision-making (SNr -> SNc)
	FEC.FT.SNR.RM	Substantia Nigra Pars Reticulata Rostromedial	inhibitory-gaba	(unknown reference)
	FEC.HT.TG.IPD	Interpeduncular Nucleus	modulatory-ach	Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> SNc, abstract)
LRC	LRC.MM.SC.DEEP	Deep Superior Colliculus	excitatory-glu	Global visual system (SCi -> SNc, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.ACC.SH	Nucleus Accumbens Shell	modulatory-da	Connectivity map of the habenula (SNc -> CPu, abstract)
	FEC.FT.PU.LT	Dorsal Putamen Lateral	modulatory-da	Physiology and pathophysiology of lower urinary tract (SNC -> PU)
	FEC.FT.PU.MED	Dorsal Putamen Medial	modulatory-da	Connectivity map of the habenula (SNc -> CPu, abstract)
LLC	LLC.HT.CR.CC	Cerebellar Lateral Lobe	modulatory-da	Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)
	LLC.MM.RD	Red Nucleus	modulatory-da	(unknown reference)

Thirdparty Circuits

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Saccadic Vision - see Reference (CP.SACCADIC-VISION)

BG=Basal Ganglia,FEC.FT.BG
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
Thalamus=Thalamus,FD.TH
VisualCortex=Occipital Lobe,NC.LOBE.OCC

Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey - see Reference (CM.SN-PPN)

GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia)
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)

Prefrontal Cortex (PFC) in motor behavior - see Reference (CM.PFC-MOTOR)

CN.PU=Striatum,FEC.FT.ST (see Basal Ganglia)
CR=Cerebellar Complex,LLC.HT.CRC
GP=Globus Pallidus,FEC.FT.GP (see Basal Ganglia)
LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
MC=Motor Cortex,NMA.NC.MC
PMC=Premotor Cortex,NC.PMC
PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei)
SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia)
TH=Ventral Thalamus,FD.TH.VTH (see Motor Thalamus)

Physiology and pathophysiology of lower urinary tract - see Reference (CM.ONUF)

CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
DVM=Vagus Nucleus,LAC.HL.VGN
IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG
IML=Intermediolateral Nucleus,LAC.SC.IZ.IML
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
NBM=Basal Nucleus of Meynert,LMC.FT.NBM
ONF=Onuf's Nucleus,LPC.SC.VH.ONF
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG
PU=Dorsal Putamen Lateral,FEC.FT.PU.LT
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS
VTA=Ventral Tegmental Area,LMC.MM.VTA
ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI

Connectivity map of the habenula - see Reference (CF.HB-CONN)

CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
EP=Endopiriform Nucleus,FAM.FT.EPF
Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
L=Lateral Habenula,FAM.FD.LHB (see Habenula)
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
M=Medial Habenula,FAM.FD.MHB
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
Septum=Septal Nuclei,FAM.FT.SEP
VTA=Ventral Tegmental Area,LMC.MM.VTA

Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)

AMYG=Amygdala,FAM.FT.AM
CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex)
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SEF=Supplementary Eye Field,NPE.NC.SMC.SEF
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
Thalamus=Thalamus,FD.TH
VTA=Ventral Tegmental Area,LMC.MM.VTA

Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)

ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
BGA=Basal Ganglia,FEC.FT.BG
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OPN=Oculomotor Nucleus,LPC.MM.OCN
ParietalCortex=Parietal Lobe,NC.LOBE.PAR
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
VisualCortex=Occipital Lobe,NC.LOBE.OCC

Normal Functional Anatomy of Basal Ganglia - see Reference (CM.NORMAL-BG-ANATOMY)

GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
VA=Ventral Anterior Nucleus,NMA.FD.TH.VA
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL

Habenula Connections - see Reference (CF.HB-CONNECTIONS)

CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
IP=Interpeduncular Nucleus,FEC.HT.TG.IPD
LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
LHb=Lateral Habenula,FAM.FD.LHB (see Habenula)
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
MHb=Medial Habenula,FAM.FD.MHB
MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC
PB=Endocrine Glands,TARGET.TEA.ENDOCRINE
S=Septal Nuclei,FAM.FT.SEP
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
VTA=Ventral Tegmental Area,LMC.MM.VTA

References

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@@ Line 64: / Line 64: @@
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-* [http://www.nature.com/nrn/journal/v5/n3/images/nrn1345-i1.jpg Saccadic Vision] - see [http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Reference]
+* [http://www.nature.com/nrn/journal/v5/n3/images/nrn1345-i1.jpg Saccadic Vision] - see [http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html Reference] (CP.SACCADIC-VISION)
- map:
   BG=[[BrainCenterFEC_FT_BG|Basal Ganglia,FEC.FT.BG]]
   CN=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
@@ Line 84: / Line 83: @@
 <img src="http://ahuman.org/svn/ahwiki/images/ext/e149203d6ac92f76e1ccabaef41666a6.jpg" alt=alt="unavailable" style="max-width: 100%;">
-* [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference]
+* [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference] (CM.SN-PPN)
- map:
   GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
   GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
@@ Line 95: / Line 93: @@
 <img src="http://ahuman.org/svn/ahwiki/images/ext/ae877872fea7af03677243fd8481c11d.png" alt=alt="unavailable" style="max-width: 100%;">
-* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/motor_top.jpg Prefrontal Cortex (PFC) in motor behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference]
+* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/motor_top.jpg Prefrontal Cortex (PFC) in motor behavior] - see [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Reference] (CM.PFC-MOTOR)
- map:
   CN.PU=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
   CR=[[BrainCenterLLC_HT_CRC|Cerebellar Complex,LLC.HT.CRC]]
@@ Line 109: / Line 106: @@
 <img src="http://ahuman.org/svn/ahwiki/images/ext/474417556f95e6d518821367eef6716a.jpg" alt=alt="unavailable" style="max-width: 100%;">
-* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference]
+* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference] (CM.ONUF)
- map:
   CN=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
   DVM=[[BrainRegionLAC_HL_VGN|Vagus Nucleus,LAC.HL.VGN]]
@@ Line 131: / Line 127: @@
 <img src="http://ahuman.org/svn/ahwiki/images/ext/b3238c9c6efdcfa004931bec8815fc0b.jpeg" alt=alt="unavailable" style="max-width: 100%;">
-* [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference]
+* [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN)
- map:
   CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
   EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]]
@@ Line 149: / Line 144: @@
 <img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt=alt="unavailable" style="max-width: 100%;">
-* [http://img.springerimages.com/Images/Springer/PUB=Springer-Verlag-Berlin-Heidelberg/JOU=00359/VOL=2005.191/ISU=3/ART=2004_565/MediaObjects/WATER_s00359-004-0565-9fhc1.jpg Oculomotor decision-making] - see [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Reference]
+* [http://img.springerimages.com/Images/Springer/PUB=Springer-Verlag-Berlin-Heidelberg/JOU=00359/VOL=2005.191/ISU=3/ART=2004_565/MediaObjects/WATER_s00359-004-0565-9fhc1.jpg Oculomotor decision-making] - see [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Reference] (CP.OCULOMOTOR-DECISION-MAKING)
- map:
   AMYG=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
   CGa=Anterior Cingulate Cortex,NC.AL.ACG (see [[BrainCenterNC_ACG|Anterior Cingulate Area]])
@@ Line 169: / Line 163: @@
 <img src="http://ahuman.org/svn/ahwiki/images/ext/1d4f1e638e95cbcc831ce811b7c2518a.jpg" alt=alt="unavailable" style="max-width: 100%;">
-* [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference]
+* [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference] (CP.GLOBAL-VISUAL-SYSTEM)
- map:
   ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
   BGA=[[BrainCenterFEC_FT_BG|Basal Ganglia,FEC.FT.BG]]
@@ Line 190: / Line 183: @@
 <img src="http://ahuman.org/svn/ahwiki/images/ext/7192d7e1c7041f25a6eddc32c4f67e91.jpg" alt=alt="unavailable" style="max-width: 100%;">
-* [http://www.mdvu.org/images/par_path2.jpg Normal Functional Anatomy of Basal Ganglia] - see [http://www.mdvu.org/library/disease/pd/par_path.asp Reference]
+* [http://www.mdvu.org/images/par_path2.jpg Normal Functional Anatomy of Basal Ganglia] - see [http://www.mdvu.org/library/disease/pd/par_path.asp Reference] (CM.NORMAL-BG-ANATOMY)
- map:
   GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
   GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
@@ Line 202: / Line 194: @@
 <img src="http://ahuman.org/svn/ahwiki/images/ext/895abdcf81284500560c506cdd20f352.jpg" alt=alt="unavailable" style="max-width: 100%;">
-* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference]
+* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference] (CF.HB-CONNECTIONS)
- map:
   CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
   DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]]

Difference between revisions of "BrainRegionFEC FT SNC LT"

Revision as of 03:16, 29 November 2018

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Connectivity

Thirdparty Circuits

References

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