BrainAreaLPC

Peripheral Control Area

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Local Circuits

(generated)

ID	Name	Regions
ABS	Breathing and Swallowing Motor	LPC.HL.AMB, LPC.SC.VH.PHR
AVB	Vestibular Sensory and Motor	LPC.HT.IVBN, LPC.HT.LVBN, LPC.HT.MVBN, LPC.HT.SVBN, LPC.PN.SG.CVB, LPC.PN.SG.SVB, LPC.PN.SG.UVB
AVM	Vision Motor	LPC.HT.ABD, LPC.MM.OCN, LPC.MM.TRH
AVS	Vision Sensory	LPC.FD.RT
MBE	Control Body Extensors	LPC.SC.VH.VL, LPC.SC.VH.VM
MBFG	Control Body Generic Flexors	LPC.SC.VH.PL, LPC.SC.VH.PM
MBFS	Control Body Special Flexors	LPC.SC.VH.ONF, LPC.SC.VH.RPL, LPC.SC.VH.SAN
MF	Control Face Muscles	LPC.HL.HYG, LPC.HT.FCM, LPC.HT.TRM
SA	Auditory Sense	LPC.HL.DCOCH, LPC.HL.VCOCH, LPC.HT.PN.LL, LPC.MM.CIC, LPC.MM.SOC, LPC.PN.SG.SP
SBC	Common Body Sensations	LPC.SC.LH.LCV, LPC.SC.PH.NP
SBL	Lower Body Conscious Sensations	LPC.HL.GR, LPC.PN.SG.LDRG, LPC.SC.PH.LMG, LPC.SC.PH.LSG
SBU	Upper Body Conscious Sensations	LPC.HL.CU, LPC.PN.SG.UDRG, LPC.SC.PH.UMG, LPC.SC.PH.USG
SF	Sensory Face	LPC.HL.TGS.STR, LPC.HT.PN.PTR, LPC.MM.MSTR, LPC.PN.SG.TRG
SP	Pain Sensations	LPC.FD.TH.PV, LPC.HT.PRF.PB
SSS	Smell Senses	LPC.FT.AOB, LPC.FT.AON, LPC.FT.MOB, LPC.PN.SG.MOE, LPC.PN.SG.VNO
STS	Taste Senses	LPC.HL.SOL, LPC.PN.SG.GNG, LPC.PN.SG.JUG, LPC.PN.SG.NOD, LPC.PN.SG.PET
SU	Unconscious Cerebellar Sensations	LPC.HL.ACU, LPC.SC.IZ.CBS, LPC.SC.IZ.IMM, LPC.SC.PH.CL

Breathing and Swallowing Motor

Component ID	Component Name	Type	Service	Function	Comments
LPC.HL.AMB	Ambiguus Nucleus	nucleus	LRM	Control muscles of the soft palate, pharynx, and larnyx	On par with VGM, speech; speech and swallowing
LPC.SC.VH.PHR	Phrenic Nucleus	nucleus	LMD	Innervation of diaphragm	Projections from Nucleus Solitarius

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NMA	LPC.HL.AMB	NMA.NC.MC	Motor Cortex	neocortex-nucleus	(unknown reference)
Subcortical
LMC	LPC.HL.AMB	LMC.MM.PAG	Periaqueductal Gray Matter	nucleus-nucleus-ENK	(unknown reference)
LPC	LPC.HL.AMB	LPC.HL.SOL	Solitary Nucleus	nucleus-nucleus	(unknown reference)
LRC	LPC.HL.AMB	LRC.HL.RA	Retroambigualis Nucleus	nucleus-nucleus	(unknown reference)
		LRC.HT.PRF.CRF	Caudal Pontine Reticular Nucleus	nucleus-nucleus	Vocal Control (RF -> NucleusAmbiguus, abstract)
	LPC.SC.VH.PHR	LRC.HL.RA	Retroambigualis Nucleus	nucleus-nucleus	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Target
TEA	LPC.HL.AMB	TARGET.TEA.FEEDER	Mouth feeder	inferior-pharyngeal-constrictor-muscle	(unknown reference)
		TARGET.TEA.LUNG	Lung	stylopharyngeus-muscle	(unknown reference)
		TARGET.TEA.SPEAKER	Mouth speaker	arytenoid-muscle	(unknown reference)
	LPC.SC.VH.PHR	TARGET.TEA.LUNG	Lung	thoracic-diaphragm	(unknown reference)
TSA	LPC.HL.AMB	TARGET.TSA.NOSE	Nose	nose-salpingopharyngeus	(unknown reference)

Vestibular Sensory and Motor

Component ID	Component Name	Type	Service	Function	Comments
LPC.HT.IVBN	Inferior Vestibular Nuclei	nucleus	LSM	maintain balance, coordinating postural adjustments	to CR; to oculomotor, trochlear, abducens, accessory oculomotor
LPC.HT.LVBN	Lateral Vestibular Nuclei	nucleus	LSM	controlling body position	to sacral, ipsilateral - lateral vestibulospinal tract
LPC.HT.MVBN	Medial Vestibular Nucleus	nucleus	LSM	controlling head position, integrate head and eye movements; maintain balance, coordinating postural adjustments; coordination for horizontal eye movements	to thoracic, bilateral - medial vestibulospinal tract in MLF; to CR; to oculomotor, trochlear, abducens, accessory oculomotor
LPC.HT.SVBN	Superior Vestibular Nuclei	nucleus	LSM	conscious perception of movement and gravity	to oculomotor, trochlear, abducens, accessory oculomotor; to VPI
LPC.PN.SG.CVB	Vestibular Ganglion - Semicircular Canal Neurons	sensory ganglion	LSC	Relay head movements in 3D coords
LPC.PN.SG.SVB	Vestibular Ganglion - Saccule Neurons	sensory ganglion	LSC	Relay vertical linear acceleration
LPC.PN.SG.UVB	Vestibular Ganglion - Utricle Neurons	sensory ganglion	LSC	Relay horizontal linear acceleration

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.PN.SG.CVB	LPC.HT.MVBN	ganglion-nucleus	(unknown reference)
	LPC.HT.SVBN	ganglion-nucleus	(unknown reference)
LPC.PN.SG.SVB	LPC.HT.IVBN	ganglion-nucleus	Vestibulo-ocular reflex (VOR) (VestibularGanglion -> VestibularNuclei, abstract)
	LPC.HT.LVBN	ganglion-nucleus	(unknown reference)
LPC.PN.SG.UVB	LPC.HT.LVBN	ganglion-nucleus	(unknown reference)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LLC	LPC.HT.IVBN	LLC.SC.IZ.CCV	Central Cervical Nucleus	nucleus-nucleus	(unknown reference)
	LPC.HT.LVBN	LLC.HT.CR.FN	Fastigual Nucleus	nucleus-nucleus	(unknown reference)
LRC	LPC.HT.IVBN	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	nucleus-nucleus	(unknown reference)
Target
TSA	LPC.PN.SG.CVB	TARGET.TSA.EAR	Ear	ear-semicircular-canals	(unknown reference)
	LPC.PN.SG.SVB	TARGET.TSA.EAR	Ear	ear-saccule	(unknown reference)
	LPC.PN.SG.UVB	TARGET.TSA.EAR	Ear	ear-utricle	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NSA	LPC.HT.MVBN	NSA.FD.TH.SG	Suprageniculate Nucleus of Thalamus	nucleus-nucleus	Head Direction Cell Circuit (MVSN -> SUPGEN)
	LPC.HT.SVBN	NSA.FD.TH.SG	Suprageniculate Nucleus of Thalamus	nucleus-nucleus	(unknown reference)
Subcortical
LLC	LPC.HT.IVBN	LLC.HT.CR.VC	Vestibulocerebellum	nucleus-allocortex	(unknown reference)
	LPC.HT.LVBN	LLC.HL.RF.SLRN	Lateral Reticular Nucleus, Subtrigeminal	nucleus-nucleus	(unknown reference)
	LPC.HT.MVBN	LLC.HT.CR.VC	Vestibulocerebellum	nucleus-allocortex	(unknown reference)
LPC	LPC.HT.LVBN	LPC.SC.VH.VL	Ventrolateral Nucleus	nucleus-nucleus	(unknown reference)
	LPC.HT.MVBN	LPC.HT.ABD	Abducens Nucleus	nucleus-nucleus	(unknown reference)
		LPC.MM.OCN	Oculomotor Nucleus	nucleus-nucleus	(unknown reference)
		LPC.MM.TRH	Trochlear Nucleus	nucleus-nucleus	(unknown reference)
		LPC.SC.VH.SAN	Spinal Accessory Nucleus	nucleus-nucleus	(unknown reference)
	LPC.HT.SVBN	LPC.MM.OCN	Oculomotor Nucleus	nucleus-nucleus	(unknown reference)
		LPC.MM.TRH	Trochlear Nucleus	nucleus-nucleus	(unknown reference)
LRC	LPC.HT.IVBN	LRC.HT.PRF.CRF	Caudal Pontine Reticular Nucleus	nucleus-nucleus	Vestibulo-ocular reflex (VOR) (VestibularNuclei -> PPRF, abstract)
	LPC.HT.MVBN	LRC.HL.INM	Intercalated Nucleus of Medulla	nucleus-nucleus	(unknown reference)
		LRC.HL.NPH	Prepositus Nucleus	nucleus-nucleus	Head Direction Cell Circuit (MVSN -> NPRP)
		LRC.MM.DSCH	Darkschewitsch Nucleus	nucleus-nucleus	(unknown reference)

Vision Motor

Component ID	Component Name	Type	Service	Function	Comments
LPC.HT.ABD	Abducens Nucleus	nucleus	LMD	Conjugated movements of both eyes	Motoneurons - to muscle, interneurons - to OCN
LPC.MM.OCN	Oculomotor Nucleus	nucleus	LMD	Change Eye Direction	Muscle nucleus
LPC.MM.TRH	Trochlear Nucleus	nucleus	LMD	Control superior oblique muscles of eyes	Muscle nucleus, change eye direction

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.HT.ABD	LPC.MM.OCN	nucleus-nucleus	Vestibulo-ocular reflex (VOR) (Abducens -> Oculomotor)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LPC	LPC.HT.ABD	LPC.HT.FCM	Facial Motor Nucleus	nucleus-nucleus	Eye blink reflex and pupillary light reflex (Facial -> Abducens)
		LPC.HT.MVBN	Medial Vestibular Nucleus	nucleus-nucleus	(unknown reference)
	LPC.MM.OCN	LPC.HL.TGS.STR	Spinal Trigeminal Nucleus	nucleus-nucleus	Eye blink reflex and pupillary light reflex (SpinalTrigeminal -> Oculomotor)
		LPC.HT.MVBN	Medial Vestibular Nucleus	nucleus-nucleus	(unknown reference)
		LPC.HT.SVBN	Superior Vestibular Nuclei	nucleus-nucleus	(unknown reference)
	LPC.MM.TRH	LPC.HT.MVBN	Medial Vestibular Nucleus	nucleus-nucleus	(unknown reference)
		LPC.HT.SVBN	Superior Vestibular Nuclei	nucleus-nucleus	(unknown reference)
LRC	LPC.HT.ABD	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	nucleus-nucleus	Vestibulo-ocular reflex (VOR) (PPRF -> Abducens, abstract)
		LRC.MM.SC.DEEP	Deep Superior Colliculus	nucleus-nucleus	Retina and superior colliculus targets (SC -> Abducens, abstract)
	LPC.MM.OCN	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	nucleus-nucleus	Global visual system (RF -> OPN, abstract)
		LRC.MM.CJ	Cajal Nucleus	nucleus-nucleus	Eye blink reflex and pupillary light reflex (SupraOculomotor -> Oculomotor, abstract)
		LRC.MM.PT.SL	Sublentiform Nucleus	nucleus-nucleus	(unknown reference)
		LRC.MM.RIMLF	Rostral Interstitial Nucleus of MLF	nucleus-nucleus	Eye blink reflex and pupillary light reflex (SupraOculomotor -> Oculomotor, abstract)
		LRC.MM.SC.DEEP	Deep Superior Colliculus	nucleus-nucleus	Retina and superior colliculus targets (SC -> Oculomotor, abstract)
	LPC.MM.TRH	LRC.MM.CJ	Cajal Nucleus	nucleus-nucleus	(unknown reference)
		LRC.MM.SC.DEEP	Deep Superior Colliculus	nucleus-nucleus	Retina and superior colliculus targets (SC -> Trochlear, abstract)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Target
TSA	LPC.HT.ABD	TARGET.TSA.EYE	Eye	eye-muscle-rotate-vestibular	Eye blink reflex and pupillary light reflex (Abducens -> EYE)
	LPC.MM.OCN	TARGET.TSA.EYE	Eye	eye-muscle-rotate-major-inferior-oblique	Eye blink reflex and pupillary light reflex (Oculomotor -> EYE)
	LPC.MM.TRH	TARGET.TSA.EYE	Eye	eye-muscle-rotate-minor	Extraocular eye muscles (TRC -> EYE)

Vision Sensory

Component ID	Component Name	Type	Service	Function	Comments
LPC.FD.RT	Retina	nucleus	LSC	Spatial decorrelation through center surround inhibition	100:1 cones/rods to ganglion cells aggregation, edge extraction

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Target
TSA	LPC.FD.RT	TARGET.TSA.EYE	Eye	eye-edge-output	Vision Components (EYE -> RT)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NPE	LPC.FD.RT	NPE.FD.TH.MPV	Medial Pulvinar	ganglion-nucleus	Retina and superior colliculus targets (Retina -> Pulvinar, abstract)
NSA	LPC.FD.RT	NSA.FD.LGN	Lateral Geniculate Nucleus	ganglion-nucleus	Geniculate and Extyrageniculate Paths (Retina -> LGN)
Subcortical
LAC	LPC.FD.RT	LAC.FD.HT.SCN	Suprachiasmatic Nucleus	ganglion-nucleus	Targets of retina neurons (Retina -> HT, abstract)
LRC	LPC.FD.RT	LRC.MM.PT.NOT	Nucleus of Optic Tract	ganglion-nucleus	Targets of retina neurons (Retina -> Pretectum, abstract)
		LRC.MM.PT.PON	Pretectal Olivary Nucleus	ganglion-nucleus	Targets of retina neurons (Retina -> Pretectum, abstract)
		LRC.MM.PT.SL	Sublentiform Nucleus	ganglion-nucleus	Targets of retina neurons (Retina -> Pretectum, abstract)
		LRC.MM.SC.SUP	Superficial Superior Colliculus	ganglion-nucleus	Geniculate and Extyrageniculate Paths (Retina -> SC, abstract)

Control Body Extensors

Component ID	Component Name	Type	Service	Function	Comments
LPC.SC.VH.VL	Ventrolateral Nucleus	nucleus	LMD	Innervation of limb muscles	Upper and lower
LPC.SC.VH.VM	Ventromedial Nucleus	nucleus	LMD	Innervation of trunk muscles	Upper and lower

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LPC	LPC.SC.VH.VL	LPC.HT.LVBN	Lateral Vestibular Nuclei	nucleus-nucleus	(unknown reference)
LRC	LPC.SC.VH.VL	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	nucleus-nucleus	Global visual system (RF -> SpinalCord, abstract)
	LPC.SC.VH.VM	LRC.HL.RF.MED	Central Medullary Reticular Nucleus	nucleus-nucleus	(unknown reference)
		LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	nucleus-nucleus	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Subcortical
LAC	LPC.SC.VH.VL	LAC.HL.TGS.PE5	Peritrigeminal Nucleus	nucleus-nucleus	(unknown reference)
Target
TEA	LPC.SC.VH.VL	TARGET.TEA.HAND	Hand	abductor-pollicis-longus-muscle	(unknown reference)
		TARGET.TEA.LEG	Leg	extensor-digitorum-brevis-muscle	(unknown reference)
	LPC.SC.VH.VM	TARGET.TEA.GENITALIA	Genitalia	pubococcygeus-muscle	(unknown reference)
		TARGET.TEA.HAND	Hand	posteriolateral-deltoid-muscle	(unknown reference)
		TARGET.TEA.LEG	Leg	gluteus-maximus-muscle	(unknown reference)
		TARGET.TEA.NECK	Neck	neck-obliquus-capitis-inferior-muscle	(unknown reference)
		TARGET.TEA.RECTUM	Rectum	coccygeus-muscle	(unknown reference)
		TARGET.TEA.SPEAKER	Mouth speaker	larynx-thyrohyoid-muscle	(unknown reference)
		TARGET.TEA.TRUNK	Trunk	semispinalis-capitis-muscle	(unknown reference)

Control Body Generic Flexors

Component ID	Component Name	Type	Service	Function	Comments
LPC.SC.VH.PL	Posterolateral Nucleus	nucleus	LMD	Innervation of limb muscles	Upper and lower proximal muscles
LPC.SC.VH.PM	Posteromedial Nucleus	nucleus	LMD	Innervation of trunk muscles	Upper and lower

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NMA	LPC.SC.VH.PL	NMA.NC.MC	Motor Cortex	neocortex-nucleus	(unknown reference)
	LPC.SC.VH.PM	NMA.NC.MC	Motor Cortex	neocortex-nucleus	(unknown reference)
Subcortical
LLC	LPC.SC.VH.PL	LLC.MM.RD	Red Nucleus	nucleus-nucleus	(unknown reference)
	LPC.SC.VH.PM	LLC.MM.RD	Red Nucleus	nucleus-nucleus	(unknown reference)
LRC	LPC.SC.VH.PL	LRC.HL.PRF.GCR	Gigantocellular Reticular Nucleus	nucleus-nucleus	(unknown reference)
	LPC.SC.VH.PM	LRC.HL.PRF.GCR	Gigantocellular Reticular Nucleus	nucleus-nucleus	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Target
TEA	LPC.SC.VH.PL	TARGET.TEA.HAND	Hand	biceps-muscle	(unknown reference)
		TARGET.TEA.LEG	Leg	gastrocnemius-muscle	(unknown reference)
	LPC.SC.VH.PM	TARGET.TEA.HAND	Hand	anterior-deltoid-muscle	(unknown reference)
		TARGET.TEA.LEG	Leg	leg-adductor-brevis-muscle	(unknown reference)
		TARGET.TEA.TRUNK	Trunk	trunk-abdominal-external-oblique-muscle	(unknown reference)

Control Body Special Flexors

Component ID	Component Name	Type	Service	Function	Comments
LPC.SC.VH.ONF	Onuf's Nucleus	nucleus	LAM	Maintenance of urination and defecation, muscular contraction during orgasm	From Barrington's Nucleus
LPC.SC.VH.RPL	Retroposterolateral Nucleus	nucleus	LMD	Innervation of limbs muscles	Fingers
LPC.SC.VH.SAN	Spinal Accessory Nucleus	nucleus	LMD	Control of neck	Rotate head, continuus from AMB

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NMA	LPC.SC.VH.ONF	NMA.NC.MC	Motor Cortex	neocortex-nucleus	(unknown reference)
	LPC.SC.VH.RPL	NMA.NC.MC	Motor Cortex	neocortex-nucleus	(unknown reference)
Subcortical
LAC	LPC.SC.VH.ONF	LAC.FD.HT.PV	Paraventricular Nucleus	nucleus-nucleus	(unknown reference)
		LAC.HT.BR	Barrington's Nucleus	nucleus-nucleus	Schematic overview of spinobulbospinal micturition reflex pathway (BAR -> ONF)
LPC	LPC.SC.VH.SAN	LPC.HT.MVBN	Medial Vestibular Nucleus	nucleus-nucleus	(unknown reference)
LRC	LPC.SC.VH.ONF	LRC.HL.RA	Retroambigualis Nucleus	nucleus-nucleus	(unknown reference)
	LPC.SC.VH.SAN	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	nucleus-nucleus	Global visual system (RF -> SpinalCord, abstract)
		LRC.MM.SC.DEEP	Deep Superior Colliculus	nucleus-nucleus	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Target
TEA	LPC.SC.VH.ONF	TARGET.TEA.GENITALIA	Genitalia	bulbospongiosus-muscle	(unknown reference)
		TARGET.TEA.RECTUM	Rectum	corrugator-cutis-ani-muscle	(unknown reference)
		TARGET.TEA.URETER	Ureter	external-urethral-sphincter-female	(unknown reference)
	LPC.SC.VH.RPL	TARGET.TEA.HAND	Hand	abductor-digiti-minimi-muscle	(unknown reference)
		TARGET.TEA.LEG	Leg	flexor-longus-digitorum-muscle	(unknown reference)
	LPC.SC.VH.SAN	TARGET.TEA.FEEDER	Mouth feeder	geniohyoid-muscle	(unknown reference)
		TARGET.TEA.NECK	Neck	neck-longus-capitis	(unknown reference)

Control Face Muscles

Component ID	Component Name	Type	Service	Function	Comments
LPC.HL.HYG	Hypoglossal Motor Nucleus	nucleus	LMD	Control of tongue
LPC.HT.FCM	Facial Motor Nucleus	nucleus	LMD	Control of face	Pons
LPC.HT.TRM	Trigeminal Motor Nucleus	nucleus	LMD	Muscles of first branchial arch	Pontine Nuclei, lower face and jaw control, Motor Nucleus of V n.

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LPC	LPC.HT.TRM	LPC.MM.MSTR	Mesencephalic Trigeminal Nucleus	ganglion-nucleus	(unknown reference)
LRC	LPC.HL.HYG	LRC.HT.KFN	Kolliker-Fuse Nucleus	nucleus-nucleus	(unknown reference)
		LRC.HT.NSC	Nucleus Subceruleus	nucleus-nucleus	(unknown reference)
		LRC.HT.PRF.CRF	Caudal Pontine Reticular Nucleus	nucleus-nucleus	Vocal Control (RF -> NucleusXII, abstract)
	LPC.HT.FCM	LRC.HL.TGS.PA5	Paratrigeminal Nucleus	nucleus-nucleus	(unknown reference)
		LRC.HT.PRF.CRF	Caudal Pontine Reticular Nucleus	nucleus-nucleus	Vocal Control (RF -> MotorVII, abstract)
		LRC.HT.PRF.PVR	Parvocellular Reticular Nucleus	nucleus-nucleus	Vocal Control (RF -> MotorVII, abstract)
	LPC.HT.TRM	LRC.HT.PRF.CRF	Caudal Pontine Reticular Nucleus	nucleus-nucleus	Vocal Control (RF -> MotorV, abstract)
		LRC.HT.PRF.PVR	Parvocellular Reticular Nucleus	nucleus-nucleus	Vocal Control (RF -> MotorV, abstract)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Subcortical
LPC	LPC.HT.FCM	LPC.HT.ABD	Abducens Nucleus	nucleus-nucleus	Eye blink reflex and pupillary light reflex (Facial -> Abducens)
Target
TEA	LPC.HL.HYG	TARGET.TEA.FEEDER	Mouth feeder	chondroglossus-muscle	(unknown reference)
	LPC.HT.FCM	TARGET.TEA.FACE	Face	depressor-anguli-oris-muscle	(unknown reference)
		TARGET.TEA.FEEDER	Mouth feeder	buccinator-muscle	(unknown reference)
	LPC.HT.TRM	TARGET.TEA.FEEDER	Mouth feeder	digastric-muscle-trigeminal	(unknown reference)
TSA	LPC.HT.FCM	TARGET.TSA.EAR	Ear	ear-anterior-auricular-muscle	(unknown reference)
		TARGET.TSA.EYE	Eye	eye-muscle-close-conscious-lacrimal	(unknown reference)
		TARGET.TSA.NOSE	Nose	nose-depressor-septi-nasi	(unknown reference)
	LPC.HT.TRM	TARGET.TSA.EAR	Ear	ear-tensor-tympani-muscle	(unknown reference)

Auditory Sense

Component ID	Component Name	Type	Service	Function	Comments
LPC.HL.DCOCH	Dorsal Cochlear Nucleus	nucleus	LSC	Analyzes quality of sound, picks apart tiny frequency differences between close sounds
LPC.HL.VCOCH	Ventral Cochlear Nucleus	nucleus	LSC	determine direction sound came from, time-sensitive localization
LPC.HT.PN.LL	Nuclei of Lateral Lemniscus	nucleus	LSC	Decoding of amplitude modulated sounds	Prominent columnar organization, cochlea to IC
LPC.MM.CIC	Central Nucleus of Inferior Colliculus	nucleus	LSC	Integrate and relay auditory information to cortex, detection of pitch, spatial localization by binaural hearing
LPC.MM.SOC	Superior Olivary Complex	nucleus	LSC	Bilateral Audition	Projections from both left and right ABA.CN
LPC.PN.SG.SP	Spiral Ganglion	sensory ganglion	LSC	Auditory patterns	Fibres from bipolar cells in the spiral ganglion consist of peripheral branches that end in the organ of Corti and central branches that end in the ventral and dorsal cochlear nuclei

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.HL.DCOCH	LPC.HT.PN.LL	nucleus-nucleus	Five Parallel Auditory Pathways (OC -> VNLL, abstract)
	LPC.MM.CIC	nucleus-nucleus	Five Parallel Auditory Pathways (DCN -> ICC, abstract)
LPC.HL.VCOCH	LPC.MM.SOC	nucleus-nucleus	Auditory System in Brain (Cochlea -> Olive, abstract)
LPC.HT.PN.LL	LPC.MM.CIC	nucleus-nucleus	Five Parallel Auditory Pathways (VNLL -> ICC, abstract)
LPC.MM.SOC	LPC.HT.PN.LL	nucleus-nucleus	Five Parallel Auditory Pathways (LSO -> DNLL)
	LPC.MM.CIC	nucleus-nucleus	Auditory System in Brain (Olive -> IC, abstract)
LPC.PN.SG.SP	LPC.HL.DCOCH	ganglion-nucleus	Auditory System in Brain (CochleaGanglion -> Cochlea, abstract)
	LPC.HL.VCOCH	ganglion-nucleus	Auditory System in Brain (CochleaGanglion -> Cochlea, abstract)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NSA	LPC.MM.CIC	NSA.NC.TTG.A1	Primary Auditory Cortex	neocortex-nucleus	Visual-Auditory Interactions in Tectum (AC -> IC, abstract)
Subcortical
FAM	LPC.MM.CIC	FAM.FT.AM.LAVM	Ventromedial Amygdaloid Nucleus	nucleus-nucleus	Visual-Auditory Interactions in Tectum (AM -> IC, abstract)
Target
TSA	LPC.PN.SG.SP	TARGET.TSA.EAR	Ear	ear-inner-hair-cells	Auditory System Model (Ear -> CochleaGanglion)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NSA	LPC.MM.CIC	NSA.FD.TH.MGB	Medial Geniculate Body	nucleus-nucleus	Auditory System in Brain (IC -> MGB, abstract)
Subcortical
LRC	LPC.HL.VCOCH	LRC.MM.CJ	Cajal Nucleus	nucleus-nucleus	(unknown reference)
	LPC.MM.CIC	LRC.MM.EIC	External Nucleus of Inferior Colliculus	nucleus-nucleus	Five Parallel Auditory Pathways (ICC -> ICx, abstract)
Target
TSA	LPC.MM.SOC	TARGET.TSA.EAR	Ear	ear-outer-hair-cells	Five Parallel Auditory Pathways (VNTB -> Cochlea)

Common Body Sensations

Component ID	Component Name	Type	Service	Function	Comments
LPC.SC.LH.LCV	Lateral Cervical Nucleus	nucleus	LLI	Relay Low-threshold Mechanoreceptors to CR	From Lamina V
LPC.SC.PH.NP	Proprius Nucleus	nucleus	LLI	Relay light touch, pain and temperature information	With Clarke's Nucleus sensing fine touch and proprioception

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.SC.PH.NP	LPC.SC.LH.LCV	nucleus-nucleus	(unknown reference)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LPC	LPC.SC.PH.NP	LPC.PN.SG.LDRG	Lower Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)
		LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)
		LPC.SC.PH.LSG	Lower Substantia Gelatinosa	nucleus-nucleus	(unknown reference)
		LPC.SC.PH.USG	Upper Substantia Gelatinosa	nucleus-nucleus	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NSA	LPC.SC.LH.LCV	NSA.FD.TH.VPL	Ventral Posterolateral Nucleus	nucleus-nucleus	(unknown reference)
	LPC.SC.PH.NP	NSA.FD.TH.VPL	Ventral Posterolateral Nucleus	nucleus-nucleus	(unknown reference)
Subcortical
LLC	LPC.SC.PH.NP	LLC.HL.IO	Inferior Olivary Nucleus	nucleus-nucleus	(unknown reference)

Lower Body Conscious Sensations

Component ID	Component Name	Type	Service	Function	Comments
LPC.HL.GR	Gracile Nucleus	nucleus	LSM	Carry epicritic, kinesthetic, and conscious proprioceptive information from lower body
LPC.PN.SG.LDRG	Lower Dorsal Root Ganglion	sensory ganglion	LSC	Integration of afferent signaling from lower thoracic and lumbosacral somatic and viscera	T7-T12,L1-L5,S1-S5,CX
LPC.SC.PH.LMG	Lower Marginal Nucleus	nucleus	LSM	Relay information related to pain and temperature sensation - T7-T12,L1-L5,S1-S5,CX
LPC.SC.PH.LSG	Lower Substantia Gelatinosa	nucleus	LSM	Relay for C-fibers of slowly conducting, poorly localized pain sensation - T7-T12,L1-L5,S1-S5,CX

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.PN.SG.LDRG	LPC.HL.GR	ganglion-nucleus	(unknown reference)
	LPC.SC.PH.LMG	ganglion-nucleus	(unknown reference)
	LPC.SC.PH.LSG	ganglion-nucleus	(unknown reference)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LMC	LPC.SC.PH.LMG	LMC.HL.RP.PL	Raphe Pallidus Nucleus	nucleus-nucleus-5HT	(unknown reference)
	LPC.SC.PH.LSG	LMC.HL.RP.MG	Raphe Magnus Nucleus	nucleus-nucleus-5HT	(unknown reference)
Target
TEA	LPC.PN.SG.LDRG	TARGET.TEA.GENITALIA	Genitalia	utetovaginal-visceral-receptors	(unknown reference)
		TARGET.TEA.LEG	Leg	leg-somatic-receptors	(unknown reference)
		TARGET.TEA.LIVER	Liver	visceral-receptors	(unknown reference)
		TARGET.TEA.RECTUM	Rectum	large-intestine-visceral-receptors	(unknown reference)
		TARGET.TEA.STOMACH	Stomach	stomach-nutrition-sensor	(unknown reference)
		TARGET.TEA.TRUNK	Trunk	trunk-lower-somatic-receptors	(unknown reference)
		TARGET.TEA.URETER	Ureter	ureter-visceral-receptors	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NDM	LPC.SC.PH.LMG	NDM.FD.TH.SM	Submedial Nucleus of Thalamus	nucleus-nucleus	(unknown reference)
NSA	LPC.HL.GR	NSA.FD.TH.VPL	Ventral Posterolateral Nucleus	nucleus-nucleus	(unknown reference)
	LPC.SC.PH.LMG	NSA.FD.TH.VPI	Ventral Posteroinferior Nucleus	nucleus-nucleus	(unknown reference)
		NSA.FD.TH.VPL	Ventral Posterolateral Nucleus	nucleus-nucleus	Thalamocortical relationships (sVPL -> VPL, abstract)
	LPC.SC.PH.LSG	NSA.FD.TH.VPI	Ventral Posteroinferior Nucleus	nucleus-nucleus	(unknown reference)
Subcortical
FEC	LPC.SC.PH.LMG	FEC.FD.TH.LI	Limitans Nucleus of Thalamus	nucleus-nucleus	(unknown reference)
LPC	LPC.PN.SG.LDRG	LPC.SC.IZ.IMM	Intermediomedial Nucleus	ganglion-nucleus	(unknown reference)
		LPC.SC.PH.CL	Clarke Nucleus	ganglion-nucleus	(unknown reference)
		LPC.SC.PH.NP	Proprius Nucleus	ganglion-nucleus	(unknown reference)
	LPC.SC.PH.LSG	LPC.SC.PH.NP	Proprius Nucleus	nucleus-nucleus	(unknown reference)
LRC	LPC.HL.GR	LRC.MM.SC.INT	Intermediate Superior Colliculus	nucleus-nucleus	(unknown reference)

Upper Body Conscious Sensations

Component ID	Component Name	Type	Service	Function	Comments
LPC.HL.CU	Cuneate Nucleus	nucleus	LSM	Carry fine touch and proprioceptive information from upper body
LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	sensory ganglion	LSC	Integration of afferent signaling from cervical and upper thoracic somatic and viscera	C1-C8, T1-T6
LPC.SC.PH.UMG	Upper Marginal Nucleus	nucleus	LSM	Relay information related to pain and temperature sensation - C1-C8,T1-T6
LPC.SC.PH.USG	Upper Substantia Gelatinosa	nucleus	LSM	Relay for C-fibers of slowly conducting, poorly localized pain sensation - C1-C8,T1-T6

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.PN.SG.UDRG	LPC.HL.CU	ganglion-nucleus	(unknown reference)
	LPC.SC.PH.UMG	ganglion-nucleus	(unknown reference)
	LPC.SC.PH.USG	ganglion-nucleus	(unknown reference)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LMC	LPC.SC.PH.UMG	LMC.HL.RP.PL	Raphe Pallidus Nucleus	nucleus-nucleus-5HT	(unknown reference)
	LPC.SC.PH.USG	LMC.HL.RP.MG	Raphe Magnus Nucleus	nucleus-nucleus-5HT	(unknown reference)
Target
TEA	LPC.PN.SG.UDRG	TARGET.TEA.BREAST	Breast	breast-skin-receptors	(unknown reference)
		TARGET.TEA.FACE	Face	face-parotid-skin	(unknown reference)
		TARGET.TEA.HAND	Hand	hand-somatic-receptors	(unknown reference)
		TARGET.TEA.HEART	Heart	heart-visceral	(unknown reference)
		TARGET.TEA.LUNG	Lung	pericardium-pleura-receptors	(unknown reference)
		TARGET.TEA.NECK	Neck	neck-low-cutaneous-receptors	(unknown reference)
		TARGET.TEA.TRUNK	Trunk	trunk-upper-somatic-receptors	(unknown reference)
TSA	LPC.PN.SG.UDRG	TARGET.TSA.EAR	Ear	ear-external-skin	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NDM	LPC.SC.PH.UMG	NDM.FD.TH.SM	Submedial Nucleus of Thalamus	nucleus-nucleus	(unknown reference)
NSA	LPC.HL.CU	NSA.FD.TH.VPL	Ventral Posterolateral Nucleus	nucleus-nucleus	(unknown reference)
	LPC.SC.PH.UMG	NSA.FD.TH.VPI	Ventral Posteroinferior Nucleus	nucleus-nucleus	(unknown reference)
		NSA.FD.TH.VPL	Ventral Posterolateral Nucleus	nucleus-nucleus	Thalamocortical relationships (sVPL -> VPL, abstract)
	LPC.SC.PH.USG	NSA.FD.TH.VPI	Ventral Posteroinferior Nucleus	nucleus-nucleus	(unknown reference)
Subcortical
FEC	LPC.SC.PH.UMG	FEC.FD.TH.LI	Limitans Nucleus of Thalamus	nucleus-nucleus	(unknown reference)
LLC	LPC.HL.CU	LLC.HT.CR.SC	Spinocerebellum	nucleus-allocortex	(unknown reference)
	LPC.PN.SG.UDRG	LLC.SC.IZ.CCV	Central Cervical Nucleus	ganglion-nucleus	(unknown reference)
LPC	LPC.PN.SG.UDRG	LPC.HL.ACU	Accessory Cuneate Nucleus	ganglion-nucleus	(unknown reference)
		LPC.HL.TGS.STR	Spinal Trigeminal Nucleus	ganglion-nucleus	(unknown reference)
		LPC.SC.IZ.CBS	Centrobasalis Nucleus	ganglion-nucleus	(unknown reference)
		LPC.SC.IZ.IMM	Intermediomedial Nucleus	ganglion-nucleus	(unknown reference)
		LPC.SC.PH.CL	Clarke Nucleus	ganglion-nucleus	(unknown reference)
		LPC.SC.PH.NP	Proprius Nucleus	ganglion-nucleus	(unknown reference)
	LPC.SC.PH.USG	LPC.SC.PH.NP	Proprius Nucleus	nucleus-nucleus	(unknown reference)
LRC	LPC.HL.CU	LRC.MM.SC.INT	Intermediate Superior Colliculus	nucleus-nucleus	(unknown reference)

Sensory Face

Component ID	Component Name	Type	Service	Function	Comments
LPC.HL.TGS.STR	Spinal Trigeminal Nucleus	nucleus	LSM	Discriminative sensation and light touch of face, conscious proprioception	Pontine Nuclei, part of cranial nerve nuclei, ear
LPC.HT.PN.PTR	Principal Trigeminal Nucleus	nucleus	LSM	Facial Somatic Sensations	Upper, maxillary, ophthalmic
LPC.MM.MSTR	Mesencephalic Trigeminal Nucleus	sensory ganglion	LSC	unconscious proprioception from muscle spindles; facial somatic sensations from muscles of mastication, monosynaptic masticatory reflex	Lower, mandibular - ganglion; mandible and maxilla - tooth pulp, surrounding gingiva, periodontal membrane and a vast portion of the oral mucosa
LPC.PN.SG.TRG	Trigeminal Ganglion	sensory ganglion	LSC	Integration of external auditory meatus (auricular branch), cranial meninges (meningeal branch), and external surface of tympanic membrane	sensory fibers of ophthalmic, maxillary, mandibular nerves to principal trigeminal nucleus

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.HT.PN.PTR	LPC.HL.TGS.STR	nucleus-nucleus	Eye blink reflex and pupillary light reflex (PrincipalTrigeminal -> SpinalTrigeminal)
LPC.MM.MSTR	LPC.HT.PN.PTR	ganglion-nucleus	(unknown reference)
LPC.PN.SG.TRG	LPC.HL.TGS.STR	ganglion-nucleus	(unknown reference)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LPC	LPC.HL.TGS.STR	LPC.PN.SG.GNG	Geniculate Ganglion	ganglion-nucleus	(unknown reference)
		LPC.PN.SG.JUG	Jugular Ganglion	ganglion-nucleus	(unknown reference)
		LPC.PN.SG.PET	Petrosal Ganglion	ganglion-nucleus	(unknown reference)
		LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)
Target
TEA	LPC.MM.MSTR	TARGET.TEA.FEEDER	Mouth feeder	masticatory-unconscious-muscle-spindles	(unknown reference)
	LPC.PN.SG.TRG	TARGET.TEA.FACE	Face	face-skin	(unknown reference)
		TARGET.TEA.FEEDER	Mouth feeder	teeth	(unknown reference)
		TARGET.TEA.PROTECTOR	Immunity glands and meninges	lingual-tonsil	(unknown reference)
TSA	LPC.MM.MSTR	TARGET.TSA.EYE	Eye	eye-visceral	(unknown reference)
		TARGET.TSA.NOSE	Nose	nose-proprioceptors	(unknown reference)
	LPC.PN.SG.TRG	TARGET.TSA.EAR	Ear	ear-acoustic-meatus-skin	(unknown reference)
		TARGET.TSA.EYE	Eye	eye-lacrimal-gland-conjunctiva-receptors	(unknown reference)
		TARGET.TSA.NOSE	Nose	nose-somatic	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NSA	LPC.HT.PN.PTR	NSA.FD.TH.VPM	Ventral Posteromedial Nucleus	nucleus-nucleus	Trigeminal Nuclei (CSN -> VPM)
Subcortical
LLC	LPC.HL.TGS.STR	LLC.HT.PRF.PDT	Pontine Reticulotegmental Nucleus	nucleus-nucleus	Eye blink reflex and pupillary light reflex (SpinalTrigeminal -> RF, abstract)
LPC	LPC.HL.TGS.STR	LPC.MM.OCN	Oculomotor Nucleus	nucleus-nucleus	Eye blink reflex and pupillary light reflex (SpinalTrigeminal -> Oculomotor)
	LPC.MM.MSTR	LPC.HT.TRM	Trigeminal Motor Nucleus	ganglion-nucleus	(unknown reference)
LRC	LPC.HL.TGS.STR	LRC.HL.PRF.GCR	Gigantocellular Reticular Nucleus	nucleus-nucleus	(unknown reference)
		LRC.MM.SC.INT	Intermediate Superior Colliculus	nucleus-nucleus	(unknown reference)

Pain Sensations

Component ID	Component Name	Type	Service	Function	Comments
LPC.FD.TH.PV	Paraventricular Nucleus of Thalamus	nucleus	FAU	Direct behavior toward a particular outcome over a range of outcomes	Projects like PT, but more to BNST, AM
LPC.HT.PRF.PB	Parabrachial Nucleus	nucleus	LUS	Source of short-latency nociceptive input; sense of physiological condition of body well-being or interoception	major relay site for visceral afferents ascending through ventrobasal thalamus and terminating in insular cortex

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	LPC.HT.PRF.PB	NCP.NC.AL.SGCG	Subgenual Cingulate Cortex	neocortex-nucleus	Global visual system (FrontalCortex -> RF, abstract)
Subcortical
FAM	LPC.FD.TH.PV	FAM.FT.AM.LAVM	Ventromedial Amygdaloid Nucleus	nucleus-nucleus	Oculomotor decision-making (AMYG -> Thalamus, abstract)
		FAM.FT.SEP.LT	Lateral Septal Nucleus	nucleus-nucleus-gaba	(unknown reference)
	LPC.HT.PRF.PB	FAM.FT.IPAC.MED	Medial Interstitial Anterior Commissural Nucleus	nucleus-nucleus	(unknown reference)
LMC	LPC.FD.TH.PV	LMC.MM.PAG	Periaqueductal Gray Matter	nucleus-nucleus-ENK	(unknown reference)
		LMC.MM.RP.DRN	Dorsal Raphe Nucleus	nucleus-nucleus-5HT	(unknown reference)
LPC	LPC.HT.PRF.PB	LPC.HL.SOL	Solitary Nucleus	nucleus-nucleus	Amygdalar disruption of prefrontal cortex (SOL -> PB)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NCP	LPC.HT.PRF.PB	NCP.NC.INS.PIC	Posterior Insular Cortex	nucleus-neocortex	Gustatory sensory system of rat and macaque (PB -> Gud, abstract)
NDM	LPC.FD.TH.PV	NDM.NC.AL.ROFCS	Sulcal Rostral Orbitofrontal Cortex	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
		NDM.NC.AL.VMPFC	Ventromedial Prefrontal Cortex	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
NSA	LPC.HT.PRF.PB	NSA.FD.TH.VPI	Ventral Posteroinferior Nucleus	nucleus-nucleus	(unknown reference)
		NSA.FD.TH.VPM	Ventral Posteromedial Nucleus	nucleus-nucleus	Gustatory sensory system of rat and macaque (PB -> VPMpc)
Subcortical
FAM	LPC.FD.TH.PV	FAM.FT.BNST	Bed Nucleus of Stria Terminalis	nucleus-nucleus	(unknown reference)
	LPC.HT.PRF.PB	FAM.FT.AM.CEL	Central Amygdaloid Nucleus, lateral subdivision	nucleus-nucleus	Amygdalar disruption of prefrontal cortex (PB -> AM, abstract)
FEC	LPC.FD.TH.PV	FEC.FT.ACC.CORE	Nucleus Accumbens Core	nucleus-nucleus	(unknown reference)
	LPC.HT.PRF.PB	FEC.FT.ACC.SH	Nucleus Accumbens Shell	nucleus-nucleus	Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)
		FEC.FT.PU.LT	Dorsal Putamen Lateral	nucleus-nucleus	Bowels control brain: gut hormones and obesity (PBN -> DS, abstract)
		FEC.FT.PU.MED	Dorsal Putamen Medial	nucleus-nucleus	Bowels control brain: gut hormones and obesity (PBN -> DS, abstract)
FMM	LPC.FD.TH.PV	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	nucleus-neocortex	Contributions of Diencephalon to Recognition Memory (MID -> EC, abstract)
		FMM.NC.PH.PER	Perirhinal Cortex	nucleus-neocortex	Contributions of Diencephalon to Recognition Memory (MID -> Perirhinal, abstract)
LAC	LPC.FD.TH.PV	LAC.FD.HT.PO	Preoptic Nucleus	nucleus-nucleus	(unknown reference)
		LAC.FD.HT.SCN	Suprachiasmatic Nucleus	nucleus-nucleus	(unknown reference)
	LPC.HT.PRF.PB	LAC.FD.HT.DM	Dorsomedial Hypothalamic Nucleus	nucleus-nucleus	Food-entrainable circadian oscillator (PBN -> DMH)
		LAC.HL.VGN	Vagus Nucleus	nucleus-nucleus	Physiology and pathophysiology of lower urinary tract (PBN -> DVM)

Smell Senses

Component ID	Component Name	Type	Service	Function	Comments
LPC.FT.AOB	Accessory Olfactory Bulb	nucleus	LSM	Pheromones sampling
LPC.FT.AON	Anterior Olfactory Nucleus	nucleus	LSM	Regulate odor information flow
LPC.FT.MOB	Main Olfactory Bulb	nucleus	LSM	Volatile odor patterns	generate spatiotemporal neural code, in=glomeruli -> 1000x1 -> out=mitral
LPC.PN.SG.MOE	Main Olfactory Epithelium	sensory ganglion	LSC	Sensing volatile odors
LPC.PN.SG.VNO	Vomeronasal Organ	sensory ganglion	LSC	Sensing non-volatile pheromones

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.FT.AON	LPC.FT.MOB	nucleus-nucleus	(unknown reference)
LPC.PN.SG.MOE	LPC.FT.AOB	ganglion-nucleus	(unknown reference)
	LPC.FT.MOB	ganglion-nucleus	(unknown reference)
LPC.PN.SG.VNO	LPC.FT.AOB	ganglion-nucleus	(unknown reference)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LAC	LPC.FT.MOB	LAC.FD.HT.TBM	Tuberomammillary Nucleus	nucleus-nucleus	(unknown reference)
Target
TSA	LPC.PN.SG.MOE	TARGET.TSA.NOSE	Nose	nose-volatile	(unknown reference)
	LPC.PN.SG.VNO	TARGET.TSA.NOSE	Nose	nose-nonvolatile	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NSA	LPC.FT.AON	NSA.NC.PH.PIR	Piriform Cortex	nucleus-neocortex	KIV model of cortico-hippocampal formation with subcortical projections for motor actions (AON -> PC)
	LPC.FT.MOB	NSA.NC.PH.PRP	Prepyriform Cortex	nucleus-neocortex	(unknown reference)
Subcortical
FAM	LPC.FT.AOB	FAM.FT.AM.COP	Posterior Cortical Amygdaloid Nucleus	nucleus-nucleus	(unknown reference)
		FAM.FT.AM.MEA	Medial Anterior Amygdaloid Nucleus	nucleus-nucleus	(unknown reference)
	LPC.FT.MOB	FAM.FT.AM.COA	Anterior Cortical Amygdaloid Nucleus	nucleus-nucleus	(unknown reference)

Taste Senses

Component ID	Component Name	Type	Service	Function	Comments
LPC.HL.SOL	Solitary Nucleus	nucleus	LSM	Carry taste buds, thoracic and abdominal viscera	c.n. VII, IX, X
LPC.PN.SG.GNG	Geniculate Ganglion	sensory ganglion	LSC	Trophic support for survival	Innervation taste buds, ear skin
LPC.PN.SG.JUG	Jugular Ganglion	sensory ganglion	LSC	Integration of external auditory meatus (auricular branch), cranial meninges (meningeal branch), and external surface of tympanic membrane	to Sensory Trigeminal Nucleus
LPC.PN.SG.NOD	Nodose Ganglion	sensory ganglion	LSC	Integration of afferent signaling from viscera	caudal SOL - larynx, trachea, gut, and aortic arch receptors; rostral SOL - taste receptors of posterior oral cavity
LPC.PN.SG.PET	Petrosal Ganglion	sensory ganglion	LSC	Integration of afferent signaling from viscera	mucous membranes of pharynx, middle ear, carotid body and sinus, taste sensor on the posterior third of tongue to SOL

Internal Region Connections:

Source Region	Target Region	Type	Reference
LPC.PN.SG.GNG	LPC.HL.SOL	ganglion-nucleus	(unknown reference)
LPC.PN.SG.JUG	LPC.HL.SOL	ganglion-nucleus	(unknown reference)
LPC.PN.SG.NOD	LPC.HL.SOL	ganglion-nucleus	(unknown reference)
LPC.PN.SG.PET	LPC.HL.SOL	ganglion-nucleus	(unknown reference)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
FAM	LPC.HL.SOL	FAM.FT.AM.CEL	Central Amygdaloid Nucleus, lateral subdivision	nucleus-nucleus	(unknown reference)
		FAM.FT.IPAC.MED	Medial Interstitial Anterior Commissural Nucleus	nucleus-nucleus	(unknown reference)
LAC	LPC.HL.SOL	LAC.FD.HT.VM	Ventromedial Hypothalamic Nucleus	nucleus-nucleus	Bowels control brain: gut hormones and obesity (VMN -> NTS)
Target
TEA	LPC.PN.SG.GNG	TARGET.TEA.FEEDER	Mouth feeder	soft-palate-sparse-taste-receptors	(unknown reference)
	LPC.PN.SG.JUG	TARGET.TEA.LUNG	Lung	pulmonary-stretch-receptors	(unknown reference)
		TARGET.TEA.PROTECTOR	Immunity glands and meninges	cranial-meninges	(unknown reference)
		TARGET.TEA.SPEAKER	Mouth speaker	palatine-tonsil-receptors	(unknown reference)
	LPC.PN.SG.NOD	TARGET.TEA.FEEDER	Mouth feeder	epiglottis-taste-buds	(unknown reference)
		TARGET.TEA.HEART	Heart	heart-aorta-baroreceptors	(unknown reference)
		TARGET.TEA.LIVER	Liver	glucose-and-osmoreceptors	(unknown reference)
		TARGET.TEA.LUNG	Lung	pulmonary-neuroepithelial-bodies	(unknown reference)
		TARGET.TEA.STOMACH	Stomach	colon	(unknown reference)
	LPC.PN.SG.PET	TARGET.TEA.HEART	Heart	heart-carotid-baroreceptors	(unknown reference)
TSA	LPC.PN.SG.GNG	TARGET.TSA.EAR	Ear	ear-somatic	(unknown reference)
	LPC.PN.SG.JUG	TARGET.TSA.EAR	Ear	ear-visceral	(unknown reference)
	LPC.PN.SG.NOD	TARGET.TSA.NOSE	Nose	nose-visceral-vagus	(unknown reference)
	LPC.PN.SG.PET	TARGET.TSA.EAR	Ear	ear-timpanic-cavity	(unknown reference)
		TARGET.TSA.NOSE	Nose	nose-visceral-pharynx	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NSA	LPC.HL.SOL	NSA.FD.TH.VPL	Ventral Posterolateral Nucleus	nucleus-nucleus	Amygdalar disruption of prefrontal cortex (SOL -> TH, abstract)
		NSA.FD.TH.VPM	Ventral Posteromedial Nucleus	nucleus-nucleus	Thalamocortical relationships (sVPM -> VPM)
Subcortical
FEC	LPC.HL.SOL	FEC.FT.ACC.SH	Nucleus Accumbens Shell	nucleus-nucleus	Bowels control brain: gut hormones and obesity (NTS -> NAc, abstract)
LAC	LPC.HL.SOL	LAC.FD.HT.AR	Arcuate Nucleus of Hypothalamus	nucleus-nucleus	(unknown reference)
		LAC.FD.HT.DM	Dorsomedial Hypothalamic Nucleus	nucleus-nucleus	Food-entrainable circadian oscillator (NTS -> DMH)
		LAC.FD.HT.LTN	Lateral Hypothalamic Nucleus	nucleus-nucleus	Schematic of hypothalamic circuitry underlying satiety (NTS -> LHA)
		LAC.FD.HT.PV	Paraventricular Nucleus	nucleus-nucleus	(unknown reference)
		LAC.FD.HT.SO	Supraoptic Nucleus	nucleus-nucleus	(unknown reference)
LMC	LPC.HL.SOL	LMC.MM.VTA	Ventral Tegmental Area	nucleus-nucleus	Bowels control brain: gut hormones and obesity (NTS -> VTA)
LPC	LPC.HL.SOL	LPC.HL.AMB	Ambiguus Nucleus	nucleus-nucleus	(unknown reference)
		LPC.HT.PRF.PB	Parabrachial Nucleus	nucleus-nucleus	Amygdalar disruption of prefrontal cortex (SOL -> PB)
	LPC.PN.SG.GNG	LPC.HL.TGS.STR	Spinal Trigeminal Nucleus	ganglion-nucleus	(unknown reference)
	LPC.PN.SG.JUG	LPC.HL.TGS.STR	Spinal Trigeminal Nucleus	ganglion-nucleus	(unknown reference)
	LPC.PN.SG.PET	LPC.HL.TGS.STR	Spinal Trigeminal Nucleus	ganglion-nucleus	(unknown reference)
LRC	LPC.HL.SOL	LRC.HL.RA	Retroambigualis Nucleus	nucleus-nucleus	(unknown reference)
		LRC.HT.KFN	Kolliker-Fuse Nucleus	nucleus-nucleus	(unknown reference)

Unconscious Cerebellar Sensations

Component ID	Component Name	Type	Service	Function	Comments
LPC.HL.ACU	Accessory Cuneate Nucleus	nucleus	LSM	receives input from cervical spinal nerves and transmits that information to cerebellum	upper extremity equivalent of Clarke's column
LPC.SC.IZ.CBS	Centrobasalis Nucleus	nucleus	LLI	Unconscious proprioception to CR	Upper extremity, relay motor feedback to CR, major site of termination for dorsal root fibers
LPC.SC.IZ.IMM	Intermediomedial Nucleus	nucleus	LLI	Visceral sensory	ventral spinocerebellar tract; to vermis
LPC.SC.PH.CL	Clarke Nucleus	nucleus	LLI	Unconscious Proprioception	To CR

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
LMC	LPC.SC.IZ.IMM	LMC.HL.RP.OB	Raphe Obscurus Nucleus	nucleus-nucleus-5HT	(unknown reference)
LPC	LPC.HL.ACU	LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)
	LPC.SC.IZ.CBS	LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)
	LPC.SC.IZ.IMM	LPC.PN.SG.LDRG	Lower Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)
		LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)
	LPC.SC.PH.CL	LPC.PN.SG.LDRG	Lower Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)
		LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	ganglion-nucleus	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Subcortical
LLC	LPC.HL.ACU	LLC.HT.CR.SC	Spinocerebellum	nucleus-allocortex	(unknown reference)
	LPC.SC.IZ.CBS	LLC.HT.CR.SC	Spinocerebellum	nucleus-allocortex	(unknown reference)
	LPC.SC.IZ.IMM	LLC.HL.RF.PLRN	Lateral Reticular Nucleus, Parvocellular	nucleus-nucleus	(unknown reference)
		LLC.HT.CR.SC	Spinocerebellum	nucleus-allocortex	(unknown reference)
	LPC.SC.PH.CL	LLC.HL.ARC	Arcuate Nucleus of Medulla	nucleus-nucleus	(unknown reference)
		LLC.HT.CR.SC	Spinocerebellum	nucleus-allocortex	(unknown reference)
		LLC.HT.PN.PBB	Pontobulbar Body	nucleus-nucleus	(unknown reference)
		LLC.MM.CNF	Cuneiform Nucleus	nucleus-nucleus	(unknown reference)

Thirdparty Circuits

(generated)

• Eye blink reflex and pupillary light reflex - see Reference

• Five Parallel Auditory Pathways - see Reference

• Vocal Control - see Reference

• Retina and superior colliculus targets - see Reference

• Extraocular eye muscles - see Reference

• Vestibulo-ocular reflex (VOR) - see Reference

• Vision Components - see Reference

• Auditory System Model - see Reference

• Auditory System in Brain - see Reference

• Physiology and pathophysiology of lower urinary tract - see Reference

• Trigeminal Nuclei - see Reference

• Gustatory sensory system of rat and macaque - see Reference

• Food-entrainable circadian oscillator - see Reference

• Bowels control brain: gut hormones and obesity - see Reference

• Amygdalar disruption of prefrontal cortex - see Reference

• Thalamocortical relationships - see Reference

• Global visual system - see Reference

• Schematic overview of spinobulbospinal micturition reflex pathway - see Reference

• Visual-Auditory Interactions in Tectum - see Reference

• Horizontal saccades and smooth pursuit movements - see Reference

• Head Direction Cell Circuit - see Reference

• Saccades and smooth movements (unknown reference)

• Schematic of hypothalamic circuitry underlying satiety - see Reference

• KIV model of cortico-hippocampal formation with subcortical projections for motor actions - see Reference

• Dorsal midline thalamus - see Reference

• Medial prefrontal network - see Reference

• Visual perception abstraction - see Reference

• Visual Dorsal Pathway - see Reference

• Saccadic Vision - see Reference

• Targets of retina neurons - see Reference

• Paths from Retina to Parietal Cortex and IT - see Reference

• Geniculate and Extyrageniculate Paths - see Reference

• Eye muscles - see Reference

• Eye muscle directions - see Reference

• Eye movement terminology - see Reference

References

(generated)

• http://neuroscience.uth.tmc.edu/s3/chapter07.html
• http://lifeboat.com/ex/law.of.accelerating.returns
• http://www.frontiersin.org/neuroanatomy/10.3389/fnana.2011.00034/full
• http://unifiedtao-en.blogspot.ru/2011/03/what-we-see-of-tao.html
• http://what-when-how.com/neuroscience/the-cranial-nerves-organization-of-the-central-nervous-system-part-4
• http://www.neuroanatomy.wisc.edu/virtualbrain/BrainStem/13VNAN.html
• http://www.sciencedirect.com/science/article/pii/S1359644605035427
• http://www.benbest.com/science/anatmind/anatmd6.html
• http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
• http://www.lookfordiagnosis.com/mesh_info.php?term=Trigeminal+Nucleilang=1
• http://www.sciencedirect.com/science/article/pii/S0149763401000215
• http://www.pnas.org/content/103/32/12150/F7.expansion.html
• http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
• http://neuropolitics.org/defaultmay10.asp
• http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/
• http://www.sciencedirect.com/science/article/pii/S0959438808001566
• http://jp.physoc.org/content/557/1/287/F9.expansion.html
• http://f1000research.com/articles/2-20/v1
• http://www.sciencedirect.com/science/article/pii/S0006899301025987
• http://www.scholarpedia.org/article/Head_direction_cells
• http://neuroscience.uth.tmc.edu/s4/chapter04.html
• http://www.sciencedirect.com/science/article/pii/S1571064507000243
• http://www.sciencedirect.com/science/article/pii/S0149763415002055
• http://www.nature.com/npp/journal/v35/n1/fig_tab/npp2009104f10.html
• http://asweknowit.ca/evcult/NatIntel/nat_intel.shtml
• http://www.hindawi.com/journals/nri/2012/719056
• http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html
• http://www.rci.rutgers.edu/~uzwiak/AnatPhys/Vision.htm
• http://thebrain.mcgill.ca/flash/i/i_02/i_02_cr/i_02_cr_vis/i_02_cr_vis.html
• http://www.sciencedirect.com/science/article/pii/S0387760401003308
• http://etc.usf.edu/clipart/53700/53763/53763_eye.htm
• http://meded.ucsd.edu/clinicalmed/eyes.htm