BrainRegionNDM FD TH MDM
Medial Mediodorsal Nucleus of Thalamus
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This page covers biological details of component Medial Mediodorsal Nucleus of Thalamus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Thalamus (FD.TH) -> Cognitive Thalamus (FD.TH.CR) -> Mediodorsal Nucleus of Thalamus (FD.TH.MD) -> Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM) (see Mind Maps)
- Type: nucleus
- Brain area: Neocortical Brain - Decision Making Area
- Role: thalamic.cortex.reinforce
- Function: relay emotional attention to orbitofrontal cortex
- Notes to function: orbitofrontal cortex (BA12,13) defined by MDm projection; relay AM-Bp to OFC; OFCm - subjective pleasantness, OFCl - subjective unpleasantness
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Reference |
FAM | FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | excitatory-glu | Prefrontal Cortex (PFC) in emotional behavior (AM -> TH, abstract) |
FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | excitatory-glu | Amygdala and its network (BLN -> MD, abstract) | |
FAM.FT.SEP.MED | Medial Septal Nucleus | modulatory-ach | Thalamocortical relationships (s1MD -> MD, abstract) | |
FEC | FEC.FT.GPI.RM | Globus Pallidus Internal Rostromedial | inhibitory-gaba | Saccadic Vision (BG -> Thalamus, abstract) |
FMM | FMM.NC.PH.LEC | Lateral Entorhinal Cortex | excitatory-glu | Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract) |
FMM.NC.PH.PER | Perirhinal Cortex | excitatory-glu | Contributions of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract) | |
NCP | NCP.NC.MPL.PSCG | Posterior Cingulate Cortex | excitatory-glu | Contributions of Diencephalon to Recognition Memory (PostCingulate -> MDmc, abstract) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Reference |
NDM | NDM.NC.AL.DLPFCR | Rostral Mid-Dorsolateral Prefrontal Cortex | excitatory-glu | Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract) |
NDM.NC.AL.FPC | Lateral Frontopolar Cortex | excitatory-glu | Amygdala and its network (MD -> MPFC, abstract) |
Thirdparty Circuits
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map: ACG=Anterior Cingulate Cortex,NC.AL.ACG (Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG)), AM=Amygdala,FAM.FT.AM, HCA=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), HT=Hypothalamus,FD.HT, LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), OPFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PCA=Medial Parietal Lobule,NC.MPL, PN=Pontine Nuclear Complex,HT.PN (Principal Trigeminal Nucleus (LPC.HT.PN.PTR), Pontobulbar Body (LLC.HT.PN.PBB), Rostral Pontine Nucleus (LLC.HT.PN.RSP), Nuclei of Lateral Lemniscus (LPC.HT.PN.LL)), TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM), Central Mediodorsal Nucleus of Thalamus (NCP.FD.TH.MDC), Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL))
map: BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP, CEA=Central Amygdala,FAM.FT.AM.CEA (Central Amygdaloid Nucleus, capsular subdivision (FAM.FT.AM.CEC), Central Amygdaloid Nucleus, lateral subdivision (FAM.FT.AM.CEL), Medial Central Amygdaloid Nucleus (FAM.FT.AM.CEM)), EC=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC)), HC=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, ITC=Inferotemporal Cortex,NSA.NC.IT.TE, LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (Dorsolateral Amygdaloid Nucleus (FAM.FT.AM.LADL), Ventrolateral Amygdaloid Nucleus (FAM.FT.AM.LAVL), Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM)), LHB=Lateral Habenula,FAM.FD.LHB (Lateral Habenula Medial Part (FAM.FD.LHB.MED), Lateral Habenula Lateral Part (FAM.FD.LHB.LT)), MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM), Central Mediodorsal Nucleus of Thalamus (NCP.FD.TH.MDC), Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL)), MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC, NACC=Accumbens Nucleus,FEC.FT.ACC (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH)), PAG=Periaqueductal Gray Matter,LMC.MM.PAG, RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG, STC=Wernicke's area A3,NSA.NC.STG.A3, VGDM=Vagus Nucleus,LAC.HL.VGN, VTA=Ventral Tegmental Area,LMC.MM.VTA
map: ACG=Anterior Cingulate Cortex,NC.AL.ACG (Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG)), AM=Amygdala,FAM.FT.AM, HC=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN), Supramammillary Nucleus (LAC.FD.HT.SUM), Tuberomammillary Nucleus (LAC.FD.HT.TBM), Premammillary Nucleus (LAC.FD.HT.PRM)), HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV, INS=Insular Cortex,NC.INS, LC=Locus Coeruleus,LMC.HT.LC, MPFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PAG=Periaqueductal Gray Matter,LMC.MM.PAG, PB=Parabrachial Nucleus,LPC.HT.PRF.PB, PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE, SOL=Solitary Nucleus,LPC.HL.SOL, TH=Thalamus,FD.TH (Lateral Geniculate Nucleus (NSA.FD.LGN), Medial Geniculate Body (NSA.FD.TH.MGB), Ventral Posteroinferior Nucleus (NCP.FD.TH.VPI), Ventral Posterolateral Nucleus (NCP.FD.TH.VPL), Ventral Posteromedial Nucleus (NCP.FD.TH.VPM), Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV), Limitans Nucleus of Thalamus (NCP.FD.TH.LI), Suprageniculate Nucleus of Thalamus (NSA.FD.TH.SG), Submedial Nucleus of Thalamus (NDM.FD.TH.SM), Ventral Anterior Nucleus (NMA.FD.TH.VA), Ventral Lateral Nucleus (NMA.FD.TH.VL), Lateral Dorsal Nucleus of Thalamus (FMM.FD.TH.LD), Lateral Posterior Nucleus of Thalamus (NPE.FD.TH.LP), Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM), Central Mediodorsal Nucleus of Thalamus (NCP.FD.TH.MDC), Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL), Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD), Rostral Intralaminar Nuclear Group of Thalamus (NCP.FD.TH.RIL), Centromedian Nucleus of Thalamus (FEC.FD.TH.CM), Parafascicular Nucleus of Thalamus (FEC.FD.TH.PF), Paratenial Nucleus of Thalamus (FAM.FD.TH.PT), Paraventricular Nucleus of Thalamus (NDM.FD.TH.PV), Reuniens Nucleus of Thalamus (FMM.FD.TH.RE), Rhomboidal Nucleus of Thalamus (FMM.FD.TH.RH), Subfascicular Nucleus of Thalamus (LLC.FD.TH.SF))
References
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