Difference between revisions of "BrainRegionLAC FD HT LTN"

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* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Lateral Hypothalamic Area (LAC.FD.HT.LT) -> [[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus]] (LAC.FD.HT.LTN) (see [[OverallMindMaps|Mind Maps]])
 
* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Lateral Hypothalamic Area (LAC.FD.HT.LT) -> [[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus]] (LAC.FD.HT.LTN) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': nucleus
 
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]]
+
* '''Quality''': L0
 +
* '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]] (LAC)
 +
* '''Area circuit''': Thirst and Hunger Control (LATH)
 
* '''Role''': processor.autonomic
 
* '''Role''': processor.autonomic
 
* '''Function''': feeding center
 
* '''Function''': feeding center
* '''Notes to function''': lesions - lack of appetite
+
* '''Notes to function''':  
 +
** lesions - lack of appetite
 
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= Components =
 
= Components =
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> HTS)]
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || uncertain ||[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> HTS)]
 
|-
 
|-
|  || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)]
+
|  || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || uncertain ||[http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)]
 
|-
 
|-
|  || [[BrainRegionFAM_FT_SEP_SH|FAM.FT.SEP.SH]] || Septohippocampal Nucleus || excitatory-glu || [http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)]
+
|  || [[BrainRegionFAM_FT_SEP_SH|FAM.FT.SEP.SH]] || Septohippocampal Nucleus || excitatory-glu || uncertain ||[http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)]
 
|-
 
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || inhibitory-gaba || (unknown reference)
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || inhibitory-gaba || uncertain ||(unknown reference)
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_AR|LAC.FD.HT.AR]] || Arcuate Nucleus of Hypothalamus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_AR|LAC.FD.HT.AR]] || Arcuate Nucleus of Hypothalamus || excitatory-glu || uncertain ||[http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)]
 
|-
 
|-
|  || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> LHA)]
+
|  || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> LHA)]
 
|-
 
|-
|  || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || [http://ajpregu.physiology.org/content/302/2/R215 Glucose-sensing neural network (VMH -> LHA)]
+
|  || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://ajpregu.physiology.org/content/302/2/R215 Glucose-sensing neural network (VMH -> LHA)]
 
|-
 
|-
| [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || [http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (NTS -> LHA)]
+
| [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || uncertain ||[http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (NTS -> LHA)]
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
+
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || excitatory-glu || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)]
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || excitatory-glu || uncertain || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)]
 
|-
 
|-
|  || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)]
+
|  || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || uncertain || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)]
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || [http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (LHA -> PVN)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || uncertain || [http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (LHA -> PVN)]
 
|-
 
|-
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || Raphe Magnus Nucleus || excitatory-glu || (unknown reference)
+
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || Raphe Magnus Nucleus || excitatory-glu || uncertain || (unknown reference)
 
|-
 
|-
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_ROFCS|NDM.NC.AL.ROFCS]] || Sulcal Rostral Orbitofrontal Cortex || excitatory-glu || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract)]
+
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_ROFCS|NDM.NC.AL.ROFCS]] || Sulcal Rostral Orbitofrontal Cortex || excitatory-glu || uncertain || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract)]
 
|}
 
|}
  

Latest revision as of 18:27, 28 April 2019

Lateral Hypothalamic Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLAC -> BrainRegionLAC_FD_HT_LTN


This page covers biological details of component Lateral Hypothalamic Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Lateral Hypothalamic Area (LAC.FD.HT.LT) -> Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Autonomous Control Area (LAC)
  • Area circuit: Thirst and Hunger Control (LATH)
  • Role: processor.autonomic
  • Function: feeding center
  • Notes to function:
    • lesions - lack of appetite

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Components

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  • no child items defined

Connectivity

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LAC.FD.HT.LTN.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu uncertain Amygdala and its network (BLN -> HTS)
FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus excitatory-glu uncertain Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)
FAM.FT.SEP.SH Septohippocampal Nucleus excitatory-glu uncertain Cingulate Gyrus (SEP -> HT, abstract)
FEC FEC.FT.ACC.SH Nucleus Accumbens Shell inhibitory-gaba uncertain (unknown reference)
LAC LAC.FD.HT.AR Arcuate Nucleus of Hypothalamus excitatory-glu uncertain Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)
LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus excitatory-glu uncertain Eating and sleeping to survive (DMH -> LHA)
LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus excitatory-glu uncertain Glucose-sensing neural network (VMH -> LHA)
LPC LPC.HL.SOL Solitary Nucleus excitatory-glu uncertain Schematic of hypothalamic circuitry underlying satiety (NTS -> LHA)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FAM FAM.FD.LHB.LT Lateral Habenula Lateral Part excitatory-glu uncertain Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)
FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu uncertain Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)
LAC LAC.FD.HT.PV Paraventricular Nucleus excitatory-glu uncertain Schematic of hypothalamic circuitry underlying satiety (LHA -> PVN)
LMC LMC.HL.RP.MG Raphe Magnus Nucleus excitatory-glu uncertain (unknown reference)
NDM NDM.NC.AL.ROFCS Sulcal Rostral Orbitofrontal Cortex excitatory-glu uncertain Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract)

Thirdparty Circuits

(generated)

ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
NTS=Solitary Nucleus,LPC.HL.SOL
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

AMY=Amygdala,FAM.FT.AM
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia)
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ME=Endocrine Glands,TARGET.TEA.ENDOCRINE
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
NTS=Solitary Nucleus,LPC.HL.SOL
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
VTA=Ventral Tegmental Area,LMC.MM.VTA

DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DTG=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EPN=Endopiriform Nucleus,FAM.FT.EPF
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
LHT=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT
LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED
NI=Incertus Nucleus,FAM.HT.TG.NI
RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA
VTG=Ventral Tegmental Area,LMC.MM.VTG

DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT
LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
LS=Lateral Septal Nucleus,FAM.FT.SEP.LT
MHb=Medial Habenula,FAM.FD.MHB
MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
MS=Medial Septal Nucleus,FAM.FT.SEP.MED
PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei)
RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA

B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see Amygdala)
CE=Central Amygdala,FAM.FT.AM.CEA (see Amygdala)
Hippocampus=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
Hypothalamus=Hypothalamus,FD.HT
ITC=Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC
LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
vmPFC=Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC

ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
NTS=Solitary Nucleus,LPC.HL.SOL
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN

ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
PA=Paraventricular Nucleus,LAC.FD.HT.PV
SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
SON=Supraoptic Nucleus,LAC.FD.HT.SO
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
EP=Endopiriform Nucleus,FAM.FT.EPF
Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
L=Lateral Habenula,FAM.FD.LHB (see Habenula)
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
M=Medial Habenula,FAM.FD.MHB
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
Septum=Septal Nuclei,FAM.FT.SEP
VTA=Ventral Tegmental Area,LMC.MM.VTA

BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP
CEA=Central Amygdala,FAM.FT.AM.CEA (see Amygdala)
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ITC=Inferotemporal Cortex,NSA.NC.IT.TE
LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
LHB=Lateral Habenula,FAM.FD.LHB (see Habenula)
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
STC=Wernicke's area A3,NSA.NC.STG.A3
VGDM=Vagus Nucleus,LAC.HL.VGN
VTA=Ventral Tegmental Area,LMC.MM.VTA


References

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