BrainRegionNDM NC AL FPC
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Lateral Frontopolar Cortex
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This page covers biological details of component Lateral Frontopolar Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) -> Orbitofrontal Cortex (NC.AL.OPFC) -> Lateral Frontopolar Cortex (NDM.NC.AL.FPC) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Neocortical Brain - Decision Making Area
- Brodmann ID: 10
- Role: cortex.generic
- Function: Emotion Regulation
- Notes to function:
- Frontopolar area, contains ILC - infralimbic cortex
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Reference |
LMC | LMC.FT.NBM | Basal Nucleus of Meynert | modulatory-ach | Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract) |
LMC.MM.VTA | Ventral Tegmental Area | modulatory-da | Amygdala and its network (VTA -> MPFC, abstract) | |
NCP | NCP.NC.INS.PPC | Peripaleocortical Claustral | feedforward-glu | Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract) |
NDM | NDM.FD.TH.MDM | Medial Mediodorsal Nucleus of Thalamus | excitatory-glu | Amygdala and its network (MD -> MPFC, abstract) |
Outbound Region Connections:
Thirdparty Circuits
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- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Bowels control brain: gut hormones and obesity - see Reference (CP.BOWELS)
AMY=Amygdala,FAM.FT.AM ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia) LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ME=Endocrine Glands,TARGET.TEA.ENDOCRINE NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) NTS=Solitary Nucleus,LPC.HL.SOL OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM VTA=Ventral Tegmental Area,LMC.MM.VTA
- Thalamocortical relationships - see Reference (CL.THALAMUS-PROJECTIONS)
A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MGN=Medial Geniculate Body,NSA.FD.TH.MGB P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus) VA=Ventral Anterior Nucleus,NMA.FD.TH.VA VL=Ventral Lateral Nucleus,NMA.FD.TH.VL VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia) pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) pLGN=Primary Visual Cortex,NSA.NC.OCC.V1 pLP=Superior Parietal Lobule,NC.SPL pMD=Prefrontal Cortex,NC.AL.PFC pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1 pP=Insular Cortex,NC.INS pVA=Supplementary Motor Cortex,NMA.NC.SMC pVL=Motor Cortex,NMA.NC.MC pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1 pVPM=Precentral Cortex,NCP.NC.PO.PCC s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) s1MD=Septal Nuclei,FAM.FT.SEP s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV s1VL=Dentate Nucleus,LLC.HT.CR.DN s2A=Mammillary Body,FD.MB (see Hypothalamus) s2MD=Piriform Cortex,NSA.NC.PH.PIR s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR s2VL=Basal Ganglia,FEC.FT.BG s3MD=Prefrontal Cortex,NC.AL.PFC sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) sLD=Superior Parietal Lobule,NC.SPL sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) sVA=Basal Ganglia,FEC.FT.BG sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn) sVPM=Solitary Nucleus,LPC.HL.SOL
- Prefrontal Cortex (PFC) in emotional behavior - see Reference (CF.PFC-EMOTIONS)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AM=Amygdala,FAM.FT.AM HCA=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HT=Hypothalamus,FD.HT LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PCA=Medial Parietal Lobule,NC.MPL PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei) TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
- Role for serotonin in moral behavior - see Reference (CF.EMOTIONAL-MODULATION)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AMY=Amygdala,FAM.FT.AM HYP=Hypothalamus,FD.HT LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Amygdala and its network - see Reference (CF.AM-NET)
BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP CEA=Central Amygdala,FAM.FT.AM.CEA (see Amygdala) EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ITC=Inferotemporal Cortex,NSA.NC.IT.TE LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala) LHB=Lateral Habenula,FAM.FD.LHB (see Habenula) MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG STC=Wernicke's area A3,NSA.NC.STG.A3 VGDM=Vagus Nucleus,LAC.HL.VGN VTA=Ventral Tegmental Area,LMC.MM.VTA
- Affective basal ganglia circuit - see Reference (CF.AFFECTIVE-BG)
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) nBM=Basal Nucleus of Meynert,LMC.FT.NBM
References
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- http://www.sciencedirect.com/science/article/pii/S0959438808001566
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
- http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/
- https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
- http://www.pnas.org/content/107/40/17071/F1.expansion.html
- http://www.impulsecontroldisorders.org/html/cravings.html
- http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
- http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx