BrainRegionNMA NC PMC F2

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Dorsal Caudal Premotor Cortex

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This page covers biological details of component Dorsal Caudal Premotor Cortex. Region is part of aHuman target integrated biological model.

Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Premotor Cortex (NC.PMC) -> Dorsal Premotor Cortex (MCA.NC.DPMC) -> Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2) (see Mind Maps)
Type: cortex
Brain area: Neocortical Brain - Motor Aggregation Area
Brodmann ID: 06
Role: cortex.motor.extensor
Function: Guiding reaching
Notes to function: 6DC; Active during preparation for reach and also during reach itself; leg and arm; transform sensory information into motor representation; preparation and execution of motor acts

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Contents

1 Components
2 Connectivity
3 Thirdparty Circuits
4 References

Components

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no child items defined

Connectivity

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NMA.NC.PMC.F2.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NCP	NCP.NC.PG.S1	Primary Somatosensory Cortex	feedforward-glu	Global visual system (ParietalCortex -> FrontalCortex, abstract)
	NCP.NC.SPL.SA	Somatosensory Association Cortex	feedforward-glu	3 Visual Cortex Paths (SPL -> dPM, abstract)
NDM	NDM.NC.AL.VACG	Ventral Anterior Cingulate Area	feedforward-glu	(unknown reference)
NMA	NMA.FD.TH.VA	Ventral Anterior Nucleus	excitatory-glu	Prefrontal Cortex (PFC) in motor behavior (TH -> PMC, abstract)
	NMA.NC.PMC.F4	Ventral Caudal Premotor Cortex	feedforward-glu	(unknown reference)
	NMA.NC.PMC.F5	Ventral Rostral Premotor Cortex	feedforward-glu	(unknown reference)
	NMA.NC.PMC.F7	Dorsal Rostral Premotor Cortex	feedforward-glu	(unknown reference)
	NMA.NC.SMC.F3	Supplementary Motor Area	feedforward-glu	3 Visual Cortex Paths (pre-SMA -> dPM, abstract)
NPE	NPE.NC.IPL.SMW	Supramarginal Wernike Cortex	feedforward-glu	Dual Auditory Processing (PPC -> DLPFC, abstract)
	NPE.NC.SPL.PF	Rostral Precuneus	feedforward-glu	3 Visual Cortex Paths (SPL -> dPM, abstract)
	NPE.NC.SPL.PG	Caudal Precuneus	feedforward-glu	3 Visual Cortex Paths (SPL -> dPM, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.PU.MED	Dorsal Putamen Medial	excitatory-glu	Global visual system (FrontalCortex -> BGA, abstract)
NMA	NMA.NC.MC	Motor Cortex	feedforward-glu	Prefrontal Cortex (PFC) in motor behavior (PMC -> MC, abstract)

Thirdparty Circuits

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Global visual system - see Reference

map: ATH=Anterior Nucleus of Thalamus,FD.TH.AN (Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD)), BGA=Basal Ganglia,FEC.FT.BG, FrontalCortex=Anterior Lobe,NC.LOBE.ANT (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC), Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG), Ventral Medial Cingulate Area (NDM.NC.AL.VMCG), Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG), Pregenual Cingulate Cortex (NDM.NC.AL.PGCG), Motor Cortex (NMA.NC.MC), Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF), Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7), Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5), Supplementary Eye Field (NPE.NC.SMC.SEF), Pre-Supplementary Motor Area (NMA.NC.SMC.F6), Supplementary Motor Area (NMA.NC.SMC.F3)), LGN=Lateral Geniculate Nucleus,NSA.FD.LGN, OPN=Oculomotor Nucleus,LPC.MM.OCN, ParietalCortex=Parietal Lobe,NC.LOBE.PAR (Medial Superior Temporal Area (NPE.NC.IPL.MST), Supramarginal Wernike Cortex (NPE.NC.IPL.SMW), Retrosplenial Cortex (NCP.NC.MPL.RSC), Posterior Cingulate Cortex (NCP.NC.MPL.PSCG), Subgenual Cingulate Cortex (NCP.NC.MPL.SGCG), Precentral Cortex (NCP.NC.PO.PCC), Primary Somatosensory Cortex (NCP.NC.PG.S1), Secondary Somatosensory Cortex (NCP.NC.PG.S2), Parietal Ventral Cortex (NCP.NC.PG.PV), Somatosensory Association Cortex (NCP.NC.SPL.SA), Rostral Precuneus (NPE.NC.SPL.PF), Caudal Precuneus (NPE.NC.SPL.PG), Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP), Ventral Intraparietal Sulcus (NSA.NC.IPS.VIP), Anterior Intraparietal Sulcus (NSA.NC.IPS.AIP)), Pulvinar=Pulvinar,FD.PV (Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV)), RF=Pontine Reticular Formation,HT.RF, Retina=Retinal Nucleus,LPC.FD.RT, SCi=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SCs=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT, SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL, SpinalCord=Lamina IX,SC.VH.L9 (Ventrolateral Nucleus (LPC.SC.VH.VL), Posterolateral Nucleus (LPC.SC.VH.PL), Retroposterolateral Nucleus (LPC.SC.VH.RPL), Spinal Accessory Nucleus (LPC.SC.VH.SAN), Phrenic Nucleus (LPC.SC.VH.PHR), Onuf's Nucleus (LPC.SC.VH.ONF)), Striatum=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), VisualCortex=Occipital Lobe,NC.LOBE.OCC unavailable

Prefrontal Cortex (PFC) in motor behavior - see Reference

map: CN.PU=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), CR=Cerebellar Complex,LLC.HT.CRC, GP=Globus Pallidus,FEC.FT.GP (Globus Pallidus External Lateral (FEC.FT.GPE.LT), Globus Pallidus External Medial (FEC.FT.GPE.MED), Globus Pallidus External Dorsal (FEC.FT.GPE.DS), Globus Pallidus External Rostromedial (FEC.FT.GPE.RM), Globus Pallidus External Dorsolateral (FEC.FT.GPE.DL), Globus Pallidus Internal Lateral (FEC.FT.GPI.LT), Globus Pallidus Internal Medial (FEC.FT.GPI.MED), Globus Pallidus Internal Dorsal (FEC.FT.GPI.DS), Globus Pallidus Internal Rostromedial (FEC.FT.GPI.RM), Globus Pallidus Internal Dorsolateral (FEC.FT.GPI.DL), Ventral Pallidum Dorsolateral (FEC.FT.VP.DL), Ventral Pallidum Ventromedial (FEC.FT.VP.VM)), LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), MC=Motor Cortex,NMA.NC.MC, PMC=Premotor Cortex,NC.PMC, PN=Pontine Nuclear Complex,HT.PN (Principal Trigeminal Nucleus (LPC.HT.PN.PTR), Pontobulbar Body (LLC.HT.PN.PBB), Rostral Pontine Nucleus (LLC.HT.PN.RSP), Nuclei of Lateral Lemniscus (LPC.HT.PN.LL)), SN=Substantia Nigra,FEC.FT.SN (Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT), Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED), Substantia Nigra Pars Reticulata Dorsolateral (FEC.FT.SNR.DL), Substantia Nigra Pars Reticulata Rostromedial (FEC.FT.SNR.RM), Substantia Nigra Pars Reticulata Ventrolateral (FEC.FT.SNR.VL), Substantia Nigra Pars Reticulata Medial (FEC.FT.SNR.MED)), TH=Ventral Thalamus,FD.TH.VTH (Ventral Anterior Nucleus (NMA.FD.TH.VA), Ventral Lateral Nucleus (NMA.FD.TH.VL)) unavailable

Cortico-Cortical Connectivity - see Reference

map: A1=Primary Auditory Cortex,NSA.NC.TTG.A1, AA=Wernicke's area A3,NSA.NC.STG.A3, M1=Motor Cortex,NMA.NC.MC, MA=Premotor Cortex,NC.PMC, PFC=Prefrontal Cortex,NC.AL.PFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC)), PTHA=Inferior Parietal Lobule,NC.IPL, S1=Primary Somatosensory Cortex,NCP.NC.PG.S1, SA=Somatosensory Association Cortex,NCP.NC.SPL.SA, V1=Primary Visual Cortex,NSA.NC.OCC.V1, VA=Secondary Visual Cortex,NSA.NC.OCC.V2 (Secondary Visual Cortex, Thin Stripe (NSA.NC.OCC.V2TN), Secondary Visual Cortex, Thick Stripe (NSA.NC.OCC.V2TK), Secondary Visual Cortex, Pale Stripe (NPE.NC.OCC.V2PL)) unavailable

Primate Control of Grasping - see Reference

map: 46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), AIP=Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP, BG=Basal Ganglia,FEC.FT.BG, BTH=Ventral Anterior Nucleus,NMA.FD.TH.VA, F1=Motor Cortex,NMA.NC.MC, F2=Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2, F4=Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4, F5=Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5, F6=Pre-Supplementary Motor Area,NMA.NC.SMC.F6, IT=Inferotemporal Area,NSA.NC.IT, PIP=Posterior Eye Field,NPE.NC.IPS.PEF (Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP)), S1=Primary Somatosensory Cortex,NCP.NC.PG.S1, S2=Primary Somatosensory Cortex,NCP.NC.PG.S1, VC=Occipital Lobe,NC.LOBE.OCC, VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP unavailable

References

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