BrainRegionNMA NC SMC F3

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Supplementary Motor Area

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This page covers biological details of component Supplementary Motor Area. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Supplementary Motor Cortex (NMA.NC.SMC) -> Supplementary Motor Area (NMA.NC.SMC.F3) (see Mind Maps)
  • Type: cortex
  • Brain area: Neocortical Brain - Motor Aggregation Area
  • Brodmann ID: 06
  • Role: cortex.generic
  • Function: Movement execution; Numerical and verbal mental-operation tasks
  • Notes to function: from TH/VLo from from putamen; F1/F2/F4/24d - strong; F6/F7/F5/24c - modest; no input from the prefrontal lobe

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Components

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  • no child items defined

Connectivity

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NMA.NC.SMC.F3.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
NMA NMA.FD.TH.VA Ventral Anterior Nucleus excitatory-glu Thalamocortical relationships (VA -> pVA, abstract)
NMA.NC.PMC.F4 Ventral Caudal Premotor Cortex feedforward-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FEC FEC.FT.PU.MED Dorsal Putamen Medial excitatory-glu Global visual system (FrontalCortex -> BGA, abstract)
LLC LLC.HT.PRF.RTMG Pontine Reticulotegmental Nucleus excitatory-glu Motor neurons control (CTX -> PRF, abstract)
LRC LRC.HL.PRF.GCR Gigantocellular Reticular Nucleus excitatory-glu Motor neurons control (CTX -> MRF, abstract)
LRC.HT.PRF.CRF Caudal Pontine Reticular Nucleus excitatory-glu Motor neurons control (CTX -> PRF, abstract)
NMA NMA.NC.PMC.F2 Dorsal Caudal Premotor Cortex feedforward-glu 3 Visual Cortex Paths (pre-SMA -> dPM, abstract)
NMA.NC.PMC.F5 Ventral Rostral Premotor Cortex feedforward-glu 3 Visual Cortex Paths (pre-SMA -> vPM, abstract)

Thirdparty Circuits

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map: ATH=Anterior Nucleus of Thalamus,FD.TH.AN (Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD)), BGA=Basal Ganglia,FEC.FT.BG, FrontalCortex=Anterior Lobe,NC.LOBE.ANT (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC), Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG), Ventral Medial Cingulate Area (NDM.NC.AL.VMCG), Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG), Pregenual Cingulate Cortex (NDM.NC.AL.PGCG), Motor Cortex (NMA.NC.MC), Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF), Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7), Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5), Supplementary Eye Field (NPE.NC.SMC.SEF), Pre-Supplementary Motor Area (NMA.NC.SMC.F6), Supplementary Motor Area (NMA.NC.SMC.F3)), LGN=Lateral Geniculate Nucleus,NSA.FD.LGN, OPN=Oculomotor Nucleus,LPC.MM.OCN, ParietalCortex=Parietal Lobe,NC.LOBE.PAR (Medial Superior Temporal Area (NPE.NC.IPL.MST), Supramarginal Wernike Cortex (NPE.NC.IPL.SMW), Retrosplenial Cortex (NCP.NC.MPL.RSC), Posterior Cingulate Cortex (NCP.NC.MPL.PSCG), Subgenual Cingulate Cortex (NCP.NC.MPL.SGCG), Precentral Cortex (NCP.NC.PO.PCC), Primary Somatosensory Cortex (NCP.NC.PG.S1), Secondary Somatosensory Cortex (NCP.NC.PG.S2), Parietal Ventral Cortex (NCP.NC.PG.PV), Somatosensory Association Cortex (NCP.NC.SPL.SA), Rostral Precuneus (NPE.NC.SPL.PF), Caudal Precuneus (NPE.NC.SPL.PG), Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP), Ventral Intraparietal Sulcus (NSA.NC.IPS.VIP), Anterior Intraparietal Sulcus (NSA.NC.IPS.AIP)), Pulvinar=Pulvinar,FD.PV (Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV)), RF=Pontine Reticular Formation,HT.RF, Retina=Retinal Nucleus,LPC.FD.RT, SCi=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SCs=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT, SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL, SpinalCord=Lamina IX,SC.VH.L9 (Ventrolateral Nucleus (LPC.SC.VH.VL), Posterolateral Nucleus (LPC.SC.VH.PL), Retroposterolateral Nucleus (LPC.SC.VH.RPL), Spinal Accessory Nucleus (LPC.SC.VH.SAN), Phrenic Nucleus (LPC.SC.VH.PHR), Onuf's Nucleus (LPC.SC.VH.ONF)), Striatum=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), VisualCortex=Occipital Lobe,NC.LOBE.OCC unavailable

map: IPL=Inferior Parietal Lobule,NC.IPL, IPS=Intraparietal Sulcus,NSA.NC.IPS, IT=Inferotemporal Area,NSA.NC.IT, LPC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), MI=Motor Cortex,NMA.NC.MC, OCC=Occipital Lobe,NC.LOBE.OCC, SPL=Superior Parietal Lobule,NC.SPL, dPM=Dorsal Premotor Cortex,MCA.NC.DPMC (Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7)), pre-SMA=Supplementary Motor Cortex,NMA.NC.SMC, vPM=Ventral Premotor Cortex,MCA.NC.VPMC (Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5)) unavailable

map: CR=Cerebellum,LLC.HT.CR (Cerebellar Flocconodular Lobe (LRC.HT.CR.FN), Cerebellar Lateral Lobe (LLC.HT.CR.CC), Cerebellar Paravermis (LLC.HT.CR.PV), Cerebellar Vermis (LRC.HT.CR.VM)), CTX=Anterior Lobe,NC.LOBE.ANT (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC), Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG), Ventral Medial Cingulate Area (NDM.NC.AL.VMCG), Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG), Pregenual Cingulate Cortex (NDM.NC.AL.PGCG), Motor Cortex (NMA.NC.MC), Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF), Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7), Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5), Supplementary Eye Field (NPE.NC.SMC.SEF), Pre-Supplementary Motor Area (NMA.NC.SMC.F6), Supplementary Motor Area (NMA.NC.SMC.F3)), EAMN=Anterior/Ventral Horn,SC.VH, EGMN=Anterior/Ventral Horn,SC.VH, FAMN=Anterior/Ventral Horn,SC.VH, FG=Fastigual Nucleus,LRC.HT.CR.FG, IP=Interposed Nucleus,LLC.HT.CR.IP (Emboliform Nucleus (LLC.HT.CR.EN), Globose Nucleus (LLC.HT.CR.GN)), LT=Dentate Nucleus,LLC.HT.CR.DN, MRF=Medullary Reticular Formation,HL.RF, PRF=Pontine Reticular Formation,HT.RF, RD=Red Nucleus,LLC.MM.RD, VB=Vestibular Nuclei,LPC.HT.VBN unavailable


References

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