BrainRegionLRC HT PRF RPO

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Oral Pontine Reticular Nucleus

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This page covers biological details of component Oral Pontine Reticular Nucleus. Region is part of aHuman target integrated biological model.

Top-down path to region: Hindbrain Metencephalon -> Pontine Reticular Formation (HT.RF) -> Pontine Reticular Formation, Medial Column (HT.RF.MED) -> Paramedian Pontine Reticular Formation (HT.PRF.PPRF) -> Oral Pontine Reticular Nucleus (LRC.HT.PRF.RPO) (see Mind Maps)
Type: nucleus
Brain area: Lower Brain - Motor Reflex Area
Role: subcortical.motor.flexor
Function: Mediation of changing to and from REM sleep
Notes to function: Part of horizontal gaze center, projects to spinal cord and abducens; excites spinal extensors, inhibit flexors

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Contents

1 Components
2 Connectivity
3 Thirdparty Circuits
4 References

Components

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no child items defined

Connectivity

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LRC.HT.PRF.RPO.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LRC	LRC.MM.RP.RIP	Raphe Interpositus Nucleus	excitatory-glu	Horizontal saccades and smooth pursuit movements (RIP -> PPRF, abstract)
	LRC.MM.SC.DEEP	Deep Superior Colliculus	excitatory-glu	Summary of eye movement control (SC -> PPRF, abstract)
NPE	NPE.NC.BRA.PO	Broca's Area Pars Opercularis	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
	NPE.NC.PMC.AFEF	Anterior Frontal Eye Field	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
NSA	NSA.NC.IT.TE	Inferotemporal Cortex	excitatory-glu	Saccades and smooth movements (TEF -> DLPN, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.HT.TG.NI	Incertus Nucleus	excitatory-glu	(unknown reference)
LLC	LLC.HT.CR.CC	Cerebellar Lateral Lobe	excitatory-glu	Saccades and smooth movements (DLPN -> CR, abstract)
LPC	LPC.HT.ABD	Abducens Nucleus	excitatory-glu	Vestibulo-ocular reflex (VOR) (PPRF -> Abducens, abstract)
	LPC.HT.IVBN	Inferior Vestibular Nuclei	excitatory-glu	(unknown reference)
	LPC.MM.OCN	Oculomotor Nucleus	excitatory-glu	Global visual system (RF -> OPN, abstract)
	LPC.SC.VH.SAN	Spinal Accessory Nucleus	excitatory-glu	Cerebellum functional divisions (RF -> SCM, abstract)
	LPC.SC.VH.VL	Ventrolateral Nucleus	excitatory-glu	Cerebellum functional divisions (RF -> SCM, abstract)
	LPC.SC.VH.VM	Ventromedial Nucleus	excitatory-glu	Cerebellum functional divisions (RF -> SCM, abstract)

Thirdparty Circuits

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Vestibulo-ocular reflex (VOR) - see Reference

map: Abducens=Abducens Nucleus,LPC.HT.ABD, FEF=Frontal Eye Field,NMA.NC.PMC.FEF (Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF)), Oculomotor=Oculomotor Nucleus,LPC.MM.OCN, PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (Oral Pontine Reticular Nucleus (LRC.HT.PRF.RPO), Caudal Pontine Reticular Nucleus (LRC.HT.PRF.CRF), Parvocellular Reticular Nucleus (LRC.HT.PRF.PVR)), VestibularGanglion=Vestibular Ganglion,LPC.PN.SG.VB, VestibularNuclei=Inferior Vestibular Nuclei,LPC.HT.IVBN unavailable

Saccades and smooth movements (unknown reference)

map: CN=Caudate Nucleus,FEC.FT.CN (Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL)), CR=Cerebellum,LLC.HT.CR (Cerebellar Flocconodular Lobe (LRC.HT.CR.FN), Cerebellar Lateral Lobe (LLC.HT.CR.CC), Cerebellar Paravermis (LLC.HT.CR.PV), Cerebellar Vermis (LRC.HT.CR.VM)), DLPN=Oral Pontine Reticular Nucleus,LRC.HT.PRF.RPO, Extrastriate=Associative Visual Cortex,NPE.NC.OCC.V3 (Dorsal Associative Visual Cortex (NPE.NC.OCC.V3D), Ventral Associative Visual Cortex (NPE.NC.OCC.V3V)), FEF=Frontal Eye Field,NMA.NC.PMC.FEF (Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF)), PPC=Posterior Eye Field,NPE.NC.IPS.PEF (Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP)), PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (Oral Pontine Reticular Nucleus (LRC.HT.PRF.RPO), Caudal Pontine Reticular Nucleus (LRC.HT.PRF.CRF), Parvocellular Reticular Nucleus (LRC.HT.PRF.PVR)), SC=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SN=Substantia Nigra,FEC.FT.SN (Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT), Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED), Substantia Nigra Pars Reticulata Dorsolateral (FEC.FT.SNR.DL), Substantia Nigra Pars Reticulata Rostromedial (FEC.FT.SNR.RM), Substantia Nigra Pars Reticulata Ventrolateral (FEC.FT.SNR.VL), Substantia Nigra Pars Reticulata Medial (FEC.FT.SNR.MED)), Striate=Primary Visual Cortex,NSA.NC.OCC.V1, TEF=Inferotemporal Area,NSA.NC.IT, VGC=Cajal Nucleus,LRC.MM.CJ, Vestibular=Lateral Vestibular Nucleus,LPC.HT.LVBN unavailable

Global visual system - see Reference

map: ATH=Anterior Nucleus of Thalamus,FD.TH.AN (Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD)), BGA=Basal Ganglia,FEC.FT.BG, FrontalCortex=Anterior Lobe,NC.LOBE.ANT (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC), Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG), Ventral Medial Cingulate Area (NDM.NC.AL.VMCG), Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG), Pregenual Cingulate Cortex (NDM.NC.AL.PGCG), Motor Cortex (NMA.NC.MC), Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF), Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7), Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5), Supplementary Eye Field (NPE.NC.SMC.SEF), Pre-Supplementary Motor Area (NMA.NC.SMC.F6), Supplementary Motor Area (NMA.NC.SMC.F3)), LGN=Lateral Geniculate Nucleus,NSA.FD.LGN, OPN=Oculomotor Nucleus,LPC.MM.OCN, ParietalCortex=Parietal Lobe,NC.LOBE.PAR (Medial Superior Temporal Area (NPE.NC.IPL.MST), Supramarginal Wernike Cortex (NPE.NC.IPL.SMW), Retrosplenial Cortex (NCP.NC.MPL.RSC), Posterior Cingulate Cortex (NCP.NC.MPL.PSCG), Subgenual Cingulate Cortex (NCP.NC.MPL.SGCG), Precentral Cortex (NCP.NC.PO.PCC), Primary Somatosensory Cortex (NCP.NC.PG.S1), Secondary Somatosensory Cortex (NCP.NC.PG.S2), Parietal Ventral Cortex (NCP.NC.PG.PV), Somatosensory Association Cortex (NCP.NC.SPL.SA), Rostral Precuneus (NPE.NC.SPL.PF), Caudal Precuneus (NPE.NC.SPL.PG), Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP), Ventral Intraparietal Sulcus (NSA.NC.IPS.VIP), Anterior Intraparietal Sulcus (NSA.NC.IPS.AIP)), Pulvinar=Pulvinar,FD.PV (Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV)), RF=Pontine Reticular Formation,HT.RF, Retina=Retinal Nucleus,LPC.FD.RT, SCi=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SCs=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT, SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL, SpinalCord=Lamina IX,SC.VH.L9 (Ventrolateral Nucleus (LPC.SC.VH.VL), Posterolateral Nucleus (LPC.SC.VH.PL), Retroposterolateral Nucleus (LPC.SC.VH.RPL), Spinal Accessory Nucleus (LPC.SC.VH.SAN), Phrenic Nucleus (LPC.SC.VH.PHR), Onuf's Nucleus (LPC.SC.VH.ONF)), Striatum=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), VisualCortex=Occipital Lobe,NC.LOBE.OCC unavailable

Cerebellum functional divisions - see Reference

map: CCV=Central Cervical Nucleus,LPC.SC.IZ.CCV, CRP=Cerebellar Lateral Lobe,LLC.HT.CR.CC, CRS=Cerebellar Paravermis,LLC.HT.CR.PV, CRV=Cerebellar Vermis,LRC.HT.CR.VM, CTX=Anterior Lobe,NC.LOBE.ANT (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC), Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG), Ventral Medial Cingulate Area (NDM.NC.AL.VMCG), Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG), Pregenual Cingulate Cortex (NDM.NC.AL.PGCG), Motor Cortex (NMA.NC.MC), Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF), Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7), Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5), Supplementary Eye Field (NPE.NC.SMC.SEF), Pre-Supplementary Motor Area (NMA.NC.SMC.F6), Supplementary Motor Area (NMA.NC.SMC.F3)), DN=Dentate Nucleus,LLC.HT.CR.DN, FG=Fastigual Nucleus,LRC.HT.CR.FG, IO=Inferior Olivary Nucleus,LLC.HL.IO, IP=Interposed Nucleus,LLC.HT.CR.IP (Emboliform Nucleus (LLC.HT.CR.EN), Globose Nucleus (LLC.HT.CR.GN)), LT=Dentate Nucleus,LLC.HT.CR.DN, PNN=Basilar Pontine Nuclei,LLC.HT.BPN, RD=Red Nucleus,LLC.MM.RD, RF=Pontine Reticular Formation,HT.RF, SCM=Anterior/Ventral Horn,SC.VH, SCS=Proprius Nucleus,LPC.SC.PH.NP, SCSD=Clarke Nucleus,LPC.SC.PH.CL, VB=Vestibular Nuclei,LPC.HT.VBN, VBG=Vestibular Ganglion,LPC.PN.SG.VB, VL=Ventral Lateral Nucleus,NMA.FD.TH.VL unavailable

References

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