BrainRegionFEC FT GPI RM

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Globus Pallidus Internal Rostromedial

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This page covers biological details of component Globus Pallidus Internal Rostromedial. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Globus Pallidus (FEC.FT.GP) -> Dorsal Pallidum (FEC.FT.DP) -> Globus Pallidus Internal (FEC.FT.GPI) -> Globus Pallidus Internal Rostromedial (FEC.FT.GPI.RM) (see Mind Maps)
  • Type: nucleus
  • Brain area: Forebrain - Execution Control Area
  • Role: basal.ganglia.suppress
  • Function: Motivational loop

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Components

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  • no child items defined

Connectivity

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FEC.FT.GPI.RM.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FEC FEC.FD.STN.DL Subthalamic Nucleus Dorsolateral excitatory-glu Basal Ganglia Activity (STN -> GPi, abstract)
FEC.FT.CN.TL Caudate Nucleus Tail inhibitory-gaba Habenula Connections (CPu -> GPi, abstract)
FEC.FT.GPE.RM Globus Pallidus External Rostromedial inhibitory-gaba (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FEC FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial inhibitory-gaba Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)
NDM NDM.FD.TH.MDM Medial Mediodorsal Nucleus of Thalamus inhibitory-gaba Saccadic Vision (BG -> Thalamus, abstract)

Thirdparty Circuits

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map: BG=Basal Ganglia,FEC.FT.BG, CN=Caudate Nucleus,FEC.FT.CN (Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL)), CR=Cerebellum,LLC.HT.CR (Cerebellar Flocconodular Lobe (LRC.HT.CR.FN), Cerebellar Lateral Lobe (LLC.HT.CR.CC), Cerebellar Paravermis (LLC.HT.CR.PV), Cerebellar Vermis (LRC.HT.CR.VM)), FrontalCortex=Anterior Lobe,NC.LOBE.ANT (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC), Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG), Ventral Medial Cingulate Area (NDM.NC.AL.VMCG), Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG), Pregenual Cingulate Cortex (NDM.NC.AL.PGCG), Motor Cortex (NMA.NC.MC), Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF), Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7), Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5), Supplementary Eye Field (NPE.NC.SMC.SEF), Pre-Supplementary Motor Area (NMA.NC.SMC.F6), Supplementary Motor Area (NMA.NC.SMC.F3)), GPe=Globus Pallidus External,FEC.FT.GPE (Globus Pallidus External Lateral (FEC.FT.GPE.LT), Globus Pallidus External Medial (FEC.FT.GPE.MED), Globus Pallidus External Dorsal (FEC.FT.GPE.DS), Globus Pallidus External Rostromedial (FEC.FT.GPE.RM), Globus Pallidus External Dorsolateral (FEC.FT.GPE.DL)), LGN=Lateral Geniculate Nucleus,NSA.FD.LGN, LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP, RF=Pontine Reticular Formation,HT.RF, Retina=Retinal Nucleus,LPC.FD.RT, SCi=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SCs=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL, STN=Subthalamic Nucleus,FEC.FD.STN (Subthalamic Nucleus Caudal (FEC.FD.STN.CD), Subthalamic Nucleus Internal Caudal (FEC.FD.STN.ICD), Subthalamic Nucleus Dorsolateral (FEC.FD.STN.DL), Subthalamic Nucleus Lateral (FEC.FD.STN.LT), Subthalamic Nucleus Medial (FEC.FD.STN.MED)), Thalamus=Thalamus,FD.TH (Lateral Geniculate Nucleus (NSA.FD.LGN), Medial Geniculate Body (NSA.FD.TH.MGB), Ventral Posteroinferior Nucleus (NCP.FD.TH.VPI), Ventral Posterolateral Nucleus (NCP.FD.TH.VPL), Ventral Posteromedial Nucleus (NCP.FD.TH.VPM), Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV), Limitans Nucleus of Thalamus (NCP.FD.TH.LI), Suprageniculate Nucleus of Thalamus (NSA.FD.TH.SG), Submedial Nucleus of Thalamus (NDM.FD.TH.SM), Ventral Anterior Nucleus (NMA.FD.TH.VA), Ventral Lateral Nucleus (NMA.FD.TH.VL), Lateral Dorsal Nucleus of Thalamus (FMM.FD.TH.LD), Lateral Posterior Nucleus of Thalamus (NPE.FD.TH.LP), Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM), Central Mediodorsal Nucleus of Thalamus (NCP.FD.TH.MDC), Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL), Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD), Rostral Intralaminar Nuclear Group of Thalamus (NCP.FD.TH.RIL), Centromedian Nucleus of Thalamus (FEC.FD.TH.CM), Parafascicular Nucleus of Thalamus (FEC.FD.TH.PF), Paratenial Nucleus of Thalamus (FAM.FD.TH.PT), Paraventricular Nucleus of Thalamus (NDM.FD.TH.PV), Reuniens Nucleus of Thalamus (FMM.FD.TH.RE), Rhomboidal Nucleus of Thalamus (FMM.FD.TH.RH), Subfascicular Nucleus of Thalamus (LLC.FD.TH.SF)), VisualCortex=Occipital Lobe,NC.LOBE.OCC unavailable

map: CN.PU=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), CR=Cerebellar Complex,LLC.HT.CRC, GP=Globus Pallidus,FEC.FT.GP (Globus Pallidus External Lateral (FEC.FT.GPE.LT), Globus Pallidus External Medial (FEC.FT.GPE.MED), Globus Pallidus External Dorsal (FEC.FT.GPE.DS), Globus Pallidus External Rostromedial (FEC.FT.GPE.RM), Globus Pallidus External Dorsolateral (FEC.FT.GPE.DL), Globus Pallidus Internal Lateral (FEC.FT.GPI.LT), Globus Pallidus Internal Medial (FEC.FT.GPI.MED), Globus Pallidus Internal Dorsal (FEC.FT.GPI.DS), Globus Pallidus Internal Rostromedial (FEC.FT.GPI.RM), Globus Pallidus Internal Dorsolateral (FEC.FT.GPI.DL), Ventral Pallidum Dorsolateral (FEC.FT.VP.DL), Ventral Pallidum Ventromedial (FEC.FT.VP.VM)), LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), MC=Motor Cortex,NMA.NC.MC, PMC=Premotor Cortex,NC.PMC, PN=Pontine Nuclear Complex,HT.PN (Principal Trigeminal Nucleus (LPC.HT.PN.PTR), Pontobulbar Body (LLC.HT.PN.PBB), Rostral Pontine Nucleus (LLC.HT.PN.RSP), Nuclei of Lateral Lemniscus (LPC.HT.PN.LL)), SN=Substantia Nigra,FEC.FT.SN (Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT), Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED), Substantia Nigra Pars Reticulata Dorsolateral (FEC.FT.SNR.DL), Substantia Nigra Pars Reticulata Rostromedial (FEC.FT.SNR.RM), Substantia Nigra Pars Reticulata Ventrolateral (FEC.FT.SNR.VL), Substantia Nigra Pars Reticulata Medial (FEC.FT.SNR.MED)), TH=Ventral Thalamus,FD.TH.VTH (Ventral Anterior Nucleus (NMA.FD.TH.VA), Ventral Lateral Nucleus (NMA.FD.TH.VL)) unavailable


References

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