BrainAreaFEC
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Forebrain Execution Control Area
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Contents
Local Circuits
(generated)
| ID | Name | Regions |
| FECAF | Cognitive Motivational Salience | FEC.FD.STN.DL, FEC.FT.ACC.SH, FEC.FT.GPE.RM, FEC.FT.GPI.RM, FEC.FT.VP.VM |
| FECEXE | Executive/Cognitive Loop | FEC.FD.STN.CD, FEC.FT.CN.HD, FEC.FT.GPE.DS, FEC.FT.GPI.DS, FEC.FT.SNC.LT, FEC.FT.SNR.RM |
| FECLM | Motor Motivational Salience | FEC.FT.ACC.CORE, FEC.FT.CN.TL, FEC.FT.IPAC.LT, FEC.FT.PU.VT, FEC.FT.SNC.MED, FEC.FT.SNR.MED, FEC.FT.VP.DL |
| FECME | Motor Extensor Loop | FEC.FD.STN.MED, FEC.FD.TH.PF, FEC.FT.GPE.MED, FEC.FT.GPI.MED, FEC.FT.PU.MED, FEC.FT.SNR.DL |
| FECMF | Motor Flexor Loop | FEC.FD.STN.LT, FEC.FD.TH.CM, FEC.FT.GPE.LT, FEC.FT.GPI.LT, FEC.FT.PU.LT, FEC.HT.TG.IPD, FEC.HT.TG.RMTG |
| FECOM | Oculomotor and Auditory/Association Loop | FEC.FD.STN.ICD, FEC.FT.CN.BD, FEC.FT.GPE.DL, FEC.FT.GPI.DL, FEC.FT.SNR.VL |
Cognitive Motivational Salience
| Component ID | Component Name | Type | Service | Function | Comments |
| FEC.FD.STN.DL | Subthalamic Nucleus Dorsolateral | nucleus | FEU | Motivational loop | |
| FEC.FT.ACC.SH | Nucleus Accumbens Shell | nucleus | FEU | cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects |
|
| FEC.FT.GPE.RM | Globus Pallidus External Rostromedial | nucleus | FEU | Motivational loop | |
| FEC.FT.GPI.RM | Globus Pallidus Internal Rostromedial | nucleus | FEU | Motivational loop | |
| FEC.FT.VP.VM | Ventral Pallidum Ventromedial | nucleus | FEU | motivational loop, NAcc-shell |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FEC.FD.STN.DL | FEC.FT.GPE.RM | nucleus-nucleus | Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (STN -> GPe, abstract) |
| FEC.FT.GPI.RM | nucleus-nucleus | Basal Ganglia Activity (STN -> GPi, abstract) | |
| FEC.FT.VP.VM | nucleus-nucleus | Functional subdivisions of the subthalamic nucleus (STN -> VP, abstract) | |
| FEC.FT.ACC.SH | FEC.FT.VP.VM | nucleus-nucleus-gaba | Craving (NACC -> VPAL, abstract) |
| FEC.FT.GPE.RM | FEC.FT.GPI.RM | nucleus-nucleus-gaba | (unknown reference) |
External Inbound Region Connections:
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Cortical | |||||
| NCP | FEC.FT.VP.VM | NCP.FD.TH.MDC | Central Mediodorsal Nucleus of Thalamus | nucleus-nucleus-gaba | Saccadic Vision (BG -> Thalamus, abstract) |
| NDM | FEC.FT.GPI.RM | NDM.FD.TH.MDM | Medial Mediodorsal Nucleus of Thalamus | nucleus-nucleus-gaba | Saccadic Vision (BG -> Thalamus, abstract) |
| Subcortical | |||||
| FAM | FEC.FT.ACC.SH | FAM.FD.MHB | Medial Habenula | nucleus-nucleus-gaba | Connectivity map of the habenula (NAc -> M, abstract) |
| FEC.FT.VP.VM | FAM.FD.LHB.MED | Lateral Habenula Medial Part | nucleus-nucleus-gaba | Both LHb and MHb control the dopaminergic and serotonergic systems (VP -> LHbM, abstract) | |
| FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | nucleus-nucleus-gaba | Saccadic Vision (BG -> Thalamus, abstract) | ||
| FEC | FEC.FD.STN.DL | FEC.FT.PU.VT | Ventral Putamen | nucleus-nucleus | (unknown reference) |
| FEC.FT.SNR.MED | Substantia Nigra Pars Reticulata Medial | nucleus-nucleus | (unknown reference) | ||
| FEC.FT.ACC.SH | FEC.FT.IPAC.LT | Lateral Interstitial Anterior Commissural Nucleus | nucleus-nucleus-gaba | (unknown reference) | |
| FEC.FT.GPE.RM | FEC.FT.SNR.MED | Substantia Nigra Pars Reticulata Medial | nucleus-nucleus-gaba | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
| FEC.FT.GPI.RM | FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | nucleus-nucleus-gaba | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
| FEC.FT.VP.VM | FEC.HT.TG.RMTG | Rostromedial Tegmental Nucleus | nucleus-nucleus-gaba | (unknown reference) | |
| LAC | FEC.FT.ACC.SH | LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | nucleus-nucleus-gaba | (unknown reference) |
| LMC | FEC.FT.ACC.SH | LMC.FT.NBM | Basal Nucleus of Meynert | nucleus-nucleus-gaba | Affective basal ganglia circuit (NACC -> nBM, abstract) |
| FEC.FT.VP.VM | LMC.HT.TG.PPN | Pedunculopontine Tegmental Nuclei | nucleus-nucleus-gaba | Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VPAL -> PPTG, abstract) | |
| LMC.MM.VTA | Ventral Tegmental Area | nucleus-nucleus-gaba | Craving (VPAL -> VTA, abstract) |
Executive/Cognitive Loop
| Component ID | Component Name | Type | Service | Function | Comments |
| FEC.FD.STN.CD | Subthalamic Nucleus Caudal | nucleus | FEU | Executive loop | |
| FEC.FT.CN.HD | Caudate Nucleus Head | nucleus | FEU | Feedback processing, result of incorrect categorization | |
| FEC.FT.GPE.DS | Globus Pallidus External Dorsal | nucleus | FEU | Executive loop | |
| FEC.FT.GPI.DS | Globus Pallidus Internal Dorsal | nucleus | FEU | Executive loop | |
| FEC.FT.SNC.LT | Substantia Nigra Pars Compacta Lateral | nucleus | FEU | executive loop | |
| FEC.FT.SNR.RM | Substantia Nigra Pars Reticulata Rostromedial | nucleus | FEU | Executive loop |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FEC.FD.STN.CD | FEC.FT.GPE.DS | nucleus-nucleus | Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (STN -> GPe, abstract) |
| FEC.FT.GPI.DS | nucleus-nucleus | Basal Ganglia Activity (STN -> GPi, abstract) | |
| FEC.FT.SNR.RM | nucleus-nucleus | (unknown reference) | |
| FEC.FT.CN.HD | FEC.FT.GPI.DS | nucleus-nucleus-gaba | Habenula Connections (CPu -> GPi, abstract) |
| FEC.FT.SNC.LT | nucleus-nucleus-gaba | Saccades and smooth movements (CN -> SN, abstract) | |
| FEC.FT.SNR.RM | nucleus-nucleus-gaba | Saccades and smooth movements (CN -> SN, abstract) | |
| FEC.FT.GPE.DS | FEC.FT.GPI.DS | nucleus-nucleus-gaba | (unknown reference) |
| FEC.FT.SNR.RM | nucleus-nucleus-gaba | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
| FEC.FT.GPI.DS | FEC.FT.SNC.LT | nucleus-nucleus-gaba | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) |
| FEC.FT.SNR.RM | FEC.FT.SNC.LT | nucleus-nucleus-gaba | (unknown reference) |
External Inbound Region Connections:
External Outbound Region Connections:
Motor Motivational Salience
| Component ID | Component Name | Type | Service | Function | Comments |
| FEC.FT.ACC.CORE | Nucleus Accumbens Core | nucleus | FEU | cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future |
|
| FEC.FT.CN.TL | Caudate Nucleus Tail | nucleus | FEU | Successful classification learning, correct categorization | |
| FEC.FT.IPAC.LT | Lateral Interstitial Anterior Commissural Nucleus | nucleus | FAU | Striatal territory | |
| FEC.FT.PU.VT | Ventral Putamen | nucleus | FEU | Evaluation of flavors, taste, motivation loop | |
| FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | nucleus | FEU | motivational loop | |
| FEC.FT.SNR.MED | Substantia Nigra Pars Reticulata Medial | nucleus | FEU | Motivational loop | |
| FEC.FT.VP.DL | Ventral Pallidum Dorsolateral | nucleus | FEU | motivational loop, NAcc-core |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FEC.FT.ACC.CORE | FEC.FT.SNC.MED | nucleus-nucleus-gaba | (unknown reference) |
| FEC.FT.SNR.MED | nucleus-nucleus-gaba | Craving (NACC -> SNr, abstract) | |
| FEC.FT.VP.DL | nucleus-nucleus-gaba | Craving (NACC -> VPAL, abstract) | |
| FEC.FT.CN.TL | FEC.FT.SNR.MED | nucleus-nucleus-gaba | Saccades and smooth movements (CN -> SN, abstract) |
| FEC.FT.PU.VT | FEC.FT.SNR.MED | nucleus-nucleus-gaba | (unknown reference) |
| FEC.FT.SNR.MED | FEC.FT.SNC.MED | nucleus-nucleus-gaba | (unknown reference) |
| FEC.FT.VP.DL | FEC.FT.SNR.MED | nucleus-nucleus-gaba | Craving (VPAL -> SNr, abstract) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Reference |
| Cortical | |||||
| NDM | FEC.FT.ACC.CORE | NDM.FD.TH.PV | Paraventricular Nucleus of Thalamus | nucleus-nucleus | (unknown reference) |
| NDM.NC.AL.FPC | Lateral Frontopolar Cortex | neocortex-nucleus | Affective basal ganglia circuit (OMPFC -> NACC, abstract) | ||
| FEC.FT.CN.TL | NDM.NC.AL.ROFCR | Most Rostral Orbitofrontal Cortex | neocortex-nucleus | Global visual system (FrontalCortex -> BGA, abstract) | |
| FEC.FT.PU.VT | NDM.NC.AL.VACG | Ventral Anterior Cingulate Area | neocortex-nucleus | Global visual system (FrontalCortex -> BGA, abstract) | |
| FEC.FT.SNR.MED | NDM.NC.AL.FPC | Lateral Frontopolar Cortex | neocortex-nucleus | Global visual system (FrontalCortex -> BGA, abstract) | |
| Subcortical | |||||
| FAM | FEC.FT.ACC.CORE | FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | nucleus-nucleus | (unknown reference) |
| FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | nucleus-nucleus | Amygdala and its network (BLN -> NACC, abstract) | ||
| FEC.FT.CN.TL | FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) | |
| FEC.FT.SNC.MED | FAM.FT.BNST | Bed Nucleus of Stria Terminalis | nucleus-nucleus | (unknown reference) | |
| FEC | FEC.FT.IPAC.LT | FEC.FT.ACC.SH | Nucleus Accumbens Shell | nucleus-nucleus-gaba | (unknown reference) |
| FEC.FT.PU.VT | FEC.FD.STN.DL | Subthalamic Nucleus Dorsolateral | nucleus-nucleus | (unknown reference) | |
| FEC.FT.SNC.MED | FEC.FT.GPI.RM | Globus Pallidus Internal Rostromedial | nucleus-nucleus-gaba | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
| FEC.HT.TG.RMTG | Rostromedial Tegmental Nucleus | nucleus-nucleus-gaba | Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> SNc, abstract) | ||
| FEC.FT.SNR.MED | FEC.FD.STN.DL | Subthalamic Nucleus Dorsolateral | nucleus-nucleus | (unknown reference) | |
| FEC.FT.GPE.RM | Globus Pallidus External Rostromedial | nucleus-nucleus-gaba | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | ||
| FMM | FEC.FT.ACC.CORE | FMM.FD.TH.RH | Rhomboidal Nucleus of Thalamus | nucleus-nucleus | (unknown reference) |
| FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | allocortex-nucleus | Nucleus Accumbens (CA1 -> NACC, abstract) | ||
| FMM.FT.HF.SUBD | Distal Subiculum | allocortex-nucleus | Nucleus Accumbens (SUB -> NACC, abstract) | ||
| FMM.FT.HF.SUBP | Proximal Subiculum | allocortex-nucleus | Nucleus Accumbens (SUB -> NACC, abstract) | ||
| FMM.NC.PH.LEC | Lateral Entorhinal Cortex | neocortex-nucleus | Nucleus Accumbens (EC -> NACC, abstract) | ||
| FMM.NC.PH.PAS | Parasubiculum | neocortex-nucleus | Nucleus Accumbens (PAS -> NACC, abstract) | ||
| FMM.NC.PH.PER | Perirhinal Cortex | neocortex-nucleus | Nucleus Accumbens (PRR -> NACC, abstract) | ||
| LMC | FEC.FT.SNC.MED | LMC.HT.LC | Locus Coeruleus | nucleus-nucleus-NE | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Cortical | |||||
| NMA | FEC.FT.SNR.MED | NMA.FD.TH.MDL | Lateral Mediodorsal Nucleus of Thalamus | nucleus-nucleus-gaba | Saccadic Vision (BG -> Thalamus, abstract) |
| FEC.FT.VP.DL | NMA.FD.TH.MDL | Lateral Mediodorsal Nucleus of Thalamus | nucleus-nucleus-gaba | Saccadic Vision (BG -> Thalamus, abstract) | |
| Subcortical | |||||
| FAM | FEC.FT.ACC.CORE | FAM.FD.LHB.LT | Lateral Habenula Lateral Part | nucleus-nucleus-gaba | Connectivity map of the habenula (NAc -> L, abstract) |
| FEC.FT.PU.VT | FAM.FT.EPF | Endopiriform Nucleus | nucleus-nucleus-gaba | Connectivity map of the habenula (CPu -> EP, abstract) | |
| FEC.FT.SNC.MED | FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | nucleus-nucleus-DA | (unknown reference) | |
| FEC | FEC.FT.CN.TL | FEC.FT.GPI.RM | Globus Pallidus Internal Rostromedial | nucleus-nucleus-gaba | Habenula Connections (CPu -> GPi, abstract) |
| FEC.FT.IPAC.LT | FEC.FT.SNR.DL | Substantia Nigra Pars Reticulata Dorsolateral | nucleus-nucleus-gaba | (unknown reference) | |
| FEC.FT.VP.VM | Ventral Pallidum Ventromedial | nucleus-nucleus-gaba | (unknown reference) | ||
| FEC.FT.SNC.MED | FEC.FT.ACC.SH | Nucleus Accumbens Shell | nucleus-nucleus-DA | Connectivity map of the habenula (SNc -> CPu, abstract) | |
| FEC.FT.SNR.MED | FEC.HT.TG.IPD | Interpeduncular Nucleus | nucleus-nucleus-gaba | (unknown reference) | |
| LAC | FEC.FT.SNC.MED | LAC.FD.HT.SUM | Supramammillary Nucleus | nucleus-nucleus-DA | (unknown reference) |
| LMC | FEC.FT.ACC.CORE | LMC.MM.VTA | Ventral Tegmental Area | nucleus-nucleus-gaba | Reward circuit of human brain (NACC -> VTA, abstract) |
| LRC | FEC.FT.SNC.MED | LRC.HT.PRF.PVR | Parvocellular Reticular Nucleus | nucleus-nucleus-DA | (unknown reference) |
Motor Extensor Loop
| Component ID | Component Name | Type | Service | Function | Comments |
| FEC.FD.STN.MED | Subthalamic Nucleus Medial | nucleus | FEU | Motor Extensor loop | |
| FEC.FD.TH.PF | Parafascicular Nucleus of Thalamus | nucleus | FEU | Stimulation of acetylcholine release in dorsal striata | |
| FEC.FT.GPE.MED | Globus Pallidus External Medial | nucleus | FEU | Extensor loop | |
| FEC.FT.GPI.MED | Globus Pallidus Internal Medial | nucleus | FEU | Motor extensor loop | |
| FEC.FT.PU.MED | Dorsal Putamen Medial | nucleus | FEU | Extensor motor initiation | |
| FEC.FT.SNR.DL | Substantia Nigra Pars Reticulata Dorsolateral | nucleus | FEU | Extensor motor loop, head |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FEC.FD.STN.MED | FEC.FT.GPE.MED | nucleus-nucleus | Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (STN -> GPe, abstract) |
| FEC.FT.GPI.MED | nucleus-nucleus | Basal Ganglia Activity (STN -> GPi, abstract) | |
| FEC.FT.SNR.DL | nucleus-nucleus | Saccadic Vision (STN -> SNpr, abstract) | |
| FEC.FD.TH.PF | FEC.FT.PU.MED | nucleus-nucleus | (unknown reference) |
| FEC.FT.GPE.MED | FEC.FT.GPI.MED | nucleus-nucleus-gaba | (unknown reference) |
| FEC.FT.SNR.DL | nucleus-nucleus-gaba | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
| FEC.FT.GPI.MED | FEC.FD.TH.PF | nucleus-nucleus-gaba | Saccadic Vision (BG -> Thalamus, abstract) |
| FEC.FT.PU.MED | FEC.FT.GPE.MED | nucleus-nucleus-gaba | Basal Ganglia Activity (PU -> GPo, abstract) |
| FEC.FT.GPI.MED | nucleus-nucleus-gaba | Habenula Connections (CPu -> GPi, abstract) | |
| FEC.FT.SNR.DL | nucleus-nucleus-gaba | Global visual system (Striatum -> SNr, abstract) |
External Inbound Region Connections:
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Cortical | |||||
| NMA | FEC.FT.GPI.MED | NMA.FD.TH.VA | Ventral Anterior Nucleus | nucleus-nucleus-gaba | Thalamocortical relationships (sVA -> VA, abstract) |
| FEC.FT.SNR.DL | NMA.FD.TH.VA | Ventral Anterior Nucleus | nucleus-nucleus-gaba | Thalamocortical relationships (sVA -> VA, abstract) | |
| Subcortical | |||||
| FEC | FEC.FT.SNR.DL | FEC.FT.SNC.LT | Substantia Nigra Pars Compacta Lateral | nucleus-nucleus-gaba | Oculomotor decision-making (SNr -> SNc) |
| LRC | FEC.FT.SNR.DL | LRC.MM.SC.INT | Intermediate Superior Colliculus | nucleus-nucleus-gaba | Global visual system (SNr -> SCi, abstract) |
Motor Flexor Loop
| Component ID | Component Name | Type | Service | Function | Comments |
| FEC.FD.STN.LT | Subthalamic Nucleus Lateral | nucleus | FEU | Motor Flexor loop | |
| FEC.FD.TH.CM | Centromedian Nucleus of Thalamus | nucleus | FEU | Control of level of cortical activity | |
| FEC.FT.GPE.LT | Globus Pallidus External Lateral | nucleus | FEU | Flexor loop | |
| FEC.FT.GPI.LT | Globus Pallidus Internal Lateral | nucleus | FEU | Motor flexor loop | |
| FEC.FT.PU.LT | Dorsal Putamen Lateral | nucleus | FEU | Flexor motor initiation | |
| FEC.HT.TG.IPD | Interpeduncular Nucleus | nucleus | FEU | postural control, voluntary arm and eye movements | |
| FEC.HT.TG.RMTG | Rostromedial Tegmental Nucleus | nucleus | FEU | locomotion - walking, running |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FEC.FD.STN.LT | FEC.FT.GPE.LT | nucleus-nucleus | Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (STN -> GPe, abstract) |
| FEC.FT.GPI.LT | nucleus-nucleus | Basal Ganglia Activity (STN -> GPi, abstract) | |
| FEC.HT.TG.RMTG | nucleus-nucleus | (unknown reference) | |
| FEC.FD.TH.CM | FEC.FT.PU.LT | nucleus-nucleus | Thalamocortical relationships (CM -> pCM, abstract) |
| FEC.FT.GPE.LT | FEC.FT.GPI.LT | nucleus-nucleus-gaba | (unknown reference) |
| FEC.FT.GPI.LT | FEC.FD.TH.CM | nucleus-nucleus-gaba | Thalamocortical relationships (sCM -> CM, abstract) |
| FEC.FT.PU.LT | FEC.FT.GPI.LT | nucleus-nucleus-gaba | Habenula Connections (CPu -> GPi, abstract) |
| FEC.HT.TG.IPD | FEC.FD.STN.LT | nucleus-nucleus-ACh | (unknown reference) |
| FEC.HT.TG.RMTG | FEC.HT.TG.IPD | nucleus-nucleus-gaba | (unknown reference) |
External Inbound Region Connections:
External Outbound Region Connections:
Oculomotor and Auditory/Association Loop
| Component ID | Component Name | Type | Service | Function | Comments |
| FEC.FD.STN.ICD | Subthalamic Nucleus Internal Caudal | nucleus | FEU | Oculomotor loop | |
| FEC.FT.CN.BD | Caudate Nucleus Body | nucleus | FEU | Oculomotor learning | |
| FEC.FT.GPE.DL | Globus Pallidus External Dorsolateral | nucleus | FEU | Oculomotor loop | |
| FEC.FT.GPI.DL | Globus Pallidus Internal Dorsolateral | nucleus | FEU | Oculomotor loop | |
| FEC.FT.SNR.VL | Substantia Nigra Pars Reticulata Ventrolateral | nucleus | FEU | Oculomotor loop |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FEC.FD.STN.ICD | FEC.FT.GPE.DL | nucleus-nucleus | Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (STN -> GPe, abstract) |
| FEC.FT.GPI.DL | nucleus-nucleus | Basal Ganglia Activity (STN -> GPi, abstract) | |
| FEC.FT.SNR.VL | nucleus-nucleus | (unknown reference) | |
| FEC.FT.CN.BD | FEC.FT.GPI.DL | nucleus-nucleus-gaba | Habenula Connections (CPu -> GPi, abstract) |
| FEC.FT.SNR.VL | nucleus-nucleus-gaba | Saccades and smooth movements (CN -> SN, abstract) | |
| FEC.FT.GPE.DL | FEC.FT.GPI.DL | nucleus-nucleus-gaba | (unknown reference) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Reference |
| Cortical | |||||
| NCP | FEC.FT.CN.BD | NCP.FD.TH.LI | Limitans Nucleus of Thalamus | nucleus-nucleus | (unknown reference) |
| NDM | FEC.FT.CN.BD | NDM.NC.AL.VACG | Ventral Anterior Cingulate Area | neocortex-nucleus | Global visual system (FrontalCortex -> BGA, abstract) |
| NPE | FEC.FT.CN.BD | NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | neocortex-nucleus | Global visual system (FrontalCortex -> BGA, abstract) |
| NSA | FEC.FT.CN.BD | NSA.NC.IT.TE | Inferotemporal Cortex | neocortex-nucleus | (unknown reference) |
| NSA.NC.TTG.A2 | Auditory Association Area | neocortex-nucleus | (unknown reference) | ||
| Subcortical | |||||
| LMC | FEC.FD.STN.ICD | LMC.MM.RP.SUC | Superior Central Raphe Nucleus | nucleus-nucleus-5HT | (unknown reference) |
| LRC | FEC.FD.STN.ICD | LRC.MM.PT.PTA | Anterior Pretectum Nucleus | nucleus-nucleus | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Cortical | |||||
| NPE | FEC.FT.GPI.DL | NPE.FD.TH.LP | Lateral Posterior Nucleus of Thalamus | nucleus-nucleus-gaba | Saccadic Vision (BG -> Thalamus, abstract) |
| Subcortical | |||||
| FEC | FEC.FD.STN.ICD | FEC.HT.TG.IPD | Interpeduncular Nucleus | nucleus-nucleus | (unknown reference) |
| FEC.FT.CN.BD | FEC.FT.PU.LT | Dorsal Putamen Lateral | nucleus-nucleus-gaba | Regulation of Social Brain (Caud -> Put, abstract) | |
| FEC.FT.SNR.DL | Substantia Nigra Pars Reticulata Dorsolateral | nucleus-nucleus-gaba | Global visual system (Striatum -> SNr, abstract) | ||
| LRC | FEC.FT.SNR.VL | LRC.MM.SC.INT | Intermediate Superior Colliculus | nucleus-nucleus-gaba | Saccadic Vision (BG -> SCi, abstract) |
Thirdparty Circuits
(generated)
- Physiology and pathophysiology of lower urinary tract - see Reference (CM.ONUF)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) DVM=Vagus Nucleus,LAC.HL.VGN IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG IML=Intermediolateral Nucleus,LAC.SC.IZ.IML LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO NBM=Basal Nucleus of Meynert,LMC.FT.NBM ONF=Onuf's Nucleus,LPC.SC.VH.ONF PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG PU=Dorsal Putamen Lateral,FEC.FT.PU.LT PVN=Paraventricular Nucleus,LAC.FD.HT.PV SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS VTA=Ventral Tegmental Area,LMC.MM.VTA ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI
- Both LHb and MHb control the dopaminergic and serotonergic systems - see Reference (CF.HB-DA5HT)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO LS=Lateral Septal Nucleus,FAM.FT.SEP.LT MHb=Medial Habenula,FAM.FD.MHB MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) MS=Medial Septal Nucleus,FAM.FT.SEP.MED PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei) RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Habenula Connections - see Reference (CF.HB-CONNECTIONS)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) IP=Interpeduncular Nucleus,FEC.HT.TG.IPD LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO MHb=Medial Habenula,FAM.FD.MHB MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC PB=Endocrine Glands,TARGET.TEA.ENDOCRINE S=Septal Nuclei,FAM.FT.SEP SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT VTA=Ventral Tegmental Area,LMC.MM.VTA
- Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)
AMYG=Amygdala,FAM.FT.AM CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL Thalamus=Thalamus,FD.TH VTA=Ventral Tegmental Area,LMC.MM.VTA
- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Normal Functional Anatomy of Basal Ganglia - see Reference (CM.NORMAL-BG-ANATOMY)
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) VA=Ventral Anterior Nucleus,NMA.FD.TH.VA VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
- Regulation of the rapid eye movement (REM) sleep by habenular projection - see Reference (CF.REM-HB)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DTG=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG EPN=Endopiriform Nucleus,FAM.FT.EPF GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) LHT=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED NI=Incertus Nucleus,FAM.HT.TG.NI RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA VTG=Ventral Tegmental Area,LMC.MM.VTG
- Amygdala and its network - see Reference (CF.AM-NET)
BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP CEA=Central Amygdala,FAM.FT.AM.CEA (see Amygdala) EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ITC=Inferotemporal Cortex,NSA.NC.IT.TE LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala) LHB=Lateral Habenula,FAM.FD.LHB (see Habenula) MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG STC=Wernicke's area A3,NSA.NC.STG.A3 VGDM=Vagus Nucleus,LAC.HL.VGN VTA=Ventral Tegmental Area,LMC.MM.VTA
- Head Direction Cell Circuit - see Reference (CT.HEAD-DIRECTION)
AD=Anterodorsal Nucleus,FMM.FD.TH.AD DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LHAB=Habenula,FAM.FD.HB LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN NPRP=Prepositus Nucleus,LRC.HL.NPH PC=Parietal Lobe,NC.LOBE.PAR PRHC=Postrhinal Cortex,FMM.NC.PH.POR PSUB=Postsubiculum,FMM.NC.PH.POS RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG VC=Occipital Lobe,NC.LOBE.OCC
- Contribution of nAChR subunits to nicotine withdrawal symptoms - see Reference (CF.HB-NICOTINE)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LC=Locus Coeruleus,LMC.HT.LC LHB=Lateral Habenula,FAM.FD.LHB (see Habenula) MHB=Medial Habenula,FAM.FD.MHB
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
- Connectivity of dorsal diencephalic conduction system - see Reference (CF.HB-ASYMM)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) MHb=Medial Habenula,FAM.FD.MHB
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Saccadic Vision - see Reference (CP.SACCADIC-VISION)
BG=Basal Ganglia,FEC.FT.BG CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FrontalCortex=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) Thalamus=Thalamus,FD.TH VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Contributions of Diencephalon to Recognition Memory - see Reference (CT.RECOGNITION-MEMORY)
AD=Anterodorsal Nucleus,FMM.FD.TH.AD AM=Anteromedial Nucleus,NCP.FD.TH.AM AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) AV=Anteroventral Nucleus,FMM.FD.TH.AV CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB MDmc=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MID=Midline Nuclear Group of Thalamus,FD.TH.MTH (see Cognitive Thalamus) MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) Parasub=Parasubiculum,FMM.NC.PH.PAS Perirhinal=Perirhinal Cortex,FMM.NC.PH.PER PostCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Presub=Presubiculum,FMM.NC.PH.PRS Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) SubPrePara=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) mPULV=Medial Pulvinar,NPE.FD.TH.MPV
- Thalamocortical relationships - see Reference (CL.THALAMUS-PROJECTIONS)
A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MGN=Medial Geniculate Body,NSA.FD.TH.MGB P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus) VA=Ventral Anterior Nucleus,NMA.FD.TH.VA VL=Ventral Lateral Nucleus,NMA.FD.TH.VL VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia) pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) pLGN=Primary Visual Cortex,NSA.NC.OCC.V1 pLP=Superior Parietal Lobule,NC.SPL pMD=Prefrontal Cortex,NC.AL.PFC pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1 pP=Insular Cortex,NC.INS pVA=Supplementary Motor Cortex,NMA.NC.SMC pVL=Motor Cortex,NMA.NC.MC pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1 pVPM=Precentral Cortex,NCP.NC.PO.PCC s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) s1MD=Septal Nuclei,FAM.FT.SEP s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV s1VL=Dentate Nucleus,LLC.HT.CR.DN s2A=Mammillary Body,FD.MB (see Hypothalamus) s2MD=Piriform Cortex,NSA.NC.PH.PIR s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR s2VL=Basal Ganglia,FEC.FT.BG s3MD=Prefrontal Cortex,NC.AL.PFC sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) sLD=Superior Parietal Lobule,NC.SPL sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) sVA=Basal Ganglia,FEC.FT.BG sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn) sVPM=Solitary Nucleus,LPC.HL.SOL
References
(generated)
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